Clinical trials
Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer) clinical trials
Below are recruiting chronic wound of the lower limb (leg ulcer or foot ulcer) clinical trials, each written for real people, not researchers. We’re tracking 173 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07747896Recruiting
Coordinated primary care team for hard-to-heal wounds
This trial tests whether a team of different healthcare professionals working together in your primary care clinic can help heal stubborn wounds (ulcers) that have not healed with standard care. If you join, you may get more coordinated care and support to help your wound heal.
HillerødAges 18 years+ - NCT06916663Recruiting
Upper body vs. combined exercise during diabetic foot ulcer treatment
This trial compares two exercise programs for people with diabetic foot ulcers: one that uses only upper body exercises and one that combines upper body with non-weight bearing lower body exercises. The goal is to see which approach helps healing while keeping weight off the foot.
CairoAges 18–65 - NCT05930210RecruitingPhase 3
Study gel treatment for diabetic foot ulcers that won’t heal
This Phase 3 trial tests ENERGI-F703 gel to help heal diabetic foot ulcers that have not improved for at least 4 weeks. It may help some people whose wounds meet specific size and non-infection criteria.
Miami, FloridaAges 18 years+ - NCT06832787Recruiting
Negative pressure therapy for diabetic foot wounds
This study tests whether combining negative pressure wound therapy (a special dressing that uses gentle suction) can help diabetic foot wounds heal better after toe amputation. It is looking for people who have had their big or little toe removed and have adequate blood flow to the foot.
SingaporeAges 21–100 - NCT07406152Recruiting
A gel for hard-to-heal chronic wounds
This study tests a new gel and applicator for chronic wounds that are hard to heal, like bed sores, diabetic foot ulcers, and leg ulcers. The goal is to see if the gel helps wounds heal safely.
Vitoria-Gasteiz, ÁlavaAges 18 years+ - NCT07209475RecruitingPhase 4
Amnio-Maxx for healing diabetic foot ulcers
This trial tests whether a special wound dressing called Amnio-Maxx can help heal foot ulcers in people with diabetes. You may qualify if you have a diabetic foot ulcer that hasn't healed much with standard care.
Burbank, CaliforniaAges 18 years+ - NCT04791449Recruiting
Exercise program for healing diabetic foot ulcers
This study tests whether an exercise program can help wounds (ulcers) heal faster in people with diabetic foot ulcers. It mainly looks for adults with type 2 diabetes and enough blood flow to the foot, and checks safety and healing progress.
Albuquerque, New MexicoAges 20–80 - NCT07607106Recruiting
New Wound-Healing Gel for Chronic Leg and Foot Ulcers
This trial tests a new gel (called BU002) designed to clean and help heal chronic open sores on the legs or feet. The gel may work better than current treatments for wounds that have been open for months and aren't healing on their own.
Santiago, Metropolitana de SantiagoAges 60 years+ - NCT06439667Enrolling by invitation
Home Exercise Program for Diabetic Foot Ulcers
This trial tests a home exercise program delivered by video to help heal diabetic foot ulcers. It's designed for people who can walk on their own and have a relatively new ulcer.
Los Angeles, CaliforniaAges 18 years+ - NCT02652169Recruiting
Antibiotic or antiseptic treatment for chronic leg ulcers
This study tests a wound treatment using topical antibiotics or antiseptics to help chronic (long-lasting) leg ulcers heal and control local infection. It may help people whose ulcers are not responding well to standard care.
ViennaAges 18 years+ - NCT05491577Recruiting
Diabetes foot nerve disease patients without ulcers
This study looks at what affects changes in quality of life in people with diabetes who have a long-term, wound-free Charcot foot. It may help doctors understand what matters most for day-to-day wellbeing in this condition.
Boulogne-sur-Mer, Pas-de-CalaisAges 18 years+ - NCT07326553RecruitingPhase 4
Placental membrane for diabetic foot ulcers
This trial tests whether a special placental membrane dressing helps diabetic foot ulcers heal faster. You may qualify if you have a diabetes-related foot ulcer that hasn't been healing well with standard care.
Phoenix, ArizonaAges 45–85 - NCT07216599Recruiting
Imaging foot wounds with light and sound
This trial uses a special camera that combines light and sound to take pictures of chronic foot wounds caused by poor blood flow. It may help doctors see how well the wound is healing without needing extra tests.
Buffalo, New YorkAges 18 years+ - NCT06616844Recruiting
Patch for non-healing diabetic foot ulcers
This trial tests a special patch made from pig tissue (placenta) placed on diabetic foot ulcers that are not healing well. If you have a foot ulcer that has been present for 4 to 52 weeks and is not shrinking, you may be able to join the study.
Fresno, CaliforniaAges 18 years+ - NCT06154915Recruiting
Immune cells in diabetic foot ulcers
This study looks at immune cells in chronic foot ulcers caused by diabetes. It may help researchers understand how these ulcers heal, which could lead to better treatments.
Huddinge, Stockholm CountyAges 18–98 - NCT07159282RecruitingPhase 4
Placental graft for diabetic foot ulcers that didn't close
This trial tests a placental-based graft for diabetic foot ulcers that did not heal after 12 weeks of standard care in a previous study (CAMPX). It aims to help people whose wounds are still open despite good wound care.
Hollywood, FloridaAges 18 years+ - NCT07877948Recruiting
Combination therapy for diabetic nerve pain and foot ulcers
This study tests whether a treatment called Bionerv E+ helps with nerve pain and healing of foot ulcers in people with type 2 diabetes, compared with a standard vitamin B complex. If you have diabetes-related nerve damage and a foot ulcer that is not too severe, this study might help you understand if this new option works.
Cheras, Kuala LumpurAges 18 years+ - NCT07209358Recruiting
Study of a new treatment for diabetic foot ulcers
This trial tests a new product (EDX110) to help heal diabetic foot ulcers that haven't improved with standard care. It's for people with diabetes who have a non-infected or mildly infected ulcer on their foot.
Phoenix, ArizonaAges 18–90 - NCT07116174Recruiting
Testing a new amniotic membrane dressing for diabetic foot ulcers
This study tests a new wound dressing made from amniotic membrane, called Xcell Amnio Matrix, to see if it helps heal diabetic foot ulcers that have not healed with standard treatments. If you qualify, you would receive the dressing along with regular wound care.
Fresno, CaliforniaAges 18 years+ - NCT06550596Recruiting
Amnion membrane for diabetic foot ulcers
This trial tests a wound covering made from donated amniotic tissue (dehydrated human amnion membrane) placed on a diabetic foot ulcer that isn't healing. It aims to see if adding this membrane to standard wound care helps the ulcer close faster.
Thousand Oaks, CaliforniaAges 18 years+ - NCT06564831Recruiting
Placental graft for diabetic foot ulcers
This study tests whether a special placental tissue graft placed on a diabetic foot ulcer helps it heal faster than standard wound care alone. It is for people with a diabetic foot ulcer that has not healed after 4 weeks of usual care.
Clinton Township, MichiganAges 18 years+ - NCT06449638Recruiting
Testing new wound treatments for hard-to-heal diabetic foot ulcers
This trial compares several advanced wound treatments (called CAMPs) plus standard care versus standard care alone for diabetic foot ulcers that are slow to heal. The goal is to see if adding these treatments helps ulcers close faster.
Omaha, NebraskaAges 18 years+ - NCT03942081Recruiting
Imaging test for diabetic foot wounds
This study looks at how images of a current foot wound in people with diabetes can be used to help doctors. It may help improve how foot ulcers are evaluated while you receive usual care.
Iowa City, IowaAges 21–100 - NCT06153589Recruiting
Music therapy for leg ulcer pain relief
This trial tests whether listening to music during wound cleaning can reduce pain for people with leg ulcers caused by vein or artery problems. It aims to make the procedure more comfortable.
Fort-de-FranceAges 18 years+
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Common questions
- Are there clinical trials for chronic wound of the lower limb (leg ulcer or foot ulcer)?
- Yes. Clin2 currently lists 173 recruiting chronic wound of the lower limb (leg ulcer or foot ulcer) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic wound of the lower limb (leg ulcer or foot ulcer) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic wound of the lower limb (leg ulcer or foot ulcer) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.