Clinical trials
Drug Resistance clinical trials
Below are recruiting drug resistance clinical trials, each written for real people, not researchers. We’re tracking 118 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07507201RecruitingEarly Phase 1
Car-T cells for autoimmune diseases like lupus
This trial tests whether specially-engineered immune cells (CAR-T cells) can help people with certain autoimmune diseases that haven't gotten better with standard treatments. The cells are designed to target and remove faulty B cells that are causing the immune system to attack the body.
Hangzhou, ZhejiangAges 3 years+ - NCT06779864Recruiting
Hepatitis B virus genetics and drug resistance study
This study looks at how hepatitis B virus changes in your body, including mutations and drug resistance, using your blood or liver tissue samples. Understanding these changes could help improve treatment for hepatitis B.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06782880Recruiting
Fecal transplant to prevent infections after liver transplant
This study tests if giving a fecal transplant (a procedure that transfers healthy bacteria from a donor's stool into your gut) before a liver transplant can lower the risk of serious infections after the surgery. It might help strengthen your immune system to fight off germs.
BolognaAges 18 years+ - NCT06663969Recruiting
Temporal Interference Stimulation for Epilepsy
This trial tests a new, gentle way to stimulate specific brain areas using a special electrical signal. It aims to see if this can help people with epilepsy that hasn't improved with medication.
Beijing, Beijing MunicipalityAges 14–65 - NCT07399327Recruiting
SEEG thermocoagulation for hard-to-treat epilepsy
This study is looking at how well a procedure called SEEG thermocoagulation (a way to stop seizures by heating a small area of brain tissue) works for people with epilepsy that doesn't improve with medication. By joining, you will help doctors understand why this treatment works for some people and not others.
MarseilleAges 12 years+ - NCT06863350Recruiting
Closing a heart hole to treat drug-resistant epilepsy
This trial tests if closing a small hole in the heart (called a PFO) can reduce seizures in people whose epilepsy isn't controlled by medication. It might offer a new treatment option for those who have both drug-resistant epilepsy and this heart condition.
Chengdu, SichuanAges 18–60 - NCT07305116RecruitingPhase 1
CAR T-cell therapy for autoimmune diseases
This trial tests a new immune therapy called CAR T-cells that target two proteins (CD19 and BCMA) to treat autoimmune diseases like lupus, nephrotic syndrome, and others. It is for people whose standard treatments have not worked well enough.
Hangzhou, ZhejiangAges 3 years+ - NCT05527093Recruiting
Brain-scan study mapping social thinking changes in epilepsy
This study uses special thinking and brain-scanning tests to understand how “social thinking” may change in people with certain types of epilepsy. You might benefit by having a detailed evaluation during your planned pre-surgery workup.
Gif-sur-YvetteAges 18–65 - NCT07249034Recruiting
How epilepsy affects brain chemicals and breathing
This study looks at how epilepsy affects a chemical in the brainstem that helps control breathing and alertness. It uses a special PET scan and breathing tests to measure this in people with hard-to-control seizures.
BronAges 18–55 - NCT07244328RecruitingEarly Phase 1
UX-GIP001 cell therapy for drug-resistant temporal lobe epilepsy
This trial tests a new cell therapy, UX-GIP001, for people whose seizures start in one small area of the brain (the mesial temporal lobe) and are not controlled by at least two seizure medications. The goal is to see if this treatment can safely reduce seizures.
Hangzhou, ZhejiangAges 18–75 - NCT07237971Recruiting
Making medicine use better in Elche
This study works with the community to find ways to use medications like antidepressants, blood pressure drugs, and antibiotics more wisely. It is a collaboration among residents, healthcare workers, and local groups to create solutions together.
Elche, AlicanteAges 18 years+ - NCT07209761RecruitingPhase 3
New drug combo for drug-resistant TB (quabodepistat)
This study tests a new oral medication combination (quabodepistat with other drugs) for people with drug-resistant pulmonary TB. It aims to find a shorter, safer, and more effective treatment.
Beijing, Beijing MunicipalityAges 14 years+ - NCT07189364Enrolling by invitation
Comparing antibiotic prescribing to help doctors improve
This trial tests whether giving doctors a report comparing their antibiotic prescribing to their peers can improve how antibiotics are used. If you are a general medicine patient who stayed in the hospital for a short time, this study may help make antibiotic use safer and more effective.
Toronto, OntarioAges 18 years+ - NCT07145489Recruiting
Infrared light therapy for seizures
This trial tests whether shining a special infrared light on the scalp can reduce seizures in adults with epilepsy that is not controlled by standard medications. You would receive the light treatments and keep a diary of your seizures.
Boston, MassachusettsAges 18 years+ - NCT07147309Recruiting
PET scans for epilepsy surgery planning
This trial tests three types of PET scans to help doctors exactly locate the part of the brain causing seizures before surgery. It's for people with epilepsy that isn't controlled by medication and who are already planning surgery or an SEEG.
Fuzhou, FujianAges 18–50 - NCT07134270Recruiting
Digestive bacteria and infection risk in hospitalized patients
This study looks at whether patients in the hospital who carry certain resistant bacteria in their gut are more likely to get infections. The goal is to understand the risk so doctors can better protect you.
Bucharest, BucharestAges 18 years+ - NCT07110688Recruiting
Brain sensing study for mental states
This trial uses sensors and machine learning to understand mental states in healthy adults and people with epilepsy. Researchers aim to improve how we monitor and support mental health.
Downey, CaliforniaAges 18 years+ - NCT04172025Recruiting
Swiss database for tracking hard-to-treat infections
This study builds a Swiss database using lab genetic testing (whole genome sequencing) plus basic patient information to track outbreaks of serious, drug-resistant, and sometimes high-infectious pathogens. Your data could help researchers understand how these germs spread and how to better prevent them.
BaselAges Any age - NCT07095933RecruitingEarly Phase 1
Everolimus for hard-to-control focal epilepsy
This study tests whether the medicine everolimus (taken as a pill) can safely reduce seizures in adults with focal epilepsy that hasn't been controlled by other treatments. You would continue your current seizure medicines and add everolimus.
Beijing, Beijing MunicipalityAges 18–60 - NCT04977791Recruiting
Study how drug resistance develops in lung cancer immunotherapy
This study looks at lung tumor tissue and blood to understand why immune checkpoint drugs can stop working in non-small cell lung cancer. It may help researchers find better ways to predict and overcome drug resistance.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07052604Recruiting
Antibiotic treatment for a rare pneumonia in ICU patients
This study looks at how well antibiotics work for pneumonia caused by a specific bacterium (Stenotrophomonas maltophilia) in patients who are on breathing machines in the intensive care unit (ICU). It will help doctors choose the best treatment.
Saint-Denis, FranceAges 18 years+ - NCT07029932RecruitingPhase 1
Testing the safety of multiple doses of BWC0977 in healthy people
This study tests an experimental antibiotic called BWC0977 to see if it is safe and well-tolerated when given as single and multiple doses. It is for healthy volunteers to understand how the drug behaves in the body before moving to patient trials.
Melbourne, VictoriaAges 18–55 - NCT07013331Recruiting
Brain scan study for Dravet syndrome
This study uses a special PET-MRI scan to look at a brain chemical pathway linked to serotonin (a mood-regulating substance) in people with Dravet syndrome or certain types of epilepsy, and in healthy volunteers. It may help understand how the brain works in these conditions.
Bron, RhoneAges 18–60 - NCT05339438Recruiting
Brain scan mapping before epilepsy surgery
This study uses a special MRI scan to map parts of the front-temporal brain in people with drug-resistant epilepsy who may need surgery. The goal is to better plan surgery by showing which brain areas are involved.
NancyAges 18 years+
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Common questions
- Are there clinical trials for drug resistance?
- Yes. Clin2 currently lists 118 recruiting drug resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a drug resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a drug resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.