Clinical trials · Illinois
Diabetes Mellitus clinical trials in Illinois
We’re tracking 41 recruiting diabetes mellitus studies with a site in Illinois — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Illinois
- NCT07521475Recruiting
Fully Closed Loop Insulin Pump for Type 2 Diabetes
This study tests a new automated insulin pump system (Omnipod) that adjusts insulin doses on its own throughout the day for people with type 2 diabetes. The goal is to see if it helps keep blood sugar levels more stable while reducing the burden of manual insulin management.
Chicago, IllinoisAges 18–75 - NCT05762107RecruitingPhase 2
Drug ZT-01 to reduce low blood sugar at night
This Phase 2 study tests ZT-01 to help prevent night-time low blood sugar (hypoglycemia) in people with type 1 diabetes. It may help if you’ve had low blood sugar during sleep or are at high risk based on recent glucose monitoring.
Chicago, IllinoisAges 18–75 - NCT01241864RecruitingPhase 2
Islet transplant for type 1 diabetes after kidney transplant
This trial tests whether transplanting insulin-producing “islet” cells can better control blood sugar in people who have already received a kidney transplant. It’s mainly for adults with type 1 diabetes whose body is no longer making enough insulin, while they are on kidney-transplant medicines.
Chicago, IllinoisAges 18–68 - NCT05415878Recruiting
Comparing removable boot designs for diabetic foot ulcers
This study compares different removable cast walkers (special boots) to see which is easier for people with diabetic foot ulcers to use. If you join, you'll try one of these boots and share your experience, which may help heal your ulcer while keeping you mobile.
North Chicago, IllinoisAges 18 years+ - NCT06217302RecruitingPhase 3
Sotagliflozin for kidney protection in type 1 diabetes
This study tests whether sotagliflozin (a pill that helps control blood sugar and protects the kidneys) can slow down kidney function decline in people with type 1 diabetes and diabetic kidney disease. You may qualify if you have had type 1 diabetes for at least 8 years, have moderate kidney damage, and are on standard treatments.
Chicago, IllinoisAges 18–75 - NCT07351058RecruitingPhase 3
Enicepatide for weight loss in people with type 2 diabetes
This trial tests an investigational medication, Enicepatide, to see if it helps people with obesity or overweight and type 2 diabetes lose weight and improve blood sugar control. You will receive weekly injections and regular check-ups.
Springfield, IllinoisAges 18 years+ - NCT06739122RecruitingPhase 3
A study of dulaglutide for children with type 2 diabetes
This trial tests if a weekly injection of dulaglutide (Trulicity) can help children with type 2 diabetes control their blood sugar when used together with metformin and/or insulin. It may be an option for kids who are overweight.
Chicago, IllinoisAges 10–17 - NCT07817251RecruitingPhase 3
Switching From Semaglutide to Cagrisema in Type 2 Diabetes
This study looks at how people with type 2 diabetes tolerate switching from a weekly semaglutide injection (like Ozempic or Wegovy) to a new experimental medicine called Cagrisema. The goal is to see if the switch is safe and effective.
Skokie, IllinoisAges 18 years+ - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Chicago, IllinoisAges 18 years+ - NCT04687215Recruiting
Spinal cord stimulation for painful diabetic nerve pain
This trial studies whether a spinal cord stimulator can reduce pain from diabetic nerve damage in the legs. It focuses on people with long-lasting type 2 diabetes and significant, treatment-resistant pain.
Chicago, IllinoisAges 18 years+ - NCT07743450RecruitingPhase 3
Daily oral medication for weight loss in adults with obesity and type 2 diabetes
This study tests a once-a-day pill for adults who are overweight or have obesity and also have type 2 diabetes. The goal is to see if the medication helps with weight loss and improves blood sugar control.
Schaumburg, IllinoisAges 18 years+ - NCT07784725RecruitingPhase 3
Study of a weight loss injection for adults with obesity
This study tests a new medicine to help adults with obesity or overweight lose weight. It's for people who have had trouble losing weight in the past and don't have diabetes.
Champaign, IllinoisAges 18 years+ - NCT07783802RecruitingPhase 2
Study of clazakizumab for adults with high inflammation and heart risk
This study tests whether clazakizumab can reduce the risk of heart attacks or strokes in people with high levels of inflammation (measured by a blood test called hsCRP) and conditions like heart disease, obesity, diabetes, high blood pressure, or kidney disease. If you qualify, you'll receive either the study drug or a placebo to see if it helps lower your risk.
Lombard, IllinoisAges 18 years+ - NCT07684144RecruitingPhase 3
Long-term study of a weight-loss medication for people who completed an earlier trial
This study tests the long-term effects of a medication called maridebart cafraglutide for weight management. It is for people who already completed a 72-week study of this drug and want to continue treatment.
Skokie, IllinoisAges 18–99 - NCT05555095Recruiting
Digital care programs for people on Medicaid
This trial tests a digital (phone or online) model for delivering healthcare for people who have Medicaid or qualify for both Medicare and Medicaid. It may help improve how care is organized and delivered for conditions like high blood pressure, diabetes, or pregnancy.
Peoria, IllinoisAges 18 years+ - NCT06950788Recruiting
Glucose changes in cirrhosis patients around liver transplant
This study looks at how the body processes sugar (glucose) in people with cirrhosis who are waiting for a liver transplant. It aims to track changes in blood sugar control before and after transplant, which may help improve care for patients with liver disease.
Chicago, IllinoisAges 18–75 - NCT06112418Recruiting
Personalized vs standard care to prevent heart attacks
This trial compares two ways to prevent heart attacks and strokes: one uses a special heart CT scan to guide care, the other uses standard risk factors like blood pressure and cholesterol. You may be eligible if you are older (men over 55, women over 65) and have diabetes, prediabetes, or metabolic syndrome.
Glenview, IllinoisAges 55 years+
Diabetes Mellitus trials by city in Illinois
Where these studies are running in Illinois
Institutions with a site for the recruiting diabetes mellitus studies listed above.
- Northwestern University · 3 studies
- University of Chicago Medical Center · 3 studies
- Endeavor Health · 2 studies
- Accellacare - DuPage
- Accellacare of Duly
- Accellacare of Duly - Lombard
- AURORA-2 Clinical Site
- Cedar Crosse Research Center
What taking part in a diabetes mellitus study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes Mellitus trials in other states
Common questions
- Are there diabetes mellitus clinical trials in Illinois?
- Yes. We're currently tracking 41 recruiting diabetes mellitus studies with a site in Illinois, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes mellitus study in Illinois?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Illinois to take part?
- Not necessarily. These studies have a site in Illinois, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes mellitus trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes mellitus studies open in Illinois regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.