Clinical trials
Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer) clinical trials
Below are recruiting chronic wound of the lower limb (leg ulcer or foot ulcer) clinical trials, each written for real people, not researchers. We’re tracking 180 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07089602RecruitingPhase 4
Placental membrane for diabetic and venous leg ulcers
This trial tests if a placental membrane product, when added to standard wound care, helps heal diabetic foot ulcers and venous leg ulcers faster than standard care alone.
Philidelphia, PennsylvaniaAges 18 years+ - NCT06826339RecruitingPhase 4
Advanced wound treatments for diabetic foot and leg ulcers
This study compares several advanced wound treatments (called CAMPs) plus standard care to standard care alone for hard-to-heal diabetic foot ulcers and venous leg ulcers. It aims to see if the extra treatments help wounds close faster and prevent complications.
Monroeville, PennsylvaniaAges 21 years+ - NCT06453187Enrolling by invitation
Testing wound dressings for diabetic and vein ulcers
This study tests whether special wound dressings (called CAMPs) can help heal diabetic foot ulcers and venous leg ulcers faster. If you have a hard-to-heal sore on your foot or leg, this trial may be an option.
Los Angeles, CaliforniaAges 18–80 - NCT05172089Recruiting
Treating recurring infection in diabetic foot ulcers
This trial studies an approach to treat bacteria living in a diabetic foot ulcer and help prevent the ulcer from coming back. You may be able to join if you have an open diabetic foot ulcer and good blood flow to the wound.
Tucson, ArizonaAges 18 years+ - NCT05610865RecruitingPhase 1
Stem cell treatment for chronic diabetic foot ulcers
This Phase 1 study tests whether stem cells taken from fat tissue (after a small procedure) can help heal a long-lasting diabetic foot ulcer. It mainly aims to help ulcers that are limited to soft tissue and have good blood flow to the foot.
Lahore, Punjab ProvinceAges 20–60 - NCT03594344Recruiting
Extra hyperbaric oxygen after leg amputation wounds heal
This study tests whether giving extra treatments with hyperbaric (pressure) oxygen after a leg amputation can improve healing or recovery. It’s meant for people whose amputation happened due to long-lasting infection or poor blood flow and who can attend follow-up visits.
OsloAges 18–90 - NCT06515093Recruiting
New skin grafts for diabetic foot and venous leg ulcers
This study tests two new skin graft products (PelloGraft for diabetic foot ulcers and SanoGraft for venous leg ulcers) to see if they heal wounds faster than standard care. If you have a hard-to-heal foot or leg ulcer, this trial may offer a new option.
Vista, CaliforniaAges 18 years+ - NCT07172893RecruitingPhase 4
Dermabind TL for diabetic foot ulcers
This trial tests a new wound dressing called DermaBind TL for people with diabetic foot ulcers. It aims to see if the dressing helps heal these wounds, which can be hard to treat.
DeLand, FloridaAges 18–80 - NCT07086443RecruitingPhase 4
Testing a new wound therapy for diabetic foot ulcers
This study tests a new wound therapy for diabetic foot ulcers that haven't healed with standard care. It aims to see if the therapy helps these ulcers heal better and faster.
Monroeville, PennsylvaniaAges 18 years+ - NCT05422248Recruiting
Testing a new oxygen treatment for hard-to-heal leg wounds
This study tests whether a new oxygen-based wound treatment is safe and workable for people with lower-leg wounds that are slow to heal. It may help improve healing by changing the wound environment, but it’s mainly focused on feasibility (whether the approach can be used).
Dunedin, OtagoAges 16 years+ - NCT06421961Enrolling by invitation
AI smartphone app for monitoring leg ulcers in PAD
This study tests a smartphone-based tool that uses artificial intelligence to help monitor hard-to-heal leg ulcers caused by poor arterial blood flow. The goal is to see if the tool can accurately assess wound healing at home.
GothenburgAges 18 years+ - NCT04210089Recruiting
Soft cast bandage for diabetic foot ulcers
This study tests whether a “total contact” soft cast bandage helps people heal diabetic foot ulcers. You may be asked to get your leg wrapped and have regular follow-up visits so the ulcer can be checked closely.
Minneapolis, MinnesotaAges 18 years+ - NCT06681428Recruiting
Amniotic tissue treatment for diabetic foot ulcers
This trial tests whether an amniotic tissue treatment can help heal chronic diabetic foot ulcers that haven't improved with standard care. It focuses on a single ulcer below the ankle that has been present for more than 4 weeks but less than a year.
Fresno, CaliforniaAges 18 years+ - NCT07360418Recruiting
Follow-up study for healed diabetic foot ulcers
This trial checks if diabetic foot ulcers that healed during an earlier study stay closed over time. You can join only if your ulcer fully healed in that previous trial.
Clinton Township, MichiganAges 18 years+ - NCT06560502Recruiting
Testing new treatments for diabetic foot and leg ulcers
This trial tests whether adding a special treatment (cellular acellular and matrix-like products) to standard wound care helps diabetic foot ulcers and venous leg ulcers heal faster. It may be an option if you have a diabetes-related foot ulcer that hasn't healed with standard care.
Circleville, OhioAges 21 years+ - NCT06674980Recruiting
Testing placenta-based wound treatment for diabetic and venous leg ulcers
This trial tests if adding a special placenta-based wound covering to standard care helps heal diabetic foot ulcers and venous leg ulcers faster. It's for people with wounds that haven't healed after standard treatment for at least 4 weeks.
Metairie, LouisianaAges 18 years+ - NCT06667752Recruiting
Antibacterial wound dressing for diabetic foot ulcers
This trial tests a new antibacterial wound dressing to see if it helps heal diabetic foot ulcers safely. It may be an option if your ulcer has been there for over 4 weeks and is not severely infected.
Tallinn, HarjuAges 18 years+ - NCT05762432Recruiting
Wound dressing study for certain diabetic foot ulcers
This study looks at a specific wound dressing in people with a non-infected diabetic foot ulcer that has nerve pain (neuropathic), poor blood flow (ischemic), or both. It may help you heal the ulcer and improve how the wound looks and progresses.
Airdrie, North LanarkshireAges 18 years+ - NCT06487780Recruiting
Preventing foot ulcers with a lifestyle program
This trial tests whether a lifestyle program can help people with diabetes avoid new foot ulcers. If you've healed from a foot ulcer in the last year, you may be able to join.
Downey, CaliforniaAges 21 years+ - NCT06721754Recruiting
Negative pressure therapy for diabetic foot ulcers
This study tests if a vacuum-like wound dressing (negative pressure wound therapy) helps heal diabetic foot ulcers after surgery. It may be a good fit if you have a foot ulcer needing surgery and are able to walk.
Oslo, NordbyhagenAges 18 years+ - NCT07073040Recruiting
Cold plasma therapy for diabetic foot ulcers with blocked arteries
This trial tests whether adding cold atmospheric plasma (a gentle gas treatment) to a standard procedure that opens blocked leg arteries can help diabetic foot ulcers heal better and faster.
Anshan, LiaoningAges 18–80 - NCT07198061Recruiting
Cold Plasma for Diabetic Foot Ulcers After Leg Artery Treatment
This study tests whether adding cold atmospheric plasma treatment to standard care helps heal foot ulcers in people with diabetes who have recently had a procedure to open blocked leg arteries. The goal is to see if this approach is safe and more effective than current care alone.
Anshan, LiaoningAges 18–80 - NCT07023965Enrolling by invitation
Long-term follow-up study for gene therapy in critical limb ischemia
This study follows up with people who previously took part in a clinical trial testing an experimental gene therapy for critical limb ischemia (severe leg pain or sores due to blocked arteries). It aims to see how well the treatment works over time. If you were in that earlier trial and received at least one dose, joining this follow-up could help researchers learn more about the therapy's lasting effects.
Beijing, Beijing MunicipalityAges 20–85 - NCT07768228RecruitingPhase 2
L-carnitine for healing diabetic foot ulcers
This study tests whether a supplement called L-carnitine can help diabetic foot ulcers heal faster. It is for people with type 2 diabetes who have mild to moderate foot ulcers and neuropathy (nerve damage in the feet).
Cairo, Cairo GovernorateAges 30–75
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Common questions
- Are there clinical trials for chronic wound of the lower limb (leg ulcer or foot ulcer)?
- Yes. Clin2 currently lists 180 recruiting chronic wound of the lower limb (leg ulcer or foot ulcer) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic wound of the lower limb (leg ulcer or foot ulcer) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic wound of the lower limb (leg ulcer or foot ulcer) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.