Clinical trials
Critical Illness clinical trials
Below are recruiting critical illness clinical trials, each written for real people, not researchers. We’re tracking 336 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07035951Recruiting
Family involvement for very old ICU patients
This study looks at how family members can be involved in making treatment decisions for older patients (75+) in the ICU. It aims to improve care for very old patients who are expected to stay in the ICU for more than 3 days.
LondonAges 75 years+ - NCT07035106Recruiting
Using wearables to track recovery after ICU
This study tests if a wearable device and health summaries can help people recover after a stay in the intensive care unit (ICU). It is for people who have diabetes or heart problems and left the ICU within the last 2 years.
ViennaAges 18–65 - NCT07034599Recruiting
Negative pressure breathing after heart pump implant
This study looks at how a breathing machine that uses negative pressure (like a vacuum) affects the heart and blood flow in people who have a left ventricular assist device (LVAD), a type of heart pump. It may help doctors learn the best way to support breathing after surgery.
KarlsburgAges 18 years+ - NCT07026656Recruiting
Quick diagnosis of ventilator pneumonia in critically ill children
This study tests a new way to quickly diagnose pneumonia in children on breathing machines in the ICU. It uses information from the body and germs to find the right treatment faster.
CambridgeAges 1 month–16 years - NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients
This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.
London, LondonAges 18–100 - NCT07027813Recruiting
Ambulance video care for children
This trial tests whether using a tablet computer and video connection in an ambulance helps doctors and emergency workers care for children during the ride to the hospital. It aims to see if this approach is practical and improves treatment.
Karachi, SindhAges 1 minute–14 years - NCT07017517Recruiting
Exercise therapy for weakness after sepsis in the ICU
This trial tests whether adding physical therapy early in the ICU can help people with sepsis regain strength and reduce muscle weakness. It focuses on patients who need a breathing tube for at least a week and have a high level of organ failure.
Santiago, Metropolitan RegionAges 18 years+ - NCT06999161Recruiting
Tracking Antibiotic Levels in ICU Brain Injury Patients
This study monitors the amount of certain antibiotics in the blood of patients with acute brain injury in the intensive care unit. It aims to make sure the antibiotics are at the right level to fight infection, especially in patients whose kidneys are clearing drugs faster than normal.
NîmesAges 18 years+ - NCT07013175Recruiting
Wise Choices in the Intensive Care Unit
This study looks at how decisions are made in the ICU. It may help improve care for adult patients in Swedish intensive care units.
StockholmAges 18 years+ - NCT06174610Recruiting
Kidney ultrasound for ICU patients on dialysis
This study looks at how kidney ultrasound can help monitor critically ill patients who need continuous dialysis for acute kidney injury. The results may help doctors better manage treatment.
Opole, Opole VoivodeshipAges 18 years+ - NCT06997822Recruiting
Recovery program for ICU survivors
This trial tests a program to help people who were on a breathing machine in the ICU recover after leaving the hospital. It uses a smartphone app to guide your recovery at home.
TaipeiAges 18 years+ - NCT07000526RecruitingPhase 4
Inhaled sedation for critically ill patients on breathing machines
This trial compares inhaled isoflurane sedation to standard propofol sedation in deeply sedated patients on ventilators. It aims to see if inhaled sedation improves outcomes.
Orihuela, AlicanteAges 18–80 - NCT06867354Recruiting
Breathing difficulty in obese patients during weaning from ventilator
This study looks at how often obese patients have trouble breathing when doctors try to remove the breathing tube (weaning) in the ICU. The goal is to understand what causes this and how it affects recovery.
Paris, ParisAges 18 years+ - NCT06977555Enrolling by invitation
Talking with ICU patients on a breathing machine
This study looks at how nurses and doctors communicate with patients who are awake but on a breathing machine (ventilator) in the intensive care unit (ICU). The goal is to improve communication and make the experience better for patients.
OsloAges 18 years+ - NCT06039501Recruiting
The Family Perspectives Project Pilot Trial
This study looks at how to improve communication between families and the care team when a loved one is on a breathing machine in the intensive care unit. It may help families feel more supported and involved in care decisions.
Los Angeles, CaliforniaAges 18 years+ - NCT06934876Recruiting
Comparing two CO2 detectors during breathing tube placement in critically ill adults
This study compares two ways of checking that a breathing tube is placed correctly in seriously ill adults: one uses a device that shows a waveform on a screen, and the other uses a color-changing test. It may help doctors choose the best method for patients in the emergency room or ICU.
Chicago, IllinoisAges 18 years+ - NCT06929702RecruitingPhase 4
Precision dosing of antibiotics for critically ill children
This trial tests a personalized dosing approach for certain antibiotics (amoxicillin-clavulanic acid, piperacillin-tazobactam, and meropenem) in hospitalized children with serious infections. The goal is to adjust the dose based on blood tests to make sure each child gets the right amount of medicine.
GhentAges birth–18 years - NCT05780099Recruiting
Study of patients treated in internal medicine clinics
This observational study follows people receiving care in Internal Medicine at San Raffaele Hospital to better understand what kinds of conditions they have. It does not test a new treatment, but your information may help improve future care.
MilanAges 18 years+ - NCT06904001Enrolling by invitation
Early warning model for sepsis in critically ill patients
This trial is building a tool to predict sepsis, a life-threatening response to infection, in intensive care patients. It may help doctors act faster to prevent complications.
Wenzhou, ZhejiangAges 18–99 - NCT06843668RecruitingPhase 2/Phase 3
Best ways to give colistin for tough infections in the ICU
This study tests different ways of giving the antibiotic colistin to patients in the ICU with infections that are hard to treat. The goal is to find the best dosing schedule to help you fight the infection more effectively.
BuraidahAges 18 years+ - NCT06840756RecruitingPhase 4
Does donor-patient sex matching improve blood transfusion outcomes?
This trial tests whether giving ICU patients blood from a donor of the same sex (male-to-male or female-to-female) leads to better recovery compared to mismatched transfusions. The goal is to see if matching donor and patient sex makes a difference in how well patients do.
Hamilton, OntarioAges 18 years+ - NCT06835491RecruitingPhase 3
Amiodarone to prevent heart rhythm problems after cardiac arrest
This trial tests whether giving the drug amiodarone early can prevent dangerous heart rhythm problems in patients who survived a cardiac arrest with a shockable rhythm. If it works, it could help more people recover.
AmiensAges 18 years+ - NCT06822465Recruiting
Gut bacteria study in critically ill patients
This study looks at the bacteria in the gut of people who are very ill in the hospital. It may help doctors understand how gut health affects recovery.
Hyde Park, IllinoisAges 18–85 - NCT04588311RecruitingPhase 3
Epoetin to improve outcomes in severe trauma ICU patients
This trial tests epoetin alfa (a blood-building medicine) to help reduce death and severe disability in critically ill trauma patients in the ICU. You may be considered if your ICU team expects a longer stay and the timing after injury is early.
Camperdown, New South WalesAges 18–75
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Common questions
- Are there clinical trials for critical illness?
- Yes. Clin2 currently lists 336 recruiting critical illness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical illness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical illness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.