Clinical trials
Depressed clinical trials
Below are recruiting depressed clinical trials, each written for real people, not researchers. We’re tracking 1,504 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07655232Recruiting
Behavioral program for depression in nursing homes
This study tests a behavioral program designed to help skilled nursing facility residents with depression. The program aims to improve mood and quality of life.
Boston, MassachusettsAges 18 years+ - NCT06017622Recruiting
THC Levels in Young People with Cannabis Overdose in the ER
This study looks at the amount of THC (the active ingredient in cannabis) in the blood of children and teens who come to the emergency room with severe drowsiness or confusion after using cannabis. It will help doctors better understand how cannabis affects young people.
Worcester, MassachusettsAges Any age - NCT07422909Enrolling by invitation
Bridging the gap: adding exercise to depression treatment for teens
This trial tests if adding physical activity to standard depression care helps teens feel better. It's for teens ages 12 to 19 in Brussels who are not very active now.
Brussels, UccleAges 12–19 - NCT06294184Recruiting
Brain stimulation for mild depression in young people
This trial tests a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) to see if it can help young people with mild depression symptoms. It is designed for those who have some depressive feelings but do not yet meet the full criteria for major depression.
Guangzhou, GuangdongAges 12–25 - NCT06597695RecruitingPhase 1/Phase 2
Ketamine group therapy for Spanish-speaking adults with depression
This trial tests whether ketamine-assisted group therapy can help Spanish-speaking Latinx adults with major depression. You would receive ketamine in a supportive group setting, with the goal of improving your mood and quality of life.
Chelsea, MassachusettsAges 18–64 - NCT07423273Recruiting
Hyperbaric oxygen therapy for post-stroke depression
This study tests if breathing pure oxygen in a special chamber (hyperbaric oxygen therapy) can help people who have been depressed since having a stroke. It may offer a new way to treat depression that hasn't improved with standard medications.
ZrifinAges 50–85 - NCT06266715Recruiting
Testing ATP for depression relief
This trial tests if a natural compound called ATP can help improve moderate to severe depression symptoms. If you haven't taken antidepressants recently and have never tried escitalopram, you may be eligible.
Guangzhou, GuangdongAges 18–65 - NCT05691439Recruiting
Sleep Timing, Mood, and Brain Circuits in Teens With Depression
This study looks at how sleep timing affects brain function related to mood and “pleasure” in teenagers who have depressive symptoms. It may help researchers understand why depression and reduced interest/pleasure can happen, and how sleep patterns might be a key factor.
Eugene, OregonAges 14–18 - NCT05648175Recruiting
Test an AI coaching tool versus a care team for depression
This study compares an artificial intelligence (AI) decision-making approach with support from a multi-professional care team for treating depression. It aims to see which approach helps people make better treatment choices and manage symptoms.
Kingston, OntarioAges 18 years+ - NCT06424184Recruiting
Fast brain stimulation for addiction and depression
This study tests a quick, non-invasive brain stimulation method (rTMS) to help people who use stimulants like cocaine or methamphetamine and also feel depressed. The goal is to see if it can reduce cravings and improve mood.
Dallas, TexasAges 18–65 - NCT07373080Recruiting
Behavioral activation therapy for adults with depression
This trial tests a culturally adapted behavioral activation therapy to help adults with depression in primary care settings. It aims to improve both effectiveness and implementation of the therapy.
Sleman, Special Region of YogyakartaAges 18–65 - NCT07449676Recruiting
Tui Jing therapy for depression study
This study tests a gentle hands-on therapy based on Traditional Chinese Medicine, called Tui Jing, to see if it improves mood and brain function in people with depression. It lasts 12 weeks and compares the therapy with a placebo.
Hong Kong, Hung HomAges 18–55 - NCT06557525RecruitingPhase 1/Phase 2
Neurofeedback for depression: a research study
This early-phase trial tests whether a brain-training technique called neurofeedback can help reduce depression symptoms. It is for adults with major depression who are not at high risk for suicide or addiction.
FukuokaAges 18 years+ - NCT06400121RecruitingPhase 2
Apimostinel plus brain training for depression
This study tests if a new drug called apimostinel, combined with computer-based brain training exercises, can improve depression symptoms. It may help people with major depression who also have negative thoughts about themselves.
Pittsburgh, PennsylvaniaAges 18–60 - NCT05681767Recruiting
Lifestyle coaching to support depression care in primary clinics
This trial studies whether motivational, multi-part lifestyle coaching can help adults with depression when they start treatment through a regular primary care clinic. If you’re eligible, the program may add supportive skills to help improve mood alongside usual care.
KuopioAges 18 years+ - NCT07333027Recruiting
Loneliness in depression treatment study
This study looks at how loneliness affects people hospitalized for depression. It may help researchers understand how to better support recovery.
Erlangen, BavariaAges 18 years+ - NCT06797804Recruiting
Horticultural therapy for older adults in long-term care
This study tests if an app-guided gardening program can improve heart health, reduce stress and depression, and boost happiness in older adults living in nursing homes. It aims to see if these sessions can help you feel better overall.
TaipeiAges 65 years+ - NCT05456035Recruiting
Talk-therapy plus social skills training for depressed teens
This study tests whether adding social-cognitive training (skills for understanding social situations and thoughts) to regular talk therapy helps teens with depression. It may help improve mood and daily functioning compared with talk therapy alone.
Nashville, TennesseeAges 13–17 - NCT05570721Recruiting
Study of depression, stress, and heart health in late menopause
This study looks at how depression and stress connect to heart health in women going through the late stages of menopause. It may help researchers understand what factors affect heart risk during this life stage, including how symptoms and daily life relate to heart measurements.
Chapel Hill, North CarolinaAges 44–55 - NCT07293806Recruiting
Dance therapy for teens with depression
This study tests whether dance-movement therapy (moving with a therapist to express feelings) can help teens with moderate to severe depression feel better. It is for adolescents who are not experiencing other severe mental health conditions like psychosis or a critical substance use problem.
HelsinkiAges 13–17 - NCT04142996Recruiting
Comparing one- vs two-side brain stimulation for depression
This trial compares two versions of a noninvasive brain treatment called rTMS to see which side-to-side approach works better for major depression. You may be eligible if you still have moderate depressive symptoms despite trying at least one antidepressant.
Ottawa, OntarioAges 18 years+ - NCT06966921Recruiting
Brain stimulation for thinking, mood, and sleep in mental illness
This trial tests if a gentle electrical device placed on your head (cranial electrotherapy) can improve thinking, mood, and sleep for people living with chronic mental health conditions. It's a non-invasive approach that might help with anxiety or depression without medication side effects.
Nantou CityAges 20–75 - NCT07227389Recruiting
Opioid Timing and Breathing Risk After Surgery
This study looks at when opioids are given during surgery and how it affects breathing problems after surgery. It might help understand how to make pain control safer.
Detroit, MichiganAges 18–85 - NCT06517121Recruiting
Brain stimulation for mild depression
This trial tests whether a gentle brain stimulation technique called tDCS can help people with mild depression symptoms. It aims to improve mood without the need for medication.
Hong KongAges 18 years+
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Common questions
- Are there clinical trials for depressed?
- Yes. Clin2 currently lists 1,504 recruiting depressed studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depressed trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depressed trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.