Clinical trials
Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer) clinical trials
Below are recruiting chronic wound of the lower limb (leg ulcer or foot ulcer) clinical trials, each written for real people, not researchers. We’re tracking 173 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04164641Recruiting
Test software-guided walking analysis to help prevent foot ulcers
This study checks whether a computer system that analyzes your walking can help change gait (how you walk) to reduce the chance of diabetic foot ulcers coming back or leading to amputation. It is meant for adults who have had a healed diabetic foot ulcer before.
Baltimore, MarylandAges 18–90 - NCT07465640Recruiting
Pulsed magnetic field therapy for diabetic foot ulcers
This trial tests a device called CRAD ULCER X-01 that uses gentle magnetic pulses to help heal diabetic foot ulcers. It may help people with a diabetic foot ulcer that is not too deep and is at an early stage.
Kuala LumpurAges 18 years+ - NCT06104969Recruiting
Biomarkers for active diabetic foot ulcers
This study is looking for people with diabetes who have an open foot or ankle ulcer. Researchers want to collect samples to find biomarkers, which are natural signs in the body that could help improve treatment and healing. It may be a good fit if you have a diabetic foot ulcer and are not currently in another drug trial for ulcers.
Tucson, ArizonaAges 18 years+ - NCT06124586Recruiting
Early angioplasty for diabetic foot ulcers
This trial tests if an early procedure to open blocked leg arteries (angioplasty) helps heal foot ulcers in people with type 2 diabetes. It aims to improve blood flow and prevent amputation.
DüsseldorfAges 18 years+ - NCT05313165Recruiting
Stent procedure for poor blood flow in the leg ulcers and gangrene
This trial tests a new minimally invasive procedure (placing a small stent) to improve blood flow to a severely threatened foot or lower leg. It may help people whose ulcers or gangrene are not treatable with standard bypass or other surgeries.
La Jolla, CaliforniaAges 18–95 - NCT07852338RecruitingPhase 3
Placental graft for diabetic foot ulcers
This trial tests a treatment made from placental tissue, called Bioxheal, which is placed on a diabetic foot ulcer to help it heal. It compares this treatment to standard care alone.
Boardman, OhioAges 18 years+ - NCT05132179Recruiting
Testing two antiseptic creams for diabetic foot ulcers
This study compares two topical (applied on the skin) antimicrobial agents—Dakin’s and Prontosan—to help heal diabetic foot ulcers. You may be eligible if you have a diabetic foot ulcer that has been present for at least 3 weeks and is large enough.
Uddevalla, TrollhattanAges 18–100 - NCT07831707Recruiting
Walking and attention study for people with one leg amputation
This study looks at how attention and surroundings affect walking in people with a lower leg amputation. It may help improve mobility and independence.
Richmond, VirginiaAges 18 years+ - NCT07798960RecruitingPhase 2
Light therapy for diabetic foot ulcers
This study tests whether shining a special light on diabetic foot ulcers can help them heal faster. It aims to find out if the treatment is safe and effective.
Teresina, PiauíAges 18 years+ - NCT07781917Recruiting
Comparison of two treatments for diabetic foot ulcers
This study compares two treatments for diabetic foot ulcers that haven't healed with standard care. It aims to see which treatment is more effective in helping these wounds close.
DhakaAges 18–75 - NCT03687580Recruiting
At-home laser treatment for diabetic foot ulcers
This trial tests whether an at-home low-level laser can help diabetic foot ulcers heal. You may be able to do treatments yourself or with a caregiver, but you must meet specific wound, circulation, and safety requirements.
Toronto, OntarioAges 18–95 - NCT07581145RecruitingPhase 3
Semaglutide for Faster Healing of Diabetic Foot Ulcers
This study tests whether a diabetes medication called semaglutide can help foot ulcers heal faster in people with type 2 diabetes. If it works, it could offer a new treatment option for a common and serious diabetes complication.
CopenhagenAges 18–90 - NCT07536373RecruitingPhase 3
Colchicine to prevent amputation after leg artery treatment
This study tests whether a medication called colchicine can help prevent amputation in people with severe leg blood flow problems who just had surgery or a catheter procedure to restore blood flow. Colchicine is an anti-inflammatory drug that may help protect the leg tissue after treatment.
Taipei, TaipeiAges 18 years+ - NCT06764953Recruiting
Amnion membrane graft for non-healing leg ulcers
This study tests a special amnion membrane graft to help heal chronic leg ulcers that haven't improved with standard care. The graft is placed on the wound to support healing, and results are compared with standard treatment alone.
Roanoke, VirginiaAges 18 years+ - NCT06767501Recruiting
Amnion graft for diabetic foot ulcers vs. standard care
This trial tests whether a special amnion membrane graft can help heal diabetic foot ulcers better than standard care alone. If you have a diabetic foot ulcer that hasn't healed after standard treatment, this study may offer a new option.
Roanoke, VirginiaAges 18 years+ - NCT07488247RecruitingPhase 3
Light-Activated Gel for Diabetic Foot Ulcers
This trial tests a gel containing a light-activated drug (chlorin E6) for diabetic foot ulcers. The gel is applied to the ulcer and then activated with a special light to help the wound heal. It may be a good option if you have a foot ulcer that hasn't healed in 6 weeks or more.
Karachi, SindhAges 18 years+ - NCT06852976RecruitingPhase 2
Gel treatment for diabetic foot ulcers study
This trial tests a new gel (MDI-1228-mesylate) applied to diabetic foot ulcers to see if it helps them heal faster than standard care alone. It is for people who have had a foot ulcer for at least 12 weeks and are already receiving standard treatment.
Durham, North CarolinaAges 18–75 - NCT07291817Recruiting
Negative pressure treatment for diabetic foot ulcers
This trial tests a device that uses gentle suction (negative pressure) to help heal diabetic foot ulcers. It may help people with poor blood flow in their legs who have not healed with other treatments.
SingaporeAges 21–99 - NCT06618612Recruiting
Wound matrix for diabetic foot ulcers
This study tests if a special wound dressing (collagen matrix with antimicrobial) plus standard care helps diabetic foot ulcers heal better than standard care alone. It's for people with diabetes who have a foot sore that hasn't healed for at least 4 weeks.
Clevland, OhioAges 18 years+ - NCT07188337Recruiting
Diabetic foot ulcer patient study
This study looks at the health records of people with diabetic foot ulcers to understand their characteristics. It may help improve care for future patients.
Gorgan, Outside of the USAges Any age - NCT07161830Recruiting
Skin repair treatment for diabetic foot ulcers
This study tests a special skin repair matrix for diabetic foot ulcers that are not healing well with standard care. The treatment may help the wound close and heal faster.
Evergreen Park, IllinoisAges 18 years+ - NCT07119983Recruiting
Stress ball for pain relief during diabetic foot wound cleaning
This study tests whether squeezing a stress ball during wound cleaning (debridement) can help reduce pain and distress for people with diabetic foot ulcers. If you're having this procedure for the first time and have mild pain or more, this simple technique may offer comfort.
Mersin, TarsusAges 18 years+ - NCT07109895Recruiting
Custom insoles with electrical stimulation for diabetic foot ulcers
This study tests whether custom-made insoles combined with a mild electrical stimulation device can help heal diabetic foot ulcers better than standard care. It may reduce pain and improve healing for people with early-stage foot ulcers.
Lahore, Punjab ProvinceAges 18 years+ - NCT07096934RecruitingPhase 1/Phase 2
Testing a new cell treatment for stubborn diabetic foot ulcers
This trial tests a new treatment using special skin cells grown into tiny spheres (spheroids) to help heal diabetic foot ulcers that have not healed with standard care. It aims to see if this treatment is safe and works better than usual care.
Coffs Harbour, New South WalesAges 18–80
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Common questions
- Are there clinical trials for chronic wound of the lower limb (leg ulcer or foot ulcer)?
- Yes. Clin2 currently lists 173 recruiting chronic wound of the lower limb (leg ulcer or foot ulcer) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic wound of the lower limb (leg ulcer or foot ulcer) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic wound of the lower limb (leg ulcer or foot ulcer) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.