Clinical trials
Critically Ill Patients clinical trials
Below are recruiting critically ill patients clinical trials, each written for real people, not researchers. We’re tracking 317 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06189924Recruiting
Breath analysis in ventilated ICU patients
This study collects and analyzes the moisture you breathe out while on a ventilator in the ICU. It aims to learn more about your condition by examining your breath.
OlomoucAges 18 years+ - NCT06386796Recruiting
Using ultrasound to predict kidney trouble in high-risk patients
This study uses a simple ultrasound test (kidney artery scan) to see if it can predict kidney problems early in people who are very ill. It may help doctors protect your kidneys during your hospital stay.
Aswān, Aswan GovernorateAges 18–80 - NCT06460363Recruiting
Electrical brain stimulation for delirium in ICU patients
This trial tests whether a gentle electrical current applied to the scalp can help treat delirium (sudden confusion) in intensive care patients. It aims to improve recovery in people who have had confusion for more than 24 hours.
KuopioAges 18 years+ - NCT06702813Recruiting
High-frequency vibration breathing treatment for ICU patients
This trial tests a device called MetaNeb that delivers high-frequency vibrations to help clear mucus and open collapsed air sacs in the lungs. It is designed for patients in the ICU who are awake, alert, and have trouble breathing or need extra oxygen.
Shanghai, Shanghai MunicipalityAges 1.5 years–80 years - NCT07448805Recruiting
Accuracy and safety of a glucose monitor in the ICU
This trial tests a continuous glucose monitoring system (Syai Tag) in the intensive care unit (ICU). It aims to see how well it measures blood sugar levels safely compared to standard methods.
MariborAges 18 years+ - NCT06749483Recruiting
Gut bacteria and infection in intensive care patients
This study looks at how gut bacteria affect severe infections in the ICU. It tests whether the microbiome can be a source of sepsis and a target for treatment. If you are critically ill or a long-term sepsis survivor, you might help find new ways to prevent infections.
Jena, ThuringiaAges 18 years+ - NCT05537298Recruiting
Help for muscle recovery after serious ICU illness
This trial looks at how to improve muscle strength and function after a stay in the ICU for sepsis or acute respiratory failure. If you recover from the illness but your muscles become weak, this study may test an approach to help rebuild strength faster.
Birmingham, AlabamaAges 18 years+ - NCT06697470Recruiting
Ultrasound and fluid monitoring in the ICU
This study uses ultrasound and electrical impedance (skin electrodes) to track fluid balance in the muscles and tissues of ICU patients. It aims to see if these tools can help doctors better manage fluids during your stay.
Boussu, HainautAges 18 years+ - NCT04875260Recruiting
Carefully compare outcomes in ICU patients
This study focuses on critically ill people in the intensive care unit (ICU). It aims to learn what affects outcomes and resources, which may help improve how care is planned for ICU patients.
DouliuAges 20 years+ - NCT07109570Recruiting
Checking breathing effort in ICU patients on a ventilator
This trial measures how your breathing muscles work while we try taking you off the breathing machine. The results could help doctors predict when you're ready to breathe on your own.
LeidenAges 18 years+ - NCT06285162Recruiting
Nerve health monitor during ICU dialysis
This trial uses a special monitor (called ANI) to check how well your nervous system is working while you are on continuous kidney dialysis in the ICU. It may help doctors better understand your body's response to fluid removal.
BronAges 18 years+ - NCT04043598Recruiting
Fluids choice after brain bleed to improve brain outcomes
This trial studies whether giving a specific type of IV fluid (a salt-water fluid in the vein) after a type of brain bleed can improve neurological recovery. It focuses on adults with a non-traumatic subarachnoid hemorrhage (a bleeding in the space around the brain) given soon after diagnosis.
Sankt Gallen, Canton of St. GallenAges 16 years+ - NCT06362525Recruiting
Episodes of Disconnected Consciousness in Emergency Patients
This study looks at brief episodes of being disconnected from your surroundings among very ill emergency patients. Researchers want to see how often this happens and what it means for recovery.
LiègeAges 18 years+ - NCT06961227Recruiting
Comparing two breathing machine settings in the ICU
This trial compares two different ways a breathing machine can help you breathe. It uses a special imaging technique to see which method works better for patients in the intensive care unit.
SanliurfaAges 18 years+ - NCT06391424Recruiting
Oxygen use and breathing effort during ventilator weaning
If you are on a breathing machine in the ICU and ready to try breathing on your own, this study looks at how much oxygen your body uses during that test. It may help doctors better understand when you are ready to come off the ventilator.
Leiden, South HollandAges 18 years+ - NCT06521086Recruiting
Better nutrition recovery for trauma patients
This study tests if a special nutrition plan helps older adults recover better after a traumatic injury. It aims to improve healing by providing extra nutrition through food and drinks.
Durham, North CarolinaAges 45 years+ - NCT07418242Recruiting
New markers for kidney risk after heart surgery
This study looks at whether certain blood or urine markers can predict kidney problems in people having high-risk heart surgery. The goal is to find early warning signs so doctors can take steps to protect your kidneys.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT04850456Recruiting
Gamma globulin treatment for critically ill children with inflammation surge
This trial studies whether giving “human gamma globulin” can improve outcomes in very sick children in the ICU who have a severe infection causing an extreme inflammation reaction (“inflammatory storm”). If you’re in the hospital ICU with this complication, the study may offer a targeted treatment strategy and careful monitoring.
Shanghai, Shanghai MunicipalityAges 4 weeks–18 years - NCT06482892RecruitingPhase 2
Testing a new drug for severe leg artery disease
This trial tests an experimental drug for people with critical limb ischemia, a serious condition where not enough blood reaches the legs. It aims to see if the drug can help with pain or healing of leg ulcers without the need for surgery.
Suzhou, JiangsuAges 18 years+ - NCT07536750Recruiting
Comparing Two Sedation Drugs for ICU Patients on Breathing Support
This study compares two medications (ciprofol and propofol) used to keep ICU patients calm and comfortable while they receive non-invasive breathing support, such as oxygen masks or tubes that help them breathe without a breathing tube in their windpipe. Researchers want to see which drug works better and is safer.
Guangzhou, GuangdongAges 18 years+ - NCT02766166Recruiting
Study of health status scores in monitored hospital patients
This study looks at how a “health score” measures a patient’s condition and outcomes while they are in the hospital with heart monitoring. It may help doctors better assess risk and track how patients do over time.
Indianapolis, IndianaAges 18 years+ - NCT07740304Recruiting
Blood flow test to predict survival in sepsis patients
This study checks if a simple blood flow measurement can help predict which patients with sepsis are at higher risk of dying within 28 days. The goal is to see if this test can guide treatment decisions in the ICU.
Edirne, MerkezAges 18 years+ - NCT04722939Recruiting
Testing brain function outcomes after ICU kidney failure treatment
This trial studies how treating severe kidney injury in the ICU may affect patients’ brain and thinking function over time. It compares measurements of brain activity and function after starting kidney replacement therapy.
Kingston, OntarioAges 18 years+ - NCT05551325Recruiting
Resetting sleep timing for ICU patients to support recovery
This study tests a “sleep chronobundle,” a set of sleep and light-timing steps, to improve daily sleep-wake timing in people in the ICU on breathing or blood-pressure support. It also checks whether the body’s sleep rhythms are more aligned during critical illness and over time.
New Haven, ConnecticutAges 18 years+
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Common questions
- Are there clinical trials for critically ill patients?
- Yes. Clin2 currently lists 317 recruiting critically ill patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critically ill patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critically ill patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.