Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,359 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06554301RecruitingPhase 1
Empagliflozin for pulmonary arterial hypertension study
This study tests if the diabetes drug empagliflozin can help people with pulmonary arterial hypertension (PAH), a condition causing high blood pressure in the lungs. It aims to see if the drug improves symptoms and is safe for patients with moderate symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06562569Recruiting
Non-invasive vagus nerve stimulation for Parkinson's gait issues
This study tests a non-invasive vagus nerve stimulation device to see if it can improve walking and reduce freezing of gait in people with Parkinson's disease. It is done at VA hospitals and involves wearing a device on the neck during walking tasks.
Hines, IllinoisAges 50–88 - NCT06565078Recruiting
Safety study of immune globulin for primary immunodeficiency
This study is a safety check for people with primary immunodeficiency who are already using a specific immune globulin treatment given under the skin. It looks at medical records to see if any side effects occurred.
Tokyo, TokyoAges Any age - NCT06557616Recruiting
CoolCryo system for treating atrial fibrillation during mitral valve surgery
This trial tests a new tool called CoolCryo that freezes heart tissue to treat atrial fibrillation while you have mitral valve surgery. If you are already having this surgery and also have AF, this device could correct both problems at once.
BydgoszczAges 18 years+ - NCT06549725Recruiting
Lipidica software for pancreatic cancer screening
This trial tests a software that analyzes fats (lipids) in your blood to find pancreatic cancer early. You may join if you have pancreatic cancer that can be removed with surgery, or if you are at very high risk due to family history or certain gene mutations.
Prague, CzechiaAges 18 years+ - NCT06557265RecruitingPhase 1/Phase 2
NKX019 for lupus kidney disease or membranous nephropathy
This trial tests an experimental cell therapy called NKX019 for people with active lupus nephritis (a type of kidney inflammation from lupus) or primary membranous nephropathy (another kidney condition) that hasn't gotten better after standard treatments. It may help if you have tried at least two treatments for lupus kidney disease or one for membranous nephropathy and still have active kidney disease.
Little Rock, ArkansasAges 18–75 - NCT06563895RecruitingPhase 3
Testing acoramidis to prevent ATTR amyloidosis in gene carriers
This trial tests a daily pill called acoramidis to see if it can prevent ATTR amyloidosis in people who carry a gene mutation but have no symptoms yet. It aims to stop the disease before it starts.
La Jolla, CaliforniaAges 18–75 - NCT06553625Recruiting
RF ablation study for pain or CNS conditions
This study observes how well a Boston Scientific radiofrequency (RF) system works for treating pain or central nervous system (CNS) conditions. It helps researchers understand real-world benefits for patients scheduled for this procedure.
CologneAges Any age - NCT02397668Recruiting
New tricuspid valve replacement for leaky or absent valve
This study tests a special replacement valve (an “ECM valve”) for people whose tricuspid valve is leaky or missing and needs surgery. It may help restore blood flow on the right side of the heart and is designed for certain children born with congenital heart problems.
Mobile, AlabamaAges 1–85 - NCT06553976Recruiting
Research network for hereditary spastic paraplegia
This trial aims to build a research network and gather information from people with two genetic types of hereditary spastic paraplegia (SPG4 and SPG5A). It will help doctors better understand these conditions and improve care.
Miami, FloridaAges Any age - NCT06565572Enrolling by invitationEarly Phase 1
Antisense drug for PCARP disease caused by FLVCR1 mutation
This trial tests a new drug called an antisense oligonucleotide (a type of genetic medicine) for people with a specific form of inherited eye disease called PCARP, which is caused by changes in the FLVCR1 gene. The goal is to see if the drug can slow or stop vision loss.
Aurora, ColoradoAges Any age - NCT06563544Recruiting
Two ventilator settings for asthma and COPD patients
This study compares two different ways of delivering breaths from a ventilator for people with severe asthma or COPD. The goal is to see which method might be better for your lungs.
Rotterdam, South HollandAges 18–100 - NCT06551662Recruiting
Balloon vs. stent for split artery blockages
This trial compares two ways to open a blocked artery that splits into two branches (a bifurcation): using a balloon coated with medicine (drug-coated balloon, or DCB) versus a drug-eluting stent (DES). The goal is to see which approach works better for patients with this type of blockage.
MilanAges 18 years+ - NCT06555965Recruiting
STXBP1 and SYNGAP1 natural history study
This study follows people with STXBP1 or SYNGAP1 gene changes over time to learn more about how these conditions affect the body and mind. It does not test a treatment but helps researchers understand the natural course of the disorder.
Palo Alto, CaliforniaAges Any age - NCT06561880RecruitingPhase 1/Phase 2
Three-drug combo for FLT3-mutated AML
This trial is testing a three-drug combination for people newly diagnosed with a type of AML that has a FLT3 mutation. The goal is to see if this treatment works better than standard care.
Tianjin, Tianjin MunicipalityAges 14 years+ - NCT06550115Recruiting
Night shift workers and their blood vessel & sugar health
This trial studies how sleep patterns affect blood vessel health and sugar control in long-term night shift workers. It may help find better ways to prevent heart problems and diabetes.
Fort Collins, ColoradoAges 18–65 - NCT06555029Recruiting
Oral health help for older adults on Medicaid
This trial is testing an oral health program offered during routine primary care visits for older adults (55+) on Medicaid. It aims to see if adding dental care support to regular check-ups can improve health.
Cleveland, OhioAges 55 years+ - NCT06562179Recruiting
Robotic surgery for stomach, pancreas, liver, bile duct, and esophagus conditions
This study is testing a new robotic system for several types of abdominal surgeries. Depending on your diagnosis, you may qualify for a specific part of this trial that looks at how well this robot can help with your operation.
Tampa, FloridaAges 18–80 - NCT06566105Recruiting
Fatty liver study for blood donors with weight concerns
This study collects blood samples from donors with excess weight or related health issues to better understand fatty liver disease. If you are a blood donor between 40 and 65, and have overweight, high blood sugar, abnormal cholesterol, or high blood pressure, you may be able to help.
Milan, MilanoAges 40–60 - NCT06566196Recruiting
Heart exercise testing for congenital heart disease
This study tests how well your heart pumps during exercise while you are undergoing a heart catheter procedure. It may help doctors better understand your heart function and guide your treatment.
Rochester, MinnesotaAges 18 years+ - NCT06560801RecruitingPhase 4
Dapagliflozin for kidney health after transplant
This trial tests whether taking dapagliflozin (a drug often used for diabetes and heart health) can help improve kidney structure and blood flow in people who received a kidney transplant at least 9 months ago. It may benefit those whose kidney function is stable, regardless of whether they have diabetes.
Erlangen, BavariaAges 18–75 - NCT05698810Recruiting
Study exams practice for upcoming research
This trial checks whether it’s practical and workable to set up study-related exams before planned research. It mainly recruits adults who can consent and be contacted, so the team can prepare future studies smoothly.
GrenobleAges 18 years+ - NCT06114732Recruiting
Walking improvement study for leg pain from PAD
This study tests if a combination of a behavioral program and electrical stimulation (TENS) can help people with peripheral artery disease walk farther with less pain. It aims to boost physical activity and quality of life.
Glasgow, LanarkshireAges 18 years+ - NCT05742906Recruiting
Tricuspid valve repair using a new replacement valve patch
This trial studies a new valve replacement device (the Cor TRICUSPID ECM Valve) for people whose right-sided tricuspid valve is leaking or missing and needs surgery. It may help restore proper one-way blood flow in the heart, but you must meet several heart, blood, and organ-health requirements.
Indianapolis, IndianaAges Any age
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,359 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.