Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05140434Recruiting
Check whether exercise heart tests help diagnose artery blockage
This study looks at whether an “exercise heart test” can better diagnose blockage in the heart’s coronary arteries. Participants may also have a heart scan or imaging test for comparison, within a short time window.
Corbeil-Essonnes, FranceAges 18 years+ - NCT05208749Recruiting
Shockwave or rotablation for calcified heart artery blockages
This study tests two ways to treat tightly calcified coronary (heart) artery blockages during a procedure to open the vessel. It may help improve how well the blockage can be widened and treated when standard balloon treatment is not enough.
Leuven, BrabantAges 18 years+ - NCT05230446Recruiting
Testing full stent treatment for heart artery blockages
This study looks at how well doctors can treat multiple blocked heart arteries using a specific drug-eluting stent, aiming to fully open them. It may help patients whose blockage pattern fits the study, but it does not include certain high-risk or special cases.
Rotterdam, South HollandAges 18–85 - NCT05248165Recruiting
Heart artery disease patients having stent placement
This study enrolls adults with blocked heart arteries who need a procedure called PCI (stent placement). It collects real-world information to help understand and improve care for people like you.
NaplesAges 18 years+ - NCT05250557Recruiting
Study heart blood-flow measurements to predict outcomes in coronary disease
This study looks at a specific heart blood-flow measurement taken during a coronary procedure to see how well it predicts future outcomes. If you had a successful pressure measurement called FFR with a tracing, your results may be analyzed to understand risk and prognosis.
SeoulAges 20 years+ - NCT05329285Recruiting
Compare bypass or stent for heart weakness from blocked arteries
This study compares two ways to improve blood flow in people with weakened heart pumping (ischemic cardiomyopathy): bypass surgery (CABG) versus stent treatment (PCI). It aims to see which approach works better when the heart still has enough at-risk muscle and when best medical therapy is already started.
GothenburgAges 18 years+ - NCT05337319Recruiting
Registry for people in the hospital with coronary artery disease
This study keeps a careful record of what care people with coronary artery disease receive while they are hospitalized. It may help doctors improve future treatment by showing what is happening in real-world practice.
BeijingAges 18 years+ - NCT05346068Recruiting
Compare two balloon types for calcium-heavy blocked heart arteries
This trial studies whether one type of balloon works better than another for treating badly calcified (hardened) coronary artery blockages. If you qualify, you would be randomly assigned to get the tested balloon treatment during your heart procedure.
LucerneAges 18 years+ - NCT05347069RecruitingPhase 4
Aspirin study for people with stable heart artery disease
This trial tests whether daily aspirin is safe and effective for people who have stable (chronic) coronary artery disease but cannot have procedures to open blocked arteries. It may help reduce future heart problems, while also checking for side effects and risks from aspirin.
KyotoAges 20 years+ - NCT05353946Recruiting
Rotational atherectomy elective vs emergency for heavily calcified blockages
This trial compares doing a special procedure (rotational atherectomy) before an emergency is needed versus using it as a rescue during a heart artery procedure. It is designed for people with very hard, calcified artery blockages and long-term kidney impairment, to see which approach works better and is safer.
MadridAges 18–100 - NCT05366153Recruiting
Plan to lower future heart attack risk after past cancer treatment
This trial tests whether a “risk-guided” care plan can help prevent coronary artery disease (the buildup that can lead to heart attacks) in people who had cancer treatment that can affect the heart. You may get closer heart risk monitoring and guidance to reduce risk factors, such as cholesterol—especially if you can safely take statins.
Hobart, TasmaniaAges 40–70 - NCT05367297Recruiting
Registry study of heart plaque in South Asian adults
This study tracks coronary plaque (fatty deposits in heart arteries) in South Asian adults and compares them with people of other backgrounds. You may be asked to have a special heart CT scan and basic measurements to help researchers understand differences in heart disease risk.
Dallas, TexasAges 18 years+ - NCT05380622Recruiting
CT scan to study plaque and blood flow in heart disease
This study uses a special heart CT scan (coronary CT angiography) to look at plaque and how blood flows in people with coronary artery disease. It may help match your scan results with heart measurements and guide future care decisions.
ShanghaiAges 18 years+ - NCT05416385Recruiting
Stress echo scan with special contrast to study carotid plaque
This study uses a heart stress ultrasound test, plus a contrast dye, to look for new blood vessel growth inside carotid plaque (the buildup in neck arteries). It may help doctors better judge the risk of stroke and determine which people need closer care.
Calgary, AlbertaAges 18 years+ - NCT05427786RecruitingPhase 4
Nicotinamide-like heart medicine given during stent helps blood flow
This trial studies whether a medicine (nicorandil) given into a coronary artery during stent procedures can help keep blood flow from getting worse. It may help people having stent placement for coronary artery disease by improving how well blood moves through the treated area.
SeoulAges 19 years+ - NCT05437900RecruitingPhase 4
A heart test to guide stent placement using blood-flow measurements
This Phase 4 study tests a way to measure blood flow in heart arteries to help doctors choose the best stent plan. It may help improve safety and effectiveness for people having elective heart stent procedures for stable angina or certain heart attacks.
Aalst, Oost-VlaanderenAges 18–85 - NCT05437965Recruiting
Registry study for repeat coronary blockages after stents
This study follows adults who have fast, unexplained re-narrowing of a coronary stent, to better understand what causes it and how to monitor it. You may help by allowing the study team to collect medical information over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05509010Recruiting
AI registry using CT scan to assess coronary artery disease
This trial builds and tests an AI system using information from a heart CT scan to help evaluate coronary artery disease (clogged heart arteries). If you need a CT coronary angiography for medical reasons, this may help improve how such scans are analyzed and used in care.
SingaporeAges 21–80 - NCT05532631Recruiting
Compare stent procedure versus bypass surgery for weak heart
This study compares two ways to improve blood flow to the heart—using stents through a catheter or bypass surgery—in people with heart muscle weakness and blockages in more than one coronary artery. It may help identify which approach leads to better outcomes over at least two years.
Créteil, Val De MarneAges 18 years+ - NCT05544864Recruiting
Stent or balloon treatment guided by heart scar pattern
This study looks at how to treat blocked heart arteries that have narrowed again after a prior drug-eluting stent. It compares using another drug-eluting stent versus a drug-coated balloon, chosen based on an imaging scan inside the artery (OCT), to reduce repeat narrowing.
Frankfurt am Main, HesseAges 18 years+ - NCT05549752RecruitingPhase 3
Flecainide vs amiodarone to treat fast heart rhythm in ER
This trial compares two medicines—flecainide and amiodarone—to help restore normal rhythm during an emergency visit for paroxysmal atrial fibrillation (a-fib). It’s aimed at people who also have coronary artery disease but no ongoing (residual) heart ischemia, and who have enough heart pumping strength.
AthensAges 18–85 - NCT05617599Recruiting
Checks safety of a stent used in complex heart artery disease
This study looks at how safe and effective a specific stent (SUPRAFLEX CRUZ) is when used in real-world care for people with heart artery blockages in more than one artery. Some participants will also be selected if their heart pumping strength is reduced.
Elche, AlicanteAges 18 years+ - NCT05624905Recruiting
Heart procedure registry for people getting angiography and stents
This study is a real-world registry that collects information from people who have a heart artery test (coronary angiography) and may also get a stent procedure (percutaneous coronary intervention). It may help doctors improve how these procedures are done by tracking outcomes and care.
SeoulAges 19 years+ - NCT05635227Recruiting
Medications during heart surgery to help control breathing and circulation
This study looks at whether giving dexamethasone and olanzapine during certain heart surgeries can improve how blood flow and ventilation (breathing support) are managed. It’s meant to see if these medicines help the body handle heart-lung bypass more safely.
CopenhagenAges 18 years+
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 733 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.