Clinical trials
Coronary Microvascular Disease clinical trials
Below are recruiting coronary microvascular disease clinical trials, each written for real people, not researchers. We’re tracking 59 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07222683Recruiting
How kidney transplant affects heart blood vessel health
This study looks at how receiving a kidney transplant changes the health of small blood vessels in the heart. It may help people with advanced kidney disease understand the benefits of transplant on their heart health.
Boston, MassachusettsAges 18 years+ - NCT02180178Recruiting
Heart catheter registry for slow coronary blood flow
This study builds a database of people who are having a coronary angiography (a heart blood-vessel X-ray test). It aims to better understand conditions like slow blood flow in the heart’s small vessels and may help improve how these conditions are diagnosed and treated.
MainzAges Any age - NCT07613996Recruiting
Blood Flow Measurement During Heart Imaging
This study examines how a special measurement technique works when blood vessels are dilated during a heart imaging procedure. It may help doctors better assess whether narrowing in your heart arteries needs treatment.
Shanghai, Please SelectAges 18 years+ - NCT06898541Enrolling by invitation
A device to treat chest pain from small heart artery disease
This trial tests a device called the Coronary Sinus Reducer for people with chest pain caused by problems in the small arteries of the heart. The device is placed in a vein near the heart to improve blood flow and reduce symptoms.
RotterdamAges 40 years+ - NCT05913999Enrolling by invitation
PET and heart scans during early chemotherapy
This trial studies how a specialized heart imaging test (PET/MPI) changes during the start of chemotherapy for cancer patients. It may help researchers understand whether this monitoring approach detects heart strain early and keeps patients safer during treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT05272618Recruiting
Testing heart vessel dysfunction after a heart attack
This trial looks at how to assess small blood-vessel (microvascular) problems in people who had a heart attack but whose main heart arteries are not blocked. It may help doctors better find what’s driving symptoms and choose the right tests and treatments.
Gwangju, GwangjuAges 19 years+ - NCT06529848Recruiting
Exercise for heart symptoms with clear arteries
This trial tests if exercise training can help people who have chest pain or shortness of breath even though their main heart arteries are not blocked. It focuses on those with small vessel disease in the heart, also known as INOCA.
CopenhagenAges 50 years+ - NCT05634031Recruiting
Study of heart vessel dysfunction seen on heart imaging
This study looks at coronary microvascular dysfunction (small blood vessel problems in the heart) using heart imaging. It may help researchers understand causes of chest tightness with activity and shortness of breath when the main heart arteries are not blocked.
New York, New YorkAges 18 years+ - NCT04440761Recruiting
Registry for people with MINOCA heart-related chest pain
This is a research registry that collects information from people diagnosed with MINOCA (a specific type of heart-related injury). It may help researchers better understand causes and outcomes for this condition.
LondonAges 16 years+ - NCT05743140Recruiting
Eye scan to help identify heart artery disease
This trial tests whether a special eye imaging scan (fundus OCTA) can help identify “CMD,” a type of heart-related blood flow problem. You may be eligible if you already had coronary angiography and your coronary narrowing is less than 50%.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06843902RecruitingPhase 2
Improving heart blood flow in women with HIV
This study is testing a medication that may help improve blood flow to the heart in women with HIV who also have diabetes, kidney disease, or protein in their urine. You would need to have a heart scan that shows low blood flow and not be taking certain diabetes drugs.
Boston, MassachusettsAges 45–75 - NCT04612322Recruiting
Study registry for microvascular angina patients
This registry study collects information from adults with microvascular angina (chest pain from small blood vessels in the heart). It may help researchers better understand how to assess and manage this condition over time.
Mainz, RLPAges 18–85 - NCT06089577RecruitingPhase 4
Cangrelor for heart blood flow during planned stent procedure
This trial tests if cangrelor, a fast-acting blood thinner, can prevent small vessel damage during a planned stent placement in patients with stable chest pain. It may help improve blood flow to the heart muscle.
FerraraAges 18 years+ - NCT06864234RecruitingPhase 4
Beta-blockers for chest pain without blocked arteries
This trial tests if beta-blocker medication improves blood flow and reduces resistance in the tiny blood vessels of the heart in people who have chest pain but no major blockages in their arteries.
Aalst, FlandersAges 18 years+ - NCT07498231Recruiting
Small heart vessel study for chest pain
This study looks at the tiny blood vessels in your heart (the microcirculation) that can cause chest pain even when the main arteries are open. It aims to better understand and treat this type of chest pain, called chronic coronary syndrome.
BialystokAges 18–75 - NCT06376630Recruiting
Esmolol for heart protection during heart attack
This study tests if giving a fast-acting heart medication (esmolol) early through an IV can protect the heart muscle during a heart attack. It may help patients who cannot receive a standard treatment due to certain risks.
MoscowAges 18 years+ - NCT07772570Recruiting
Studying blood markers in coronary artery disease
This study collects blood samples and images from patients with heart muscle damage or those undergoing coronary angiography. The goal is to find new biomarkers that could improve diagnosis and treatment of coronary artery disease.
OxfordAges 18–90 - NCT06588244Recruiting
Registry for chest pain with open arteries
This study is looking at people who have chest pain or shortness of breath but whose heart arteries look fairly open on an angiogram. It aims to understand why they have symptoms and how to improve care. You may qualify if you're having a coronary angiogram and it shows no major blockages.
Naples, ItalyAges Any age - NCT05762952RecruitingPhase 1
Dapagliflozin study for heart micro-blood-flow symptoms in women
This early-phase study tests whether dapagliflozin can improve tiny blood-vessel function in women who have heart-ache-like symptoms but no major blockage on heart scans. If it works, it may help symptoms related to “microvascular” heart circulation problems.
Charlottesville, VirginiaAges 18–99 - NCT05426408Recruiting
Test study for heart attacks without blocked arteries
This study looks at people who may have MINOCA (heart attack symptoms with no major artery blockage) or takotsubo syndrome (a temporary stress-related heart condition). The goal is to better understand these causes and how they should be diagnosed and treated.
StockholmAges 35–79 - NCT07293338Recruiting
Heart muscle blood flow study for dilated cardiomyopathy
This study looks at how small blood vessels in the heart affect outcomes in people with dilated cardiomyopathy (an enlarged, weak heart). You may qualify if you have heart failure with a weak pump and no significant blockages in your main heart arteries.
Hangzhou, ZhejiangAges 18 years+ - NCT07380919RecruitingPhase 2/Phase 3
Study of ranolazine to prevent heart muscle damage after a heart attack
This trial tests whether a medication called ranolazine can help prevent damage to tiny blood vessels in the heart after a certain type of heart attack (STEMI). You may be eligible if you recently had this kind of heart attack and had a successful procedure to open a blocked artery, but still have other blockages that can be treated with stents.
Catanzaro, ItalyAges 18–80 - NCT06969547Recruiting
Heart muscle coordination and microvessel function SPECT study
This study uses a special heart scan (SPECT) to look at how well the heart muscle is squeezing and how well the tiny blood vessels in the heart are working. It may help doctors understand why some people have chest pain even when their main arteries are not blocked.
TomskAges 18–75 - NCT04375306Recruiting
Testing a heart-pressure ratio to choose bypass surgery plan
This trial studies whether a special heart “pressure/flow ratio” test (measured during the procedure) can help doctors choose the best plan for coronary bypass surgery. It may improve how bypass targets the problem blood vessels, but only if certain heart and health factors fit the study rules.
BonheidenAges 18 years+
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Common questions
- Are there clinical trials for coronary microvascular disease?
- Yes. Clin2 currently lists 59 recruiting coronary microvascular disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary microvascular disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary microvascular disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.