Clinical trials
Congenital Heart Disease clinical trials
Below are recruiting congenital heart disease clinical trials, each written for real people, not researchers. We’re tracking 186 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07115108Recruiting
High-energy feeding for growth and brain development in infants with heart disease
This study tests a special high-energy formula for babies with congenital heart disease who are at nutritional risk. It aims to see if this feeding helps them grow and develop better before and after heart surgery.
Shanghai, Shanghai MunicipalityAges birth–6 months - NCT07585175Recruiting
Moving from pediatric to adult heart disease care
This study helps doctors understand how to smoothly transition young people with heart problems they were born with from pediatric (children's) hospitals to adult care. It may help improve care coordination and outcomes as patients grow up.
Ottawa, OntarioAges 18 years+ - NCT06690151Recruiting
Babies with heart defects and development support
This study looks at how a serious heart condition before birth may affect a baby's brain development. It follows babies and their parents to better understand and support these children as they grow.
Nantes, Loire AtlantiqueAges Any age - NCT01192048Recruiting
Study genetics in congenital heart disease
This study looks at how genes may contribute to congenital heart disease. It may help researchers better understand causes and risk in families like yours.
Columbus, OhioAges Any age - NCT01653223Recruiting
Simvastatin to protect the heart during heart surgery
This trial looks at whether simvastatin (a cholesterol medicine) can help protect the heart during cardiac surgery. You might be invited if you’re having surgery for certain, non-complex heart conditions, but not if you have some specific related health problems.
Guangzhou, GuangdongAges 18 years+ - NCT02852031Recruiting
Care program for newborns needing the Norwood procedure
This trial focuses on improving care for babies born with certain complex heart conditions where only one pumping chamber works. It is meant for babies (including unborn babies) who are planned to have the Norwood procedure, which is a common early surgery.
Birmingham, AlabamaAges Up to 1.3 years - NCT02258724Recruiting
Adults with congenital heart disease in Swiss GUCH centers
This study is a national registry that collects health information from adults (age 18+) with congenital heart disease. It may help researchers better understand care and outcomes in people treated at specialized Swiss centers.
BaselAges 18 years+ - NCT03209583Recruiting
Test of fast-pacing therapy for congenital heart rhythm issues
This trial studies whether a device-based fast pacing therapy (called ATP) can better treat certain rapid heart rhythm problems in people born with a heart condition. It may help prevent or reduce episodes of atrial (upper-chamber) arrhythmias that occur despite having a pacing/defibrillator device.
Los Angeles, CaliforniaAges Any age - NCT02923440Recruiting
Donate DNA and help build a congenital heart study database
This study creates a DNA bank and a French database for babies and children with certain types of congenital heart defects, to better understand genetic causes. You’ll be asked to have a blood test and share consent, even though care can continue as usual at the study hospital.
MarseilleAges Any age - NCT07425132Recruiting
Non-invasive heart mapping for congenital heart disease
This trial tests a new, non-invasive way to create detailed 3D maps of the heart's electrical activity in people with congenital heart disease. It aims to help guide procedures like heart catheterization or device implantation, potentially making them safer and more personalized.
Madrid, MadridAges 18–80 - NCT07477197Recruiting
Heart Institute Biobank for Adult Congenital Heart Disease
This study collects blood and tissue samples and health information from adults with or at risk for congenital heart disease or related heart conditions. It aims to help researchers better understand these conditions and improve future treatments.
Cincinnati, OhioAges 16 years+ - NCT07483203Recruiting
Lung blood vessel health in people getting heart valve procedures
This study looks at how lung blood vessels work in people who are getting their heart valve fixed or replaced. It may help doctors understand and manage related lung issues.
Rochester, MinnesotaAges 18 years+ - NCT07524998Recruiting
Surgery outcomes for complex heart defects across ages
This study tracks how children and adults with complex heart defects fare after surgery. Researchers want to understand what surgical techniques work best at different ages and how patients recover long-term.
BeijingAges Any age - NCT07535203Recruiting
Heart Surgery Outcomes in Single-Ventricle Disease
This study follows children with a rare heart condition (univentricular heart) who need multiple surgeries, including a procedure called Fontan. Researchers want to understand how different blood-flow patterns after surgery affect long-term health and outcomes.
Jakarta, DKI JakartaAges Any age - NCT07556185Recruiting
Testing a home heart health monitoring app for kids
This study tests whether young people with heart conditions can use a home monitoring app called Medly to track their symptoms and weight. The app may help doctors catch problems earlier and keep kids healthier at home.
Toronto, OntarioAges 8–18 - NCT07424976Enrolling by invitation
Early brain injury detection after infant heart surgery
This study looks for early signs of brain injury in infants after heart surgery that uses a heart-lung machine. It aims to improve monitoring and care for babies with congenital heart disease.
LjubljanaAges 1 week–1 year - NCT07376785Enrolling by invitation
Can smartphones check heart sounds for birth defects?
This study tests whether a smartphone app can accurately detect inborn heart diseases by listening to heart sounds. Participation involves having your heart sounds recorded with a smartphone, which may help find problems earlier.
Hong KongAges 6 years+ - NCT06776822Enrolling by invitation
DNS therapy for asymmetry after heart surgery in children
This trial tests whether a special physical therapy called DNS (Dynamic Neuromuscular Stabilization) can help children aged 6 to 18 who have body asymmetry (uneven movement or posture) after surgery for a congenital heart defect. Participation may improve their balance and muscle control.
PragueAges 6–18 - NCT05979870Enrolling by invitation
AI-enhanced heart MRI for valve disease
This study uses artificial intelligence to improve MRI scans for people with aortic or pulmonary valve disease who are scheduled for valve surgery or a non-surgical valve procedure. It aims to help doctors better assess heart function before treatment.
Gothenburg, GothenburgAges 1 week–18 years - NCT05610787Enrolling by invitation
Testing a device that helps move an EXCOR pediatric heart pump
This trial studies an “active driving” system that controls the EXCOR pediatric heart pump. It’s meant for children who need a heart pump as a bridge to heart transplantation, to help the pump work more safely and effectively.
Los Angeles, CaliforniaAges Up to 21 years - NCT05101746Enrolling by invitationPhase 2/Phase 3
Nitric oxide to protect brain and kidneys in babies during heart surgery
This trial studies whether giving nitric oxide during heart-lung bypass surgery can help protect a baby’s brain and kidneys. If you qualify, the study team will check outcomes after surgery to see if benefits happen compared with usual care.
Nashville, TennesseeAges birth–1 year - NCT04141605Enrolling by invitation
Heart transplant candidates matched for better heart preservation
This study creates a worldwide registry and information database to help improve how donor hearts are preserved for transplant. If you are a heart transplant candidate, your details may be recorded to see what matching and preservation approaches work best.
Stanford, CaliforniaAges Any age - NCT04126018Recruiting
MRI scan comparison for certain leaking or narrowed heart valves
This trial studies how well different MRI images can assess heart valve problems—like leaking (regurgitation) or narrowing (stenosis). It may help doctors get clearer information, especially in people who may not respond well to cardiac resynchronization therapy (CRT).
Cleveland, OhioAges 18–90 - NCT06932874RecruitingPhase 4
Metformin for diabetes with heart disease
This trial tests a long-acting metformin pill in people with both type 2 diabetes and coronary heart disease. It aims to see if metformin can safely help control blood sugar in this specific group.
Beijing, Beijing MunicipalityAges 30–75
Hear when a new Congenital Heart Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for congenital heart disease?
- Yes. Clin2 currently lists 186 recruiting congenital heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a congenital heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a congenital heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.