Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 731 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05369442Recruiting
Blood-thinner plan study for people with high bleeding risk after PCI
This trial studies which blood-thinner (antiplatelet) strategy is safest and most effective for people at high risk of bleeding after a procedure called PCI. It also looks at longer-term outcomes and whether adjusting treatment can improve safety without losing heart protection.
Sichuan, SichuanAges Any age - NCT05427084RecruitingPhase 2/Phase 3
Canagliflozin to reduce inflammation in heart artery disease
This trial tests canagliflozin to see if it lowers “vascular inflammation” in people with diabetes and stable coronary artery disease. It may help reduce harmful inflammation signals that can raise future heart risk.
Ottawa, OntarioAges 18 years+ - NCT05427370Recruiting
Compare bypass or stent treatment in weak heart patients
This study compares two ways to restore blood flow to the heart—bypass surgery (CABG) or stent procedure (PCI)—in people with a weak pumping heart. It looks at which approach works best when the heart muscle is not pumping well and there are multiple blocked heart arteries.
Los Angeles, CaliforniaAges 18 years+ - NCT05438121Recruiting
Tests a drug-coated balloon to stabilize clogged heart arteries
This trial studies whether a drug-coated balloon can better treat new, narrowed spots in multiple coronary arteries and “stabilize” the plaque. It may help improve blood flow after a procedure called balloon angioplasty for selected patients.
Ansan-si, Gyeonggi-doAges 18–85 - NCT05461729Recruiting
Testing a heart rehab timing prediction tool after a heart attack
This study follows people with coronary artery disease who are starting a structured heart rehabilitation program after a heart attack or heart procedures. The trial tests whether it can predict and improve the right timing or planning for cardiac rehab.
Ennepetal, North Rhine-WestphaliaAges 18 years+ - NCT05470335Recruiting
Nurse-led heart procedure setup for suspected heart artery disease
This study checks whether a nurse-led technique for placing a sheath (a small tube used during a heart test/procedure) works safely in people suspected of blocked heart arteries. If you qualify, your care team will guide the process and compare how it goes with standard approaches.
Roskilde, DanmarkAges 18 years+ - NCT05487612Recruiting
MiECC heart-lung machine vs standard bypass during heart surgery
This trial compares a newer heart-lung machine setup (MiECC) with the usual bypass technique during certain heart operations. It may help see whether MiECC changes outcomes like the need for blood transfusions or recovery after surgery.
TorontoAges 18–85 - NCT05488665Recruiting
Two-stent approach comparison for new bifurcation heart blockages
This study compares two different ways of placing two drug-eluting stents for new (de novo) coronary artery blockages that split into two branches. It may help doctors choose the safest, most effective technique for patients with specific coronary anatomy.
SeoulAges 19 years+ - NCT05618353RecruitingPhase 4
Colchicine before surgery to lower heart and inflammation complications
This trial tests whether taking colchicine around the time of surgery can reduce bad events after surgery in people at higher heart risk. It focuses on helping prevent complications related to inflammation after an operation.
Birmingham, AlabamaAges 18 years+ - NCT05632432Recruiting
Heart tissue grafts to help the heart after surgery
This trial tests whether transplanting tiny heart “micrografts” from the left heart chamber area can improve heart function after cardiac surgery. It is meant for people with weakened heart pumping and heart failure symptoms despite medicine.
Helsinki, UusimaaAges 18–75 - NCT05681702RecruitingPhase 4
Personalizing medicines to reduce bleeding after stent procedure
This trial studies ways to reduce bleeding in people after a stent procedure (PCI) who have been taking two anti-platelet medicines (aspirin plus prasugrel or ticagrelor) for a set amount of time. It may help find a safer plan for preventing blood clots while lowering bleeding risk.
Jacksonville, FloridaAges 18 years+ - NCT05704296Recruiting
Two bypass techniques using leg vein and chest artery
This study compares two ways of using a leg vein and an artery from your chest during coronary artery bypass surgery. It may help doctors learn which approach works best for making the new blood pathways to your heart.
SeoulAges 19 years+ - NCT05759676Recruiting
Diabetes and a new drug-free heart stent after angioplasty
This trial tests whether a polymer-free amphilimus-eluting stent is safe and works well for people with diabetes after a recent heart blockage procedure. It may help improve how well the artery stays open, while tracking side effects over time.
SeoulAges 19 years+ - NCT05762952RecruitingPhase 1
Dapagliflozin study for heart micro-blood-flow symptoms in women
This early-phase study tests whether dapagliflozin can improve tiny blood-vessel function in women who have heart-ache-like symptoms but no major blockage on heart scans. If it works, it may help symptoms related to “microvascular” heart circulation problems.
Charlottesville, VirginiaAges 18–99 - NCT05786131Recruiting
Stent treatment: fix all blocked arteries vs culprit only
This trial compares two ways of doing a stent procedure in people who had an NSTEMI heart attack: fixing all significant blockages versus fixing only the “culprit” blockage. It may help find which approach is safer and more effective for preventing complications.
GrazAges 18 years+ - NCT05936606Recruiting
Personalized blood thinner choice after stent placement
This trial tests whether tailoring anti-platelet (blood clot prevention) treatment can better protect people at higher risk of heart or blood-vessel problems after a drug-eluting stent. It may help prevent future clots and complications, especially in patients with certain high-risk health conditions or complex stent/scar tissue features.
SeoulAges 19–80 - NCT05981911Recruiting
Study of Xience Skypoint stents in everyday heart care
This trial is checking how well Xience Skypoint stents work and how safe they are for people who need them to open blocked heart arteries. It's for patients getting these stents as part of their normal treatment.
SeoulAges 19 years+ - NCT06014060Recruiting
Shorter vs. longer blood thinner therapy after stenting for high Lp(a)
This trial compares 12 months versus 24 months of dual antiplatelet therapy (two blood thinners) after a stent placement in people with high lipoprotein(a) levels. It aims to see if longer treatment reduces heart risks without increasing bleeding.
Beijing, Beijing MunicipalityAges 18–75 - NCT06068764RecruitingPhase 4
Comparing Two Anesthesia Drugs for Bypass Surgery
This study compares two common anesthesia medicines (etomidate and propofol) for patients having planned coronary artery bypass surgery. The goal is to see which medication works better for your heart and recovery.
Hartford, ConnecticutAges 18–90 - NCT06075160Recruiting
RFR-guided heart artery treatment for moderate blockages
This trial uses a special pressure wire called RFR to help doctors decide whether a stent is needed for a moderate heart artery blockage. It aims to make sure only the blockages that really need treatment get stented, which may reduce unnecessary procedures.
Bucheon-si, Gyeonggi-doAges 20–90 - NCT06179212Recruiting
Comparing exercise tests for men and women with heart disease
This study compares two different exercise test methods to see which works better for men and women with heart disease. The goal is to find a test that can help doctors design better exercise programs for you.
Ottawa, OntarioAges 18 years+ - NCT06205810Recruiting
Complete study on heart artery blockages
This trial looks at people with a blockage in a heart artery of 50% or more. It tests a new way to check the blockage using a special CT scan. This could help decide the best treatment to prevent future heart problems.
Aalst, Oost-VlaanderenAges 18 years+ - NCT06258681Recruiting
Breathing exercise device for recovery after heart surgery
This trial tests a new breathing exercise device designed to help your lungs recover after heart surgery. It may make your breathing easier and speed up your return to daily activities.
Istanbul, IstanbulAges 40–65 - NCT06302777Recruiting
Main image registry for heart artery imaging
This study is tracking patients who receive a special type of imaging (like an ultrasound) on their heart arteries before a procedure. It aims to learn more about how this imaging helps guide care.
Frankfurt am Main, HesseAges 18 years+
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 731 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.