Clinical trials
Congenital Heart Disease clinical trials
Below are recruiting congenital heart disease clinical trials, each written for real people, not researchers. We’re tracking 183 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07176507Recruiting
Study of multiple and mixed heart valve disease
This study looks at people who have two or more heart valve problems that are moderate to severe. It aims to learn more about this condition and how to best manage it.
LilleAges 18 years+ - NCT06932874RecruitingPhase 4
Metformin for diabetes with heart disease
This trial tests a long-acting metformin pill in people with both type 2 diabetes and coronary heart disease. It aims to see if metformin can safely help control blood sugar in this specific group.
Beijing, Beijing MunicipalityAges 30–75 - NCT07033676Enrolling by invitation
Study of a blood marker for heart damage from high blood pressure
This trial looks at a substance in your blood called miR-455-5p to see if it can help doctors understand heart changes caused by high blood pressure. It involves people who have had high blood pressure for over a year and may have some heart symptoms.
Shenzhen, GuangdongAges 18 years+ - NCT04126018Recruiting
MRI scan comparison for certain leaking or narrowed heart valves
This trial studies how well different MRI images can assess heart valve problems—like leaking (regurgitation) or narrowing (stenosis). It may help doctors get clearer information, especially in people who may not respond well to cardiac resynchronization therapy (CRT).
Cleveland, OhioAges 18–90 - NCT05809310Recruiting
Stenting branches to improve blood flow after certain heart repairs
This study looks at whether placing a small tube (stent) in a branch pulmonary artery can improve blood flow and heart function after specific childhood heart surgeries. It is meant for people who have d-TGA after ASO, or have ToF or TA, and need a branch PA intervention.
AmsterdamAges 8 years+ - NCT05658965Recruiting
EEG monitoring after early heart surgery in infants
This study looks at whether early brain-wave testing (EEG) around the time of heart surgery in very young babies can predict later learning and development issues. It may help doctors identify children who need extra support sooner.
Lille, Hauts-de-FranceAges 1 day–1 year - NCT05386173Recruiting
Tests fetal aortic valve balloon surgery for severe narrowing
This trial studies whether doing a procedure before birth to open a baby’s aortic valve improves outcomes. It compares this approach in a specific group of pregnancies with severe heart flow problems seen on ultrasound.
San Francisco, CaliforniaAges 5 months–7 months - NCT07217522Recruiting
Genetics of pulmonary hypertension study
This study looks at the genes that may be linked to pulmonary hypertension. By providing a saliva sample and filling out a health survey from home, you can help researchers learn more about this condition.
Piscataway, New JerseyAges 18 years+ - NCT07742046Enrolling by invitation
Heart blood flow scan for congenital heart disease
This study tests a new MRI technique to measure blood flow in the heart without invasive procedures. It may help doctors better understand and manage congenital heart conditions.
LausanneAges 16 years+ - NCT04464655Recruiting
10-minute heart MRI protocol for people with heart conditions
This study uses a short, 10-minute heart MRI to check how well it works for people who need a clinically indicated heart scan. It may help streamline heart MRI testing, making exams faster while still providing useful heart information.
Montreal, QuebecAges 18 years+ - NCT03837574Recruiting
Registry for people with Tetralogy of Fallot and a defibrillator
This is a national registry that collects information about people with Tetralogy of Fallot who have an implantable defibrillator. It helps researchers better understand outcomes and care needs in this specific group.
ParisAges 18 years+ - NCT05865119Recruiting
Best treatment approach for a certain heart wall defect
This study looks at the best treatment plan for people with a specific type of hole in the heart wall that affects the right side of the heart. It may help doctors choose an approach based on how well it works for patients who need treatment.
BordeauxAges 12 years+ - NCT07764510Enrolling by invitation
Heart-to-heart support for teens with congenital heart disease
This study tests a support program designed to help teens with congenital heart disease feel better and manage their health. It may improve emotional well-being and heart health.
Columbus, OhioAges 12–18 - NCT06611787Recruiting
Registry study for congenital heart disease
This study collects information from people with congenital heart disease (a heart problem you're born with) over their entire life to better understand the condition and improve future care.
Beijing, Beijing MunicipalityAges Any age - NCT07732244Recruiting
Testing a wireless brain oxygen monitor in the NICU
This study is testing a new wireless device that monitors oxygen levels in the brain. It is for babies already using a similar wired monitor, to see if the wireless version works just as well.
Montreal, QuebecAges Any age - NCT07564882Recruiting
Music and Mobile Apps to Help Babies With Heart Surgery Pain
This study tests whether music and a mobile app can help reduce pain and stress in babies aged 2–12 months who have had heart surgery. Researchers will measure pain levels and vital signs like heart rate and breathing.
AnkaraAges 2 months–1 year - NCT07559253Recruiting
Heart Care Transition Education Led by Nurses or Doctors
This study tests whether nurse-led or doctor-led education helps young people with congenital heart disease (a heart condition present from birth) transition from pediatric to adult care. The goal is to make this transition smoother and more accessible for all patients, including those with disabilities.
Madison, WisconsinAges 12–26 - NCT06775639Recruiting
Can we skip a heart artery test before surgery?
This study looks at whether people with adult congenital heart disease can skip a pre-surgery artery test (coronary angiography) if they already had a CT scan. If you qualify, you might help doctors find safer, simpler ways to prepare for heart surgery.
BolognaAges 18 years+ - NCT07466745Recruiting
New Pulmonary Valve Study for Kids Needing Replacement
This study tests a new type of replacement valve for children who need a new pulmonary valve (the valve between the heart and lungs). Researchers want to see if the valve works safely and well in real-world use.
Los Angeles, CaliforniaAges 1.5 years–16 years - NCT07414251Recruiting
Preparing children for heart procedures
This study looks at how children prepare for heart surgery or a heart catheterization. It will ask families to fill out questionnaires to help improve preoperative care.
Berlin, State of BerlinAges Up to 18 years - NCT07405333Recruiting
Coughing exercises vs breathing device after heart surgery in children
This study compares simple coughing exercises with a breathing device (incentive spirometry) to help children recover lung function faster after heart surgery. It may help reduce complications and shorten hospital stays.
Baghdad, Baghdad GovernorateAges 6–18 - NCT07375602Recruiting
AI tool to predict complications after VSD closure in children
This study uses artificial intelligence to predict complications in children who have had a specific type of hole in the heart (called a perimembranous ventricular septal defect) repaired with a catheter-based procedure. The goal is to help doctors better identify which children might have problems after the procedure.
Shanghai, Shanghai MunicipalityAges Up to 18 years - NCT07356778RecruitingPhase 4
Study of sotatercept for Eisenmenger syndrome patients
This trial tests a new drug called sotatercept for people with Eisenmenger syndrome or a related heart defect that hasn't been repaired. It may help if current treatments aren't working well enough.
Fukuoka, Not Required For This CountryAges 18 years+ - NCT07255144Recruiting
Ultrafast ultrasound imaging for children's heart conditions
This study tests a new, faster ultrasound technique to see heart structure and blood flow in children with or without congenital heart disease (CHD). It aims to improve imaging without risk, using a short scan during a regular check-up.
Pessac, FranceAges Any age
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Common questions
- Are there clinical trials for congenital heart disease?
- Yes. Clin2 currently lists 183 recruiting congenital heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a congenital heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a congenital heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.