Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07285720Recruiting
Language Development in Williams Syndrome
This study looks at how children and adults with Williams syndrome learn language. Researchers want to understand how sounds and word patterns affect language skills in this condition.
AmiensAges 6 years+ - NCT07287267Recruiting
Knee pain and movement study for young adults
This study looks at how knee movement during rehabilitation exercises relates to pain in people with kneecap pain (patellofemoral pain syndrome). It aims to help understand better ways to recover.
KalmarAges 15–35 - NCT07290257RecruitingPhase 4
Long-term safety study of Livmarli for Alagille syndrome or PFIC
This study looks at the long-term safety and effects of Livmarli (maralixibat) in children with Alagille syndrome or progressive familial intrahepatic cholestasis (PFIC). It may help understand how well the medicine works over time for itching and other symptoms.
BrusselsAges 2 months+ - NCT07291609Recruiting
Microplastics in heart artery patients
This study looks for tiny plastic particles in the blood of people with chronic heart artery disease. You will have a standard CT scan and an invasive angiogram anyway, and researchers will check your blood samples for microplastics.
CasertaAges 18 years+ - NCT07293897Recruiting
Study of Livmarli for Alagille Syndrome and PFIC
This study looks at how well Livmarli works for people with Alagille syndrome or a liver disease called PFIC. It uses data from prescriptions to understand the treatment's effects.
Tokyo, TokyoAges Any age - NCT07294157Recruiting
Splint vs Laser Therapy for Carpal Tunnel Syndrome
This study compares wearing a wrist splint to high-intensity laser therapy for treating carpal tunnel syndrome. It may help you if you have mild to moderate symptoms and haven't had recent treatments.
AfyonkarahisarAges 18–75 - NCT07295691Recruiting
Autologous serum eye drops for dry eye
This trial tests whether eye drops made from your own blood can help treat moderate to severe dry eye that hasn't improved with artificial tears.
CairoAges Up to 18 years - NCT07296861Recruiting
Home program for healthy growth in children with Down syndrome
This study tests a family-based program you can do at home to help your young child with Down syndrome develop healthy habits. It aims to support your child's growth and well-being through fun activities and guidance.
Chapel Hill, North CarolinaAges Any age - NCT07298564Recruiting
Magnesium and levocarnitine for PCOS symptoms
This trial tests whether taking magnesium and levocarnitine (a natural substance that helps cells make energy) can improve metabolism and reduce symptoms like irregular periods or weight gain in women with polycystic ovary syndrome (PCOS). If you have PCOS, you may be able to join.
Tehran, Tehran ProvinceAges 19–65 - NCT07306988RecruitingPhase 4
Treating H. pylori to improve metabolic syndrome
This trial tests whether treating H. pylori infection can help improve metabolic syndrome (a group of conditions like high blood sugar, abnormal cholesterol, and high blood pressure). It aims to understand how treatment changes your gut bacteria and overall health.
Nanjing, JiangsuAges 18–65 - NCT07312123Recruiting
Vitamin mix for carpal tunnel recovery
This trial tests if taking a mix of vitamins can help adults heal better after surgery for carpal tunnel syndrome. It might help reduce pain and improve hand function.
Kubang Kerian, KelantanAges 18 years+ - NCT07312864RecruitingPhase 1/Phase 2
New bioartificial liver for liver failure and small-for-size syndrome
This study tests a new bioartificial liver made from special cells to support people with severe liver problems, including liver failure or when the liver is too small after surgery. It aims to see if it is safe and can help the liver recover.
BeijingAges Any age - NCT07314008Recruiting
Comparing pacing methods for slow heartbeat with long AV delay
This trial tests two types of heart pacing to see which works better for people with a slow heartbeat from sinus node issues and a long delay between the upper and lower heart chambers (PR interval over 200 ms). The goal is to find the best way to pace the heart while keeping unnecessary pacing minimal.
Seoul, Songpa-guAges 18 years+ - NCT07318987Recruiting
Nerve release surgery for knee pain relief
This study tests if surgically releasing a nerve in the knee (the saphenous nerve) can reduce pain in people with patellofemoral pain syndrome (pain around the kneecap). If you've had anterior knee pain for at least six weeks and the nerve test is positive, this trial may offer relief.
CairoAges 18–35 - NCT07319832Recruiting
Teduglutide study for children with short bowel syndrome
This trial tests the medicine teduglutide in children (ages 1–17) with Short Bowel Syndrome who need IV nutrition. The goal is to see if teduglutide can help them reduce or stop IV nutrition.
Guangzhou, GuangdongAges 1–17 - NCT07324005Recruiting
Ultrasound-guided carpal tunnel release and injection for carpal tunnel syndrome
This trial tests a new treatment for carpal tunnel syndrome that uses ultrasound to guide a needle to release a tight ligament in the wrist and inject a sugar-water solution around the nerve. This may help relieve pain and numbness without surgery.
TaipeiAges 20–80 - NCT07329699Recruiting
AI-Guided Heart Artery Pressure Test vs Standard Test
This study compares a new artificial intelligence (AI) method to measure blood flow in your heart arteries (called Medipixel FFR) with the standard invasive method. If you are scheduled for a heart angiogram or stenting and have a moderate blockage (40-90% narrowing) that doctors are unsure about, this AI tool may help decide the best treatment for you.
Seoul, Select StateAges 19 years+ - NCT07330297Recruiting
Breath test for metabolic syndrome and obesity health
This study uses a breath test to see if it can tell the difference between people with metabolic syndrome, those with obesity but otherwise healthy, and healthy controls. It aims to find a simple way to check metabolic health without blood draws.
MoscowAges 18 years+ - NCT07334912RecruitingPhase 2
Study of AEF0217 for people with Down syndrome
This study tests if an investigational drug called AEF0217 can help improve thinking and daily living skills in people with Down syndrome. It's for ages 16-32 who have a caregiver to support them throughout the trial.
BordeauxAges 16–32 - NCT07339930Recruiting
Understanding PCOS types in women
This study looks at the different types of PCOS (polycystic ovary syndrome) in women who are seen at the Strasbourg University Hospital. It aims to better understand the condition and its features.
StrasbourgAges 18–49 - NCT07339904Recruiting
Bowel Function After Rectal Cancer Surgery
This study follows people with rectal cancer who have surgery to remove part of the rectum. It looks at how bowel function changes over time, and whether different treatments before surgery affect recovery.
Edegem, AntwerpAges 18 years+ - NCT07342205RecruitingPhase 2/Phase 3
Fecal transplant for sepsis-related lung injury
This study tests if transferring healthy gut bacteria (fecal microbiota transplant) can help people with acute lung injury caused by sepsis. It aims to reduce inflammation and improve breathing.
Shanghai, PutuoAges 18 years+ - NCT07344012Recruiting
Parenting hopes in women with Turner syndrome
This study looks at women with Turner syndrome who wanted to become parents. It aims to understand what support they received and what happened with their parenting plans.
StrasbourgAges 18–40 - NCT07598422Recruiting
Safety and Effectiveness of Canakinumab for Schnitzler's Syndrome
This study tracks how well and safely canakinumab (a medication that reduces inflammation) works in patients newly diagnosed with Schnitzler's syndrome. Schnitzler's syndrome is a rare condition causing recurring fevers, rashes, and joint pain, and this study helps doctors understand how this drug performs in real-world use.
Kanoya, Kagoshima-kenAges birth+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.