Clinical trials
Drug Resistance clinical trials
Below are recruiting drug resistance clinical trials, each written for real people, not researchers. We’re tracking 122 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06210022Recruiting
Cognitive problems in drug-resistant vs drug-responsive epilepsy
This study compares thinking skills in people with focal epilepsy that responds well to medication versus epilepsy that doesn't. It aims to understand how different types of epilepsy affect memory, attention, and other cognitive functions.
MilanAges 18–60 - NCT07035535Enrolling by invitation
Using genetic tests to predict antibiotic resistance in lung infections
This trial looks at whether a special genetic test (tNGS) can predict which antibiotics will work for bacteria causing lung infections. It may help doctors choose the right treatment faster.
Nanjing, JiangsuAges 18 years+ - NCT07010445Recruiting
Gut-brain connection in resistant epilepsy
This study looks at how the gut and brain talk to each other in people with epilepsy, especially when seizures are hard to control. It may help find new ways to treat epilepsy by focusing on the gut.
Milan, LombardyAges 3–50 - NCT02543866RecruitingPhase 1
Fecal transplant to clear resistant gut bacteria in children
This Phase 1 study tests whether transferring stool microbiome (a fecal microbiota transplant) can help clear antibiotic-resistant bacteria living in the gut. It’s meant for children and teens who have had infections from these resistant bacteria and who can safely take the study’s planned treatment.
Seattle, WashingtonAges 7–21 - NCT05835206RecruitingPhase 2
Drug to reduce antibiotic-resistant gut bacteria
This Phase 2 study tests whether an investigational treatment can help clear or reduce antibiotic-resistant bacteria living in the gut. It may help prevent these germs from causing future infections by targeting specific resistant bacteria found on stool or rectal swabs.
Atlanta, GeorgiaAges 18 years+ - NCT01212003Recruiting
Study of how tuberculosis develops over time
This study follows people with suspected or confirmed tuberculosis (TB), whether they have inactive “latent” TB or active TB. It helps researchers better understand TB’s natural course and may improve future testing and care by allowing collection and storage of samples.
Bethesda, MarylandAges 2–100 - NCT06406608Recruiting
Personalized drug test for drug-resistant lung cancer
This trial tests a new way to choose your next treatment by growing a mini version of your tumor (an organoid) in a lab and seeing which drugs kill it best. It is for people with drug-resistant non-small cell lung cancer who have already tried at least two standard treatments.
Zhengzhou, HenanAges 18–75 - NCT06321536RecruitingPhase 2
Testing microbiota therapy for resistant bacteria in the gut
This study tests a treatment made from healthy donor stool (called microbiota therapy) given as an enema or through a feeding tube. It aims to help people who carry resistant bacteria that are hard to treat, by reducing or clearing those bacteria from the gut.
Atlanta, GeorgiaAges 18 years+ - NCT07183748RecruitingPhase 2
Psilocybin microdosing plus therapy for hard-to-treat depression
This trial tests whether taking very small, repeated doses of psilocybin (a substance found in magic mushrooms) along with talk therapy can help people with depression that hasn't gotten better with other treatments. You'll need to stop your current depression medications and avoid drugs or alcohol for the study period.
BeershebaAges 18–65 - NCT06476210RecruitingPhase 4
New drug combo for drug-resistant tuberculosis
This trial tests a three-drug combination (bedaquiline, delamanid, and linezolid) to see if it's safe and works well for people with multi-drug resistant or rifampicin-resistant tuberculosis. It may offer a new treatment option if standard drugs aren't working.
Hefei, AnhuiAges 18 years+ - NCT06843668RecruitingPhase 2/Phase 3
Best ways to give colistin for tough infections in the ICU
This study tests different ways of giving the antibiotic colistin to patients in the ICU with infections that are hard to treat. The goal is to find the best dosing schedule to help you fight the infection more effectively.
BuraidahAges 18 years+ - NCT05798364Recruiting
Study how resistant gut bacteria spread within households
This study tracks a specific kind of antibiotic-resistant gut bacteria in hospital patients and how it may spread to people living in the same home. It may help researchers understand transmission risk inside households and improve prevention strategies.
Paris, Île-de-France RegionAges Any age - NCT05022238Recruiting
Screening for drug-resistant TB hotspots in Namibia
This study tries to find more cases of drug-resistant tuberculosis (TB that doesn’t respond to usual medicines) by checking people in specific regions, households, hospitals, and high-risk “hotspots.” It may help detect TB earlier and link more people to treatment.
WindhoekAges Any age - NCT04098315Recruiting
HIV drug-resistance patient registry study for people 14+
This study is a registry (a way to collect and organize information) for people living with HIV who have drug-resistant virus. It may help researchers better understand how resistant HIV behaves and how to manage treatment over time.
Milan, MIAges 14 years+ - NCT07071103RecruitingPhase 2
Low-dose radiation and immunotherapy for resistant solid tumors
This trial tests a combination of low-dose radiation to the intestines and immunotherapy for people whose cancer has stopped responding to standard treatments including immunotherapy. It may offer a new option when other therapies have failed.
Shantou, GuangdongAges 18–80 - NCT07073755Recruiting
Study of next treatments after targeted therapy resistance for advanced breast cancer
This study looks at what happens when people with advanced breast cancer switch to a new treatment after their cancer becomes resistant to targeted therapies like CDK4/6 inhibitors, PIK3CA inhibitors, or T-DXd. Researchers want to understand which next treatments work best in real life.
Changsha, HunanAges 18 years+ - NCT06232213Recruiting
Personalized treatment for relapsed or drug-resistant gynecological cancers
This trial tests a personalized approach to treating advanced ovarian or endometrial cancers that have come back or stopped responding to standard treatments. It uses a special model to guide which therapy might work best for you.
Beijing, Beijing MunicipalityAges 18–80 - NCT04172025Recruiting
Swiss database for tracking hard-to-treat infections
This study builds a Swiss database using lab genetic testing (whole genome sequencing) plus basic patient information to track outbreaks of serious, drug-resistant, and sometimes high-infectious pathogens. Your data could help researchers understand how these germs spread and how to better prevent them.
BaselAges Any age - NCT07237971Recruiting
Making medicine use better in Elche
This study works with the community to find ways to use medications like antidepressants, blood pressure drugs, and antibiotics more wisely. It is a collaboration among residents, healthcare workers, and local groups to create solutions together.
Elche, AlicanteAges 18 years+ - NCT06209645Recruiting
Personalized brain stimulation for stubborn nerve pain relief
This study tests a non-invasive, personalized brain stimulation technique to reduce nerve pain that has not responded to standard treatments. It may be a good option if you have had nerve pain for over a year and have already tried other pain medications without enough relief.
BronAges 18–80 - NCT07134270Recruiting
Digestive bacteria and infection risk in hospitalized patients
This study looks at whether patients in the hospital who carry certain resistant bacteria in their gut are more likely to get infections. The goal is to understand the risk so doctors can better protect you.
Bucharest, BucharestAges 18 years+ - NCT06022055Recruiting
studying brain tissue from epilepsy surgery
This study collects brain tissue from people with epilepsy that is not controlled by medication, during their planned surgery. Researchers will study the tissue to better understand epilepsy and improve treatments.
ParisAges 18 years+ - NCT07189364Enrolling by invitation
Comparing antibiotic prescribing to help doctors improve
This trial tests whether giving doctors a report comparing their antibiotic prescribing to their peers can improve how antibiotics are used. If you are a general medicine patient who stayed in the hospital for a short time, this study may help make antibiotic use safer and more effective.
Toronto, OntarioAges 18 years+ - NCT06782880Recruiting
Fecal transplant to prevent infections after liver transplant
This study tests if giving a fecal transplant (a procedure that transfers healthy bacteria from a donor's stool into your gut) before a liver transplant can lower the risk of serious infections after the surgery. It might help strengthen your immune system to fight off germs.
BolognaAges 18 years+
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Common questions
- Are there clinical trials for drug resistance?
- Yes. Clin2 currently lists 122 recruiting drug resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a drug resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a drug resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.