Clinical trials
Critical Illness clinical trials
Below are recruiting critical illness clinical trials, each written for real people, not researchers. We’re tracking 336 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06574672Recruiting
Palliative care in the medical ICU
This study tests whether adding palliative care (comfort and support care) to usual MICU treatment helps patients and families. It takes place in the medical intensive care unit.
St Louis, MissouriAges 18 years+ - NCT06411561Recruiting
Boosting memory after ICU stay for older adults
This study tests a combination of activities (like cognitive training and exercise) to help older adults recover thinking and memory after a serious illness in the ICU. It may help you regain sharpness and independence after leaving the intensive care unit.
Seattle, WashingtonAges 60 years+ - NCT06714240Recruiting
Extra protein to support muscle strength in ICU
This study tests whether giving extra protein through a feeding tube can help ICU patients maintain muscle strength. It may be an option for people who are expected to stay in the ICU for at least a week and need a breathing machine.
Hasselt, LimburgAges 18 years+ - NCT05865314Recruiting
Nutrition plus early therapy for adults in long ICU stays
This trial studies whether a planned nutrition plan, along with early physiotherapy (physical therapy), can improve outcomes for adults who expect to stay in the ICU for at least 7 days. It includes people who need feeding through a tube and/or special IV nutrition while on a breathing machine.
Geneva, Canton of GenevaAges 18 years+ - NCT06692400Recruiting
Suctioning, pain, and blood markers in intubated patients
This study looks at how routine suctioning of the breathing tube affects pain levels and certain substances in the blood in adults who are on a breathing machine for serious infections like flu, pneumonia, COVID, or sepsis. It may help doctors better understand and manage your comfort during this procedure.
Loma Linda, CaliforniaAges 18 years+ - NCT06677502Enrolling by invitation
Cerebrolysin for delirium in ICU patients
This trial tests a medicine called Cerebrolysin to see if it helps reduce confusion and agitation (delirium) in patients who are critically ill and being treated in the ICU. It may be an option for you if you are over 18 and have delirium symptoms.
Lubin, Lublin VoivodeshipAges 18–100 - NCT06669494Enrolling by invitation
Study on ICU muscle weakness detection and monitoring
This study aims to find better ways to detect and track muscle weakness that can happen during an ICU stay. If you or your loved one is in the ICU, this research could help improve early diagnosis and care.
Seoul, SeoulAges 18 years+ - NCT06667999RecruitingPhase 4
Intensive care platform trial for adult ICU patients
This major trial tests multiple treatments at once for adults admitted to the ICU. If you are an ICU patient, you may be able to join and receive one of several possible treatments aimed at improving recovery.
ViennaAges 18 years+ - NCT06652126Recruiting
Immune status and ICU infections study
This study looks at how having a weakened immune system affects the risk of getting infections with hard-to-treat bacteria in the ICU. Depending on your immune status, you may be placed in a group that helps doctors understand who is most at risk.
LilleAges 18 years+ - NCT06606119Recruiting
Brain, bone marrow, and gut study after major injury
This study is looking at how the brain, bone marrow, and gut interact after a severe injury. It may help doctors understand how to better treat trauma patients.
Gainesville, FloridaAges 18–100 - NCT05985525Recruiting
Monitoring blood flow in ICU patients with severe infection or shock
This study monitors tiny blood vessels under the tongue using a non-invasive device to see how well blood flows in ICU patients on a breathing machine. Researchers hope to improve care for patients with serious infections or shock.
Winnipeg, ManitobaAges 18 years+ - NCT06588556Recruiting
Improving Care for Older Adults in the ICU
This study tests a program to improve communication and support for older adults in the ICU and their families. It may help families feel more supported during a serious illness.
Birmingham, AlabamaAges 18 years+ - NCT06575530RecruitingPhase 4
Remimazolam for sedation after non-cardiac surgery
This trial tests a sedative called remimazolam besylate in patients who need a breathing tube and light sedation after non-cardiac surgery. The goal is to see if it works well and is safe.
Beijing, Beijing MunicipalityAges 18–64 - NCT02182180Recruiting
SC2i tissue and data collection for people needing urgent care
This study collects small samples of tissue and body fluids and related health data from people who need surgery or treatment in an emergency or critical care setting. The goal is to build a resource researchers can use to better understand illness and improve care.
Atlanta, GeorgiaAges 18 years+ - NCT06526533RecruitingPhase 3
Red blood cell transfusion thresholds for ECMO patients
This trial is testing whether a higher or lower threshold for red blood cell transfusions is better for people on ECMO (a heart-lung machine). It aims to find the safest way to manage transfusions during ECMO treatment.
Camperdown, New South WalesAges Any age - NCT06521086Recruiting
Better nutrition recovery for trauma patients
This study tests if a special nutrition plan helps older adults recover better after a traumatic injury. It aims to improve healing by providing extra nutrition through food and drinks.
Durham, North CarolinaAges 45 years+ - NCT06505447Recruiting
Sleep study for kids in the PICU
This study looks at how sleep and body rhythms are affected when a child is in the pediatric intensive care unit (PICU). It may help doctors find ways to improve sleep for children who are in the hospital.
Buffalo, New YorkAges 3–6 - NCT06481644Recruiting
Study of kids in Asian pediatric ICUs
This study looks at children admitted to pediatric intensive care units (ICUs) in Asia to understand their health patterns and outcomes. It may help improve care for future patients.
SingaporeAges Any age - NCT06478160Recruiting
Closed blood-sampling system for ICU patients
This trial is testing a new way to draw blood from an arterial line that may reduce infection and blood loss. It is for adults in the ICU who need an arterial line for several days.
Madrid, MadridAges 18 years+ - NCT06486467Recruiting
AI-guided ultrasound to measure blood flow in ICU patients
This trial tests whether a simple ultrasound measurement of blood flow in your heart, guided by artificial intelligence, can be reliably done by minimally trained staff. It aims to help doctors decide when to give fluids to ICU patients who need them.
LimogesAges 18 years+ - NCT06259565RecruitingPhase 3
Breathing mask sedation trial for agitated adults
This trial tests whether adding a sedative called dexmedetomidine to non-invasive ventilation (a breathing mask) helps adults who are agitated or uncomfortable while on the mask. It aims to improve comfort and avoid the need for a breathing tube.
Surrey, British ColumbiaAges 18 years+ - NCT05146336Recruiting
CytoSorb registry for critically ill patients needing blood treatment
This registry collects information about critically ill patients who receive the CytoSorb 300 mL blood treatment. It may help doctors better understand when the treatment works best and when it should not be used.
KlagenfurtAges Any age - NCT06446739Recruiting
Low-dose vs standard-dose kidney therapy for ICU patients
This study compares two different doses of continuous kidney replacement therapy (CRRT, a type of dialysis) for patients in the intensive care unit with acute kidney injury. It aims to find out if a lower dose is as safe and effective as the standard dose.
Rochester, MinnesotaAges 18 years+ - NCT05740735Recruiting
Testing sound-based brain signals to predict recovery after severe brain injury
This study checks how a brain responds to two kinds of sounds—neutral tones and emotional sounds—in people with a persistent disorder of consciousness after a serious event like stroke, head injury, or cardiac arrest. The goal is to see whether these brain “signal” tests can help doctors predict outcomes.
Paris, IDFAges 18 years+
Hear when a new Critical Illness trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for critical illness?
- Yes. Clin2 currently lists 336 recruiting critical illness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical illness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical illness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.