Clinical trials
Critical Illness clinical trials
Below are recruiting critical illness clinical trials, each written for real people, not researchers. We’re tracking 352 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07369258Recruiting
Music to prevent confusion in the ICU for older adults
This trial tests whether listening to music can help prevent delirium (sudden confusion) in older patients in the intensive care unit. If it works, it could offer a simple, drug-free way to protect your thinking during a hospital stay.
Buenos Aires, Buenos Aires F.D.Ages 65 years+ - NCT07372794Recruiting
Lung imaging-guided breathing therapy for patients on ventilators for weeks
This study tests whether using a special lung imaging technique called EIT can help guide breathing exercises and physical therapy for people who have been on a breathing machine for 21 days or more. The goal is to see if this approach helps your lungs work better and speeds up recovery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07377162Recruiting
Hyperoxia effects on brain blood flow in ICU patients
This trial studies how giving extra oxygen (hyperoxia) affects blood flow in the brain for patients on a breathing machine in the intensive care unit. The goal is to see if short bursts of higher oxygen levels are safe and how they change brain activity.
BrusselsAges 18 years+ - NCT07384585Recruiting
Light therapy study for children in the ICU
This study tests whether light therapy can help children in the pediatric intensive care unit (ICU) feel better and recover. A parent or guardian must be at the bedside and speak English.
Columbus, OhioAges 4–17 - NCT01068990Recruiting
Testing how to identify pneumonia germs in ICU patients
This study looks at how well doctors can detect and identify the cause of new pneumonia in people in the medical intensive care unit (ICU). It may help improve how pneumonia is diagnosed and treated in critically ill patients.
SeoulAges 16 years+ - NCT02299921Recruiting
Alcohol and drug effects on immunity in ICU breathing patients
This study looks at how alcohol and other drugs can affect the body’s immune system in people who are very sick in the ICU due to breathing problems. It may help doctors better understand immune changes during critical illness and respiratory failure.
Aurora, ColoradoAges 18–90 - NCT02182180Recruiting
SC2i tissue and data collection for people needing urgent care
This study collects small samples of tissue and body fluids and related health data from people who need surgery or treatment in an emergency or critical care setting. The goal is to build a resource researchers can use to better understand illness and improve care.
Atlanta, GeorgiaAges 18 years+ - NCT02893462Recruiting
Collecting health and signal data from ICU patients
This trial sets up a way to collect and store physiological readings (like vital-sign data) from adults in the intensive care unit. It aims to improve how doctors understand and monitor critically ill patients over time.
BrestAges 18 years+ - NCT07417969Recruiting
Albumin with furosemide for fluid overload in ICU
This study tests whether giving a medicine called albumin together with a water pill (furosemide) helps ICU patients who have too much fluid in their body and are making very little urine. The goal is to see if this combination can improve urine output and protect kidney function.
Querétaro City, QuerétaroAges 18–100 - NCT07418242Recruiting
New markers for kidney risk after heart surgery
This study looks at whether certain blood or urine markers can predict kidney problems in people having high-risk heart surgery. The goal is to find early warning signs so doctors can take steps to protect your kidneys.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT07447791Recruiting
Comparing low vs standard dialysis in ICU patients
This trial compares a lower dose versus a standard dose of continuous kidney replacement therapy (CRRT) for critically ill patients with acute kidney injury (AKI — sudden kidney failure). It aims to see if lower doses are safe and effective.
London, Greater LondonAges 18 years+ - NCT07448805Recruiting
Accuracy and safety of a glucose monitor in the ICU
This trial tests a continuous glucose monitoring system (Syai Tag) in the intensive care unit (ICU). It aims to see how well it measures blood sugar levels safely compared to standard methods.
MariborAges 18 years+ - NCT07460141Recruiting
Blood tests to predict death risk after surgery in the ICU
This study is looking at whether certain blood tests can help predict the risk of death after surgery in ICU patients. If you have had surgery and are now in the ICU, your blood samples may help doctors learn more.
TrabzonAges 18 years+ - NCT07478380Recruiting
Skin oxygen monitoring in pediatric ICU
This study checks if a skin sensor can accurately measure oxygen levels in the blood of children in the intensive care unit, compared to standard blood tests. It may help reduce the need for frequent needle sticks.
Istanbul, KadıkoyAges 1 month–18 years - NCT07000526RecruitingPhase 4
Inhaled sedation for critically ill patients on breathing machines
This trial compares inhaled isoflurane sedation to standard propofol sedation in deeply sedated patients on ventilators. It aims to see if inhaled sedation improves outcomes.
Orihuela, AlicanteAges 18–80 - NCT03419260Recruiting
Continuous EEG monitoring in critically ill children
This study looks at whether continuous brain-wave monitoring can guide seizure care in sick children in the pediatric intensive care unit. It also studies how this approach may affect children’s thinking and behavior later.
Philadelphia, PennsylvaniaAges 1 month–18 years - NCT07499401Recruiting
Fluid response test in ICU patients with vein congestion
This study looks at how tiny blood vessels respond to extra fluids in ICU patients who have vein congestion. It helps doctors understand if giving more fluid is helpful or harmful for you.
Ancona, ItalyAges 18 years+ - NCT07511582RecruitingPhase 2
Steroids for severe breathing problems in the ICU
This study tests whether a corticosteroid (a type of anti-inflammatory medicine) can help people with severe breathing problems or serious infections who have a specific 'hyperinflammatory' pattern. If you are in the ICU on a ventilator, this trial may be an option for you.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07514650Recruiting
Citrate Blood Thinner Safety in Critical Kidney Care
This study tests whether a specific blood-thinning method using citrate works safely and effectively in critically ill patients whose kidneys have suddenly stopped working and need a special filtering machine. Researchers want to confirm that this approach prevents dangerous blood clots while keeping patients safe.
Barcelona, BarcelonaAges 18 years+ - NCT07536750Recruiting
Comparing Two Sedation Drugs for ICU Patients on Breathing Support
This study compares two medications (ciprofol and propofol) used to keep ICU patients calm and comfortable while they receive non-invasive breathing support, such as oxygen masks or tubes that help them breathe without a breathing tube in their windpipe. Researchers want to see which drug works better and is safer.
Guangzhou, GuangdongAges 18 years+ - NCT07542366Recruiting
Testing a new lung imaging method in ICU patients
This study tests whether a special imaging technique called EIT (electrical impedance tomography) combined with a safe contrast injection can measure blood flow in the lungs of patients on breathing machines. If it works, it could help doctors better manage critically ill patients.
Wuhu, AnhuiAges 18 years+ - NCT07542613Recruiting
Educational Program for ICU Patients' Recovery
This study tests whether teaching ICU patients and their families about recovery can help patients regain strength and function after leaving the hospital. Researchers will follow patients for several months after discharge to see if the education makes a difference in their recovery.
Orihuela, AlicanteAges 18 years+ - NCT07551258Recruiting
Immune System Changes and Lung Infection in Critically Ill Older Adults
This study looks at how the immune system changes in older patients on breathing machines in the ICU, and whether these changes affect the risk of developing pneumonia. Understanding this may help doctors better protect critically ill patients from infection.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT07562048Recruiting
Comfort Cuddling for Children in Critical Care
This study looks at whether gentle cuddling and physical comfort help children feel better while they're in the intensive care unit. Researchers believe close contact with caregivers may reduce stress and improve how children recover.
Calgary, AlbertaAges Up to 18 years
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Common questions
- Are there clinical trials for critical illness?
- Yes. Clin2 currently lists 352 recruiting critical illness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical illness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical illness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.