Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 731 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06864234RecruitingPhase 4
Beta-blockers for chest pain without blocked arteries
This trial tests if beta-blocker medication improves blood flow and reduces resistance in the tiny blood vessels of the heart in people who have chest pain but no major blockages in their arteries.
Aalst, FlandersAges 18 years+ - NCT07019350Recruiting
Smart stenting for heart artery branch blockages
This trial tests a new way to treat complex blockages in heart arteries where a side branch is also narrowed. It uses a drug-coated balloon to open the side branch, aiming to improve blood flow and reduce the need for repeat procedures.
GwangjuAges 19 years+ - NCT07439133RecruitingPhase 3
Comparing new heart scan with standard tests for coronary disease
This trial is testing a new imaging agent called XTR004 to see if it can accurately find blockages in the heart's arteries. If you have suspected or confirmed stable coronary heart disease, this study may offer a less invasive way to diagnose your condition.
BeijingAges 18–80 - NCT07476040Recruiting
Better care for new stable chest pain
This trial tests a new way to manage stable chest pain that started recently. It aims to improve diagnosis and treatment for people suspected of having coronary artery disease.
AugsburgAges 30 years+ - NCT06231966Recruiting
High-dose statin combo vs. standard statin for artery disease
This trial compares a high-dose combination of rosuvastatin (a statin) and ezetimibe (another cholesterol-lowering drug) versus a standard rosuvastatin-only approach for people with peripheral artery disease (narrowed leg arteries) or widespread artery disease. The goal is to see which strategy better lowers LDL cholesterol and reduces heart and limb risks.
SeoulAges 19–80 - NCT07193693Recruiting
Study on why doctors don't use heart imaging during stent placement
This study looks at reasons doctors may or may not use a special camera inside the heart arteries (called OCT or IVUS) during a procedure to open blocked arteries. It may help understand how to improve care for people with complex blockages.
BergamoAges 18 years+ - NCT06956911Enrolling by invitation
Low-resistance exercise with blood flow restriction after heart surgery
This trial tests if gentle arm exercises with a special blood pressure cuff can help men recover their lung function after heart surgery. It may be an option for those who are stable and ready to follow simple instructions.
Cairo, Cairo GovernorateAges 45–60 - NCT05884008Recruiting
Using CT heart scans and AI to study plaque function
This study looks at people who had a heart attack and had a special CT scan (CT angiography) before or during the years leading up to it. Researchers will use the scan and computer analysis (AI) to better understand heart plaque and how it may relate to heart attacks.
Cangzhou, HebeiAges 18–80 - NCT06076551Recruiting
Sex differences in small blood vessel problems of the heart
This study looks at how small blood vessels in the heart work differently in men and women who have chest pain but no major blockages in their main heart arteries. The goal is to better understand and treat these smaller vessel issues.
SeoulAges 20–80 - NCT06558474Recruiting
Optimizing angioplasty with balloon expansion after stent placement
This trial looks at a technique called post-dilatation, where a balloon is used after placing a stent to make sure it's fully open. It may help people who are having angioplasty (a procedure to open blocked heart arteries). Doctors want to see if using this step more often leads to better results.
Eindhoven, North BrabantAges 18 years+ - NCT03563417Recruiting
CTO treatment vs medicines after heart scan
This trial studies whether opening a blocked coronary artery (a CTO) helps people more than staying on the best available heart medicines after an initial 3-month treatment period. It uses heart imaging to confirm there is reduced blood flow in the area supplied by the blockage.
Aarhus NAges 18 years+ - NCT07772570Recruiting
Studying blood markers in coronary artery disease
This study collects blood samples and images from patients with heart muscle damage or those undergoing coronary angiography. The goal is to find new biomarkers that could improve diagnosis and treatment of coronary artery disease.
OxfordAges 18–90 - NCT04709900Recruiting
Tests for stable chest pain using heart scans and pressure measurements
This trial studies how well different heart tests (imaging the blood flow and measuring blood pressure in the heart) work for people with stable chest pain. It may help guide safer, more accurate evaluation when you are not having a heart attack.
CopenhagenAges Any age - NCT05527717RecruitingPhase 4
PCI vs strategy for heart attack shock needing ECMO
This study looks at the best way to reopen blocked heart arteries (using a stent procedure) in people who had a heart attack complicated by severe shock and need a life-support machine called VA-ECMO. It may help improve outcomes by testing which revascularization approach works best for multi-vessel blockages.
SeoulAges 19 years+ - NCT06114615Recruiting
Remote monitoring after heart treatment to prevent future events
This trial tests whether digital tools can help monitor patients after a stent procedure to lower the chance of another heart problem. It aims to make follow-up care easier and more effective.
Sacramento, CaliforniaAges Any age - NCT07231939Recruiting
Testing diabetes drugs to protect kidneys after heart procedures
This study is testing whether a class of diabetes medicines called SGLT2 inhibitors (specifically empagliflozin or dapagliflozin) can prevent kidney injury after heart procedures that use contrast dye.
BydgoszczAges 18 years+ - NCT05700877RecruitingPhase 4
Screening and treatment for silent heart artery disease in type 2 diabetes
This trial tests a screening and intervention approach for “silent” coronary artery disease (heart artery narrowing without major symptoms) in people with type 2 diabetes. It may help prevent future heart problems by finding higher-risk cases early and starting the right treatment plan.
OdenseAges 55–75 - NCT05824520Recruiting
CT blood-flow test guided treatment versus usual care
This trial compares a treatment plan guided by a special CT scan measurement of blood flow (called CT-derived FFR) versus standard medical therapy. It may help doctors choose the safest, most effective treatment based on how restricted blood flow looks on CT.
Hangzhou, ZhejiangAges 18 years+ - NCT06541132Recruiting
Liver fat and heart artery narrowing study
This study looks at whether the amount of fat in your liver, seen on an ultrasound, is linked to the severity of narrowing in your heart arteries. If you had a heart catheterization (angiography) and an abdominal ultrasound, your data may help researchers understand this connection.
Chongqing, Chongqing MunicipalityAges 18–90 - NCT07068490Recruiting
Potassium blocker study for heart stent patients
This study looks at whether a type of stomach acid medication called PCAB can help people who have had a heart stent and take blood thinners. It checks if PCAB is safe and reduces stomach bleeding.
SeoulAges 18 years+ - NCT02792075Recruiting
Study heart artery narrowing seen on special imaging
This study follows people who already have a heart artery imaging test to understand what the imaging means for future heart outcomes. It may help doctors predict prognosis and guide treatment for coronary narrowing.
Seoul, Songpa-guAges 19 years+ - NCT04279496Enrolling by invitation
CT heart scan registry to track outcomes over time
This is a research registry that follows people who are already getting a CT scan of their heart arteries for medical reasons. It aims to better understand how these scans relate to future heart outcomes, while collecting follow-up health information.
Charlottesville, VirginiaAges 18 years+ - NCT06104007Recruiting
Genoss balloon for narrowed heart stents
This study follows patients who have already received a special drug-coated balloon (Genoss® DCB) to treat a re-narrowed heart stent. It aims to see how safe and effective the balloon is in the long term.
SeoulAges 19 years+ - NCT06529848Recruiting
Exercise for heart symptoms with clear arteries
This trial tests if exercise training can help people who have chest pain or shortness of breath even though their main heart arteries are not blocked. It focuses on those with small vessel disease in the heart, also known as INOCA.
CopenhagenAges 50 years+
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 731 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.