Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 713 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05427084RecruitingPhase 2/Phase 3
Canagliflozin to reduce inflammation in heart artery disease
This trial tests canagliflozin to see if it lowers “vascular inflammation” in people with diabetes and stable coronary artery disease. It may help reduce harmful inflammation signals that can raise future heart risk.
Ottawa, OntarioAges 18 years+ - NCT07198529Recruiting
Short blood thinners after stenting for stable angina
This trial is testing a way to shorten the time you need to take blood thinners after getting a specific type of heart stent. It uses a special camera (OCT) inside the artery to help decide if stents are placed well enough to allow less time on dual antiplatelet therapy.
Seoul, Gurodong-ro, Guro-guAges 19 years+ - NCT07195968Enrolling by invitation
Comparing nitroglycerin and saline for heart artery testing
This trial compares two ways to test blood flow in the heart arteries: one uses a medicine called nitroglycerin, and the other uses salt water. It may help people with partial blockages (50-90%) in their heart arteries, especially if they have not had a recent serious heart attack.
Hsinchu, SelectAges 21 years+ - NCT06790836Recruiting
CT scan vs. invasive test for heart artery blood flow
This study looks at how well a special CT scan (FFR CT) matches the results of a more invasive wire test (invasive FFR) for measuring blood flow in heart arteries. It may help doctors use CT scans more confidently instead of always needing the invasive procedure.
Birmingham, West MidlandsAges 18 years+ - NCT07169201Recruiting
CT scan for heart in people with diabetes or heart disease
This study uses a special CT scan to look at your heart more closely. It may help people with known or suspected heart problems or type 2 diabetes.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07158307Enrolling by invitation
Studying a new balloon treatment for small heart arteries
This trial tests a special balloon coated with medicine to treat blocked small arteries in the heart. It may help people who have new blockages and are getting a procedure to open those arteries.
UlsanAges 19 years+ - NCT07133984Recruiting
Heart imaging study for patients with low heart function and coronary artery disease
This study uses cardiac MRI to look at the heart in people with weakened heart muscle and blocked heart arteries. It may help doctors improve treatments like bypass surgery or stents.
Brooklyn, New YorkAges 18 years+ - NCT06821191RecruitingPhase 4
Safer blood thinner plan after heart stent
This trial is testing whether lowering the dose of your current blood thinner or switching to a different one (clopidogrel) is safer and works just as well after you've had a stent placed. It's designed for people who are already on two blood thinners and are doing well.
Jacksonville, FloridaAges 18 years+ - NCT07048808RecruitingPhase 2
Gene therapy for chronic chest pain
This trial tests a new gene therapy (XC001) delivered through a thin tube into your heart's blood vessels. It aims to grow new blood vessels to relieve chest pain in people with chronic angina who have no other treatment options.
Birmingham, AlabamaAges 18–85 - NCT07591987Recruiting
Breathing Techniques to Reduce Shortness of Breath After Heart Surgery
This study tests whether special breathing exercises can help reduce shortness of breath and improve heart and lung function in patients recovering from open-heart surgery. You would learn and practice these breathing techniques before and after your surgery.
Baghdad, Baghdad GovernorateAges 18–75 - NCT07039812Recruiting
Virtual Reality for Pain During Dressing Changes After Heart Surgery
This study tests if using virtual reality or an eye mask during wound dressing changes can help reduce pain and anxiety after coronary artery bypass surgery. It aims to find a drug-free way to make dressing changes more comfortable.
Istanbul, MarmaraAges 18–65 - NCT07035106Recruiting
Using wearables to track recovery after ICU
This study tests if a wearable device and health summaries can help people recover after a stay in the intensive care unit (ICU). It is for people who have diabetes or heart problems and left the ICU within the last 2 years.
ViennaAges 18–65 - NCT06993636Recruiting
Study of rivaroxaban in Chinese children with large heart artery bulges
This trial is testing the drug rivaroxaban in children aged 2 to 17 who have large bulges (aneurysms) in their heart arteries after Kawasaki disease. It aims to see how the drug works in the body to prevent blood clots.
Shanghai, Shanghai MunicipalityAges 2–18 - NCT06995183Recruiting
Heart CT scan for relatives with high or low Lp(a)
This study uses a heart CT scan to look for early signs of heart disease in first-degree relatives of people with high or low Lp(a). It aims to find hidden risks before symptoms start.
Amsterdam, North HollandAges 50 years+ - NCT06969547Recruiting
Heart muscle coordination and microvessel function SPECT study
This study uses a special heart scan (SPECT) to look at how well the heart muscle is squeezing and how well the tiny blood vessels in the heart are working. It may help doctors understand why some people have chest pain even when their main arteries are not blocked.
TomskAges 18–75 - NCT07610538Recruiting
Low-dose IL-2 study after heart bypass surgery
This study tests whether a low dose of a natural immune-boosting protein (IL-2) given after heart bypass surgery can help reduce heart damage. The treatment aims to activate special immune cells that protect heart tissue.
Cambridge, CambridgeshireAges 18 years+ - NCT06908499Recruiting
Long-term follow-up of a stent study for chronic total occlusions
This study looks at the long-term (10-year) outcomes of a specific stenting technique for patients with a chronic total occlusion (a complete blockage that has been there for at least 3 months) in a major heart artery. It aims to see how well the procedure works over time.
Pune, MaharashtraAges 19 years+ - NCT06898827Enrolling by invitation
Virtual reality distraction therapy for cardiac rehab
This trial tests whether using virtual reality (VR) during cardiac rehabilitation can help distract you from discomfort or anxiety. If you have a heart condition or have had a heart event and are starting rehab, you may be able to join.
MsidaAges 40 years+ - NCT06839755Recruiting
Stress echo's positive value in heart health
This study looks at how well a stress echocardiogram (heart ultrasound during exercise or medication) predicts future health in people who have some sign of reduced blood flow to the heart. The goal is to confirm that a positive stress echo is a good sign for guiding next steps.
Athens, AtticaAges 18–100 - NCT06820970Recruiting
Combined therapy for heart artery blockages that weren't fully opened
This trial tests if combining a new heart procedure with a special type of therapy called mindfulness therapy can help prevent heart problems in people with coronary artery disease that could not be fully fixed with stents or surgery.
Zhengzhou, HenanAges 18 years+ - NCT06740396Recruiting
Depression in heart disease patients in Baghdad
This study looks at how common depression is in people with coronary artery disease and how severe it is. If you have heart disease and are being treated at a hospital in Baghdad, you can help doctors understand the link between heart health and mental health.
BaghdadAges 18 years+ - NCT06705023RecruitingPhase 2
Fat-derived cell therapy for heart failure
This study tests whether taking a small amount of your own belly fat (through liposuction), processing it, and injecting the cells back into your heart can improve heart function in people with chronic heart failure due to blocked arteries. The trial is for patients whose heart pumps weakly (ejection fraction of 40% or less) and who are already on standard medications.
AstanaAges 21–80 - NCT06691191RecruitingPhase 4
Switching to a single blood thinner after heart stent
This trial tests if people who have been on two blood thinners (aspirin plus prasugrel or ticagrelor) for at least 90 days after getting a heart stent can safely switch to just one of those blood thinners. It aims to see if taking only one pill is as safe and effective as taking two.
Jacksonville, FloridaAges 18–75 - NCT06662500Recruiting
Shockwave balloon for hard heart blockages trial
This trial tests a new balloon catheter that uses sound waves to break up hard calcium blockages in heart arteries. It may be an option for people with stable chest pain or who have recovered from a recent heart attack, and who have a single, tough blockage.
La Jolla, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 713 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.