Clinical trials
Congenital Heart Disease clinical trials
Below are recruiting congenital heart disease clinical trials, each written for real people, not researchers. We’re tracking 183 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06705543Recruiting
Genetic study of complex heart defects in unborn babies
This study looks at the genetic material in the fluid around the baby (amniotic fluid) and in the placenta to better understand complex heart defects in unborn babies. The goal is to find new clues that could help doctors care for these babies before and after birth.
BordeauxAges 18 years+ - NCT07114718Recruiting
Stent for babies with heart defect needing extra blood flow
This trial tests a special stent for babies with a heart defect that needs a temporary blood vessel to stay open. The stent is placed to help blood flow to the lungs until the baby can have a more permanent surgery.
Los Angeles, CaliforniaAges 1 minute–6 months - NCT07115108Recruiting
High-energy feeding for growth and brain development in infants with heart disease
This study tests a special high-energy formula for babies with congenital heart disease who are at nutritional risk. It aims to see if this feeding helps them grow and develop better before and after heart surgery.
Shanghai, Shanghai MunicipalityAges birth–6 months - NCT06969924Recruiting
How CRT works for adults with congenital heart disease
This study looks at how well cardiac resynchronization therapy (CRT) works for adults who were born with a heart defect. Researchers will review medical records to see if the therapy helps improve heart function.
Leiden, South HollandAges 18 years+ - NCT07092644Recruiting
Preeclampsia and baby heart defects: mother's heart study
This study looks at the link between preeclampsia (a pregnancy complication with high blood pressure) and a mother's heart health when her baby has a heart problem. The goal is to understand how the mother's heart adapts during pregnancy in these cases.
RomaAges 18 years+ - NCT07081711Recruiting
Testing new heart MRI technology in volunteers
This study is testing a new way to take pictures of the heart using MRI. It is looking for healthy volunteers to help make sure the technology works correctly.
Cleveland, OhioAges 18 years+ - NCT06861998Recruiting
Sleep help before heart surgery for infants and toddlers
This trial tests if helping young children with sleep problems before heart surgery can reduce confusion or agitation after surgery. It is for children ages 0 to 3 who have sleep issues and are scheduled for heart repair surgery.
BeijingAges 1 day–3 years - NCT07029230Recruiting
Blood test during heart surgery to predict heart failure in kids
This study looks at a substance called sST2 in the blood of children having heart surgery. The goal is to see if sST2 levels can help doctors predict heart failure after surgery.
Zurich, Canton of ZurichAges Up to 18 years - NCT06879431Recruiting
Sleep help before heart surgery for young children
This study tests if helping babies and toddlers with sleep problems sleep better before heart surgery can lower the risk of confusion or agitation after surgery. It is for children aged 0 to 3 years who have trouble sleeping and are scheduled for heart surgery.
BeijingAges 6–12 - NCT06952933Recruiting
Trauma and resilience in adults with congenital heart disease
This study surveys adults with congenital heart disease to understand how psychological trauma and resilience affect their health. You would complete online questionnaires about your experiences and coping.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06932081Recruiting
Study of SGLT2i in adults with congenital heart disease
This trial is a registry that follows adults with congenital heart disease who have started taking an SGLT2 inhibitor medication. The goal is to learn how well this treatment works for this group of patients.
Baltimore, MarylandAges 18 years+ - NCT02852031Recruiting
Care program for newborns needing the Norwood procedure
This trial focuses on improving care for babies born with certain complex heart conditions where only one pumping chamber works. It is meant for babies (including unborn babies) who are planned to have the Norwood procedure, which is a common early surgery.
Birmingham, AlabamaAges Up to 1.3 years - NCT06588426Recruiting
Skin punch biopsy collection for heart disease research
This trial collects a small skin sample (like a biopsy) from people with congenital heart disease. The samples help prepare for future clinical trials that may test new heart treatments.
Rochester, MinnesotaAges 18 years+ - NCT04467671RecruitingPhase 2
Tested new blood vessel graft for a heart surgery
This trial studies whether a newer “tissue-engineered” blood vessel graft is safe and works well in children who need a specific heart surgery connection outside the heart. It may help by offering a new type of graft, but your team will screen for size and medical factors first.
Columbus, OhioAges Any age - NCT06818760Recruiting
Remote monitoring for pregnant women with heart conditions
This study tests if a wrist wearable can safely monitor pregnant women with congenital heart disease. It aims to improve care during pregnancy, delivery, and after birth by tracking health data remotely.
Cleveland, OhioAges 18 years+ - NCT06776822Enrolling by invitation
DNS therapy for asymmetry after heart surgery in children
This trial tests whether a special physical therapy called DNS (Dynamic Neuromuscular Stabilization) can help children aged 6 to 18 who have body asymmetry (uneven movement or posture) after surgery for a congenital heart defect. Participation may improve their balance and muscle control.
PragueAges 6–18 - NCT06711666Recruiting
Maternal mental health and baby's brain in heart disease
This study looks at how a mother's mental health during pregnancy may affect the brain development of babies with a serious heart condition called critical cyanotic congenital heart disease (CHD). It aims to understand this link to improve support for families.
MarseilleAges Up to 50 years - NCT06690151Recruiting
Babies with heart defects and development support
This study looks at how a serious heart condition before birth may affect a baby's brain development. It follows babies and their parents to better understand and support these children as they grow.
Nantes, Loire AtlantiqueAges Any age - NCT06581484Recruiting
Improving care for adults with congenital heart disease
This study aims to improve care for adults with congenital heart disease. If you join, researchers will work to better understand your needs and help enhance your treatment.
San Francisco, CaliforniaAges 18 years+ - NCT06575270Recruiting
Study of skin color and pulse oximeters in children with heart disease
This trial checks how well pulse oximeters (devices that measure oxygen levels) work in children with congenital heart disease who have different skin colors. It aims to make sure these devices are accurate for all children during heart surgery.
New York, New YorkAges Up to 18 years - NCT06542120Recruiting
Child health body sounds study
This study looks at how well a computer system can check children's health by listening to body sounds, like those from the heart, lungs, or belly. It is testing an AI system to see if it works well as an extra check alongside regular medical care.
Wuhan, HubeiAges Up to 18 years - NCT06526195Recruiting
A study of CardioMEMS and HeartMate 3 for advanced heart failure
This trial tests if a combination of a tiny lung-artery pressure sensor (CardioMEMS) and a mechanical heart pump (HeartMate 3) is safe and effective for people with advanced heart failure. If you qualify, you'll either get the heart pump plus standard medical therapy, or continue with standard therapy alone and have your pressure monitored remotely.
Phoenix, ArizonaAges 18 years+ - NCT06431269Recruiting
Screening for developmental disorders in children with heart disease
This study is looking for children aged 1 to 5 years who have congenital heart disease and had heart surgery or a procedure in their first year. A special nurse will check for early signs of developmental delays, to see if this kind of screening is helpful for these children.
MontpellierAges 1–5 - NCT06434207Recruiting
Heart defect study in newborns to understand blood clots
This study looks at tiny particles from cells in newborns with heart defects to understand blood clot risks. It aims to find ways to prevent clots after heart surgery.
Boston, MassachusettsAges 1 day–1 week
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Common questions
- Are there clinical trials for congenital heart disease?
- Yes. Clin2 currently lists 183 recruiting congenital heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a congenital heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a congenital heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.