Clinical trials
Critical Illness clinical trials
Below are recruiting critical illness clinical trials, each written for real people, not researchers. We’re tracking 352 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07034599Recruiting
Negative pressure breathing after heart pump implant
This study looks at how a breathing machine that uses negative pressure (like a vacuum) affects the heart and blood flow in people who have a left ventricular assist device (LVAD), a type of heart pump. It may help doctors learn the best way to support breathing after surgery.
KarlsburgAges 18 years+ - NCT07035106Recruiting
Using wearables to track recovery after ICU
This study tests if a wearable device and health summaries can help people recover after a stay in the intensive care unit (ICU). It is for people who have diabetes or heart problems and left the ICU within the last 2 years.
ViennaAges 18–65 - NCT07074028Recruiting
Tracking muscle changes in ICU patients with sepsis
This study is for people in the ICU with sepsis who need a breathing machine for a long time. It monitors muscle changes during recovery to understand how sepsis affects muscles.
Saint-BrieucAges 18 years+ - NCT07093203Recruiting
Rezafungin for fungal infection in the belly
This trial tests how well rezafungin, an antifungal medicine, spreads in belly fluid when given during surgery for a suspected fungal infection in the abdomen. It aims to see if it's a good treatment option for patients needing abdominal surgery.
Vandœuvre-lès-Nancy, LorraineAges 18 years+ - NCT07093437Recruiting
Comparing ways to secure urinary catheters in ICU patients
This study compares two methods of securing a urinary catheter to the thigh to see which works better. It's for patients in the intensive care unit (ICU) who need a catheter for more than 48 hours.
BarcelonaAges 18–99 - NCT07094425Recruiting
Heart function study for ICU patients on breathing machines
This study looks at how the heart is affected in critically ill patients who need a breathing machine. It uses ultrasound and other simple tests to check for heart problems that can happen in the ICU, which may help doctors find and treat them earlier.
Vienna, State of ViennaAges 18 years+ - NCT07124442Recruiting
Muscle function study for ICU patients
This study looks at muscle function and disease severity in people who have been in the intensive care unit (ICU) for at least 48 hours. It aims to understand how muscle problems relate to recovery and risk, without requiring a breathing machine.
Istanbul, EsenyurtAges 18 years+ - NCT07125079Recruiting
Studying immune cells and a new treatment for ARDS
This study looks at how the immune system responds in people with ARDS (a severe lung injury) and tests a new treatment called PIP-2 in the lab to see if it might help. It aims to better understand lung injury and find new ways to treat it.
Philadelphia, PennsylvaniaAges 21–90 - NCT07128446Recruiting
Goal setting with COPM in the PICU
This trial is testing a new way to set goals for children in the pediatric intensive care unit. Researchers want to see if a tool called COPM helps caregivers and therapists work together to choose the most important rehab goals.
Seoul, Gangnam-guAges 1–18 - NCT07130799Recruiting
Monitoring immune response in severe abdominal infections with fungal risk
This trial monitors a marker of immune function (monocyte HLA-DR) in patients with severe abdominal infections that may lead to fungal infections. It aims to see if this marker can help guide treatment.
Vandœuvre-lès-NancyAges 18 years+ - NCT07143695Recruiting
Chest muscle ultrasound to guide breathing machine weaning
This study uses an ultrasound to measure how well a chest muscle moves when you try to breathe on your own. It may help doctors decide if you are ready to come off the breathing machine.
Cairo, Giza GovernorateAges 18–65 - NCT07170527Recruiting
Metabolic signs, recovery, and physical function after ICU stay
This study looks at whether certain molecules in the blood (metabolic signatures) are linked to how well people recover physically after a serious illness requiring intensive care. By understanding these links, doctors might be able to better predict and support recovery.
Ede, GelderlandAges 18 years+ - NCT07191743Recruiting
Functional Assessment in ICU Patients
This study observes how well adults in the intensive care unit (ICU) can function in daily activities, like moving and caring for themselves. It aims to understand recovery and may help improve care for future ICU patients.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT07211620Recruiting
Using procalcitonin blood tests to guide antibiotic decisions in the ICU
This study compares two ways of using a blood test called procalcitonin to decide when to start antibiotics in critically ill patients with a new infection. The goal is to reduce unnecessary antibiotic use while still effectively treating infections.
BudapestAges 18 years+ - NCT07221370RecruitingPhase 2/Phase 3
Vancomycin to prevent C. diff infection in ICU patients
This trial tests whether giving vancomycin through a tube into the stomach can prevent a serious gut infection called C. diff in people who are very sick in the ICU and taking antibiotics. If you qualify, you might receive this medicine to lower your risk.
Moreno Valley, CaliforniaAges 18 years+ - NCT07225257Recruiting
Recovering Physical Function After ICU Stay in Older Adults
This study looks at how to help older adults regain physical strength after a serious illness that required time in the ICU. It aims to find the best ways to help you recover daily activities like walking and moving around.
Lexington, KentuckyAges 18–99 - NCT07249749Recruiting
Factors linked to death in the ICU
This study looks at factors that may be linked to death in the ICU. It is for adults who are currently in the intensive care unit.
Villavicencio, Meta DepartmentAges 18–100 - NCT07262320Recruiting
Kidney treatment in Latin American ICUs
This study looks at how dialysis (renal replacement therapy) is used for patients in intensive care units (ICUs) with severe acute kidney injury in Latin America. Your participation can help improve care for people with kidney problems.
CochabambaAges 18 years+ - NCT07298720Recruiting
Checking fluid needs with a light-based muscle test
This study uses a non-invasive light-based device on your arm muscle to see if you need more fluids. It aims to replace invasive monitoring for patients with arterial lines.
Sabadell, Spain/ BarcelonaAges 18 years+ - NCT07307508Recruiting
Scalp block for headache after aneurysm bleeding
This trial tests if a scalp nerve block can better manage severe headaches after a brain aneurysm rupture. It is for patients who had an aneurysm treated with coiling in the intensive care unit.
DohaAges 18 years+ - NCT07323472Recruiting
Body positioning and breathing in critically ill patients on ventilators
This study tests whether turning patients on their side affects their breathing and lung health. It aims to improve care for people who need a breathing machine.
Recife, PernamuAges 18 years+ - NCT07338240Recruiting
Testing a sickness scoring system in Turkish ICUs
This trial is studying how well a scoring system (SOFA-2) works in Turkish intensive care units (ICUs) to measure how sick patients are. It may help doctors better understand and treat people in ICUs in Türkiye.
Izmir, İzmirAges 18 years+ - NCT07364162RecruitingPhase 2
Ketone Drink for Confusion in the ICU
This trial tests if giving a special ketone drink through a feeding tube or by mouth can help clear confusion in ICU patients. It might speed up recovery and improve thinking.
Nashville, TennesseeAges 18 years+ - NCT07367113Recruiting
Finger sensor guided fluids for skin health in older ICU patients
This study tests if using a finger sensor to guide fluid therapy can prevent skin failure in older ICU patients with sepsis or shock. It compares usual care to personalized fluid management.
Nantong, JiangsuAges 65 years+
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Common questions
- Are there clinical trials for critical illness?
- Yes. Clin2 currently lists 352 recruiting critical illness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical illness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical illness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.