Clinical trials
Drug Resistance clinical trials
Below are recruiting drug resistance clinical trials, each written for real people, not researchers. We’re tracking 115 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07680842Recruiting
Non-invasive ultrasound for drug-resistant epilepsy
This study tests a non-invasive focused ultrasound treatment for people with epilepsy that doesn't respond to medications. The goal is to see if this gentle ultrasound can reduce seizures without surgery.
San Francisco, CaliforniaAges 21–65 - NCT06292494Recruiting
Focused ultrasound for drug-resistant epilepsy
This trial tests whether focused ultrasound can help people whose seizures are not controlled by two or more medications. You would have a noninvasive procedure while awake, pressing a stop button if needed, and your hair will be partially shaved.
TaipeiAges 18 years+ - NCT04126369Recruiting
Mindfulness program to improve quality of life in drug-resistant epilepsy
This trial tests whether a mindfulness training program can improve quality of life for people with drug-resistant epilepsy. It looks at whether learning mindfulness skills helps you cope day-to-day alongside your usual treatment.
GrenobleAges 18 years+ - NCT07640191Recruiting
New Nerve Stimulation Device for Hard-to-Treat Epilepsy
This study tests a new implanted device that stimulates the vagus nerve (a major nerve in your neck) to help reduce seizures in people whose epilepsy doesn't respond well to medications. The device is surgically placed under the skin and may help lower how often you have seizures.
Herston, QueenslandAges 4–75 - NCT05670847RecruitingPhase 2/Phase 3
Ketone drinks for drug-resistant epilepsy
This trial tests whether taking “ketone ester” supplements can reduce seizures in people with drug-resistant epilepsy. It may help by changing how the brain uses energy, but you must meet several safety and diet-related conditions.
SohagAges 1–16 - NCT07094984Recruiting
Clearing resistant gut bacteria: three FMT methods
This trial tests three different ways to clear antibiotic-resistant bacteria from your gut using fecal microbiota transplant (FMT). It may help if you have a confirmed resistant infection and are looking for a treatment to reduce the risk of future infections.
WarsawAges 18 years+ - NCT06708143Recruiting
Temporal interference therapy for drug-resistant epilepsy
This study tests a new, non-invasive treatment called 'temporal interference' for people whose epilepsy seizures are not controlled by medication. It aims to reduce seizures by using low-level electrical fields to calm overactive brain cells.
Beijing, Beijing MunicipalityAges 6–60 - NCT06492720Recruiting
Testing focused ultrasound for drug-resistant epilepsy
This study tests a new device called NaviFUS that uses focused sound waves to gently stimulate a small area of the brain. It is for people whose seizures start in one part of the brain and are not fully controlled by seizure medicines.
TaipeiAges 18–65 - NCT06388707RecruitingPhase 1/Phase 2
Ultrasound therapy for drug-resistant temporal lobe epilepsy
This study tests if a new, non-invasive ultrasound treatment can safely reduce seizures in people whose seizures start in the temporal lobe and have not been controlled by at least two anti-epileptic drugs. The ultrasound is delivered through the scalp to gently stimulate the brain area where the seizures begin.
Palo Alto, CaliforniaAges 18 years+ - NCT06590428Recruiting
Tracking linezolid levels for rifampin-resistant TB treatment
This study checks if measuring the amount of linezolid medicine in your blood helps treat rifampin-resistant tuberculosis more safely and effectively. It is for people who have already started a treatment plan that includes linezolid.
East London, Eastern CapeAges 18 years+ - NCT06334952Recruiting
Personalized brain stimulation for hard-to-treat epilepsy
This study tests a personalized, non-invasive brain stimulation method called tDCS for people with drug-resistant epilepsy that starts in one part of the brain. It aims to reduce seizures in those who cannot have surgery or have not been helped by surgery.
BordeauxAges 9 years+ - NCT05553236Recruiting
Using gene testing to guide treatment for drug-resistant tuberculosis
This study uses next-generation gene testing to help manage active drug-resistant tuberculosis. It may help doctors choose the most appropriate treatment by better identifying the TB’s drug resistance.
Cape TownAges Any age - NCT02890641Recruiting
Study of brain signals and genes in hard-to-treat epilepsy
This study looks at genetic factors and brain electrical activity in children whose seizures are difficult to control with standard medicines. It also involves exams like MRI and possibly procedures under anesthesia, to better understand seizure causes and help future care.
ParisAges 3 months–25 years - NCT06037564Enrolling by invitationPhase 4
Switching HIV treatment to a simpler daily pill
This study tests whether switching your current HIV medication to a daily pill with doravirine, dolutegravir, and lamivudine is safe and effective. It is for people whose HIV is well-controlled but who have had to change treatment before because it stopped working.
Aarau, Canton of AargauAges 18 years+ - NCT06248333Recruiting
Deep brain stimulation for focal motor epilepsy
This trial tests whether deep brain stimulation of a small area in the brain can help reduce seizures that start in the motor part of the brain and do not respond to medication. It may be an option for people who cannot have surgery or whose surgery did not help enough.
Beijing, Beijing MunicipalityAges 14–65 - NCT05947656Recruiting
NaviFUS treatment for drug-resistant temporal lobe seizures
This trial tests the NaviFUS system to treat seizures that keep happening despite seizure medicines, specifically in people with temporal lobe epilepsy. If you qualify, you would be carefully checked before and during the study, including seizure tracking and brain scans, to see whether treatment helps reduce seizures.
Melbourne, VictoriaAges 18 years+ - NCT07477119RecruitingPhase 4
Personalized linezolid dosing for drug-resistant TB treatment
This trial tests whether adjusting the dose of linezolid based on regular blood tests can help people with multidrug-resistant tuberculosis (MDR-TB) tolerate the medication better while on the BPaL or BPaL-M regimen. It aims to reduce side effects and improve treatment success.
ConakryAges 15 years+ - NCT07643948Recruiting
How HIV Treatment Changes Affect Drug Resistance
This study follows people with HIV whose virus is well-controlled on current medications to understand how switching to a different HIV drug regimen affects the virus's ability to resist those drugs. The goal is to help doctors choose the safest treatment switches.
Hong Kong, Hong KongAges 18 years+ - NCT06557720Recruiting
Imaging study for hard-to-control epilepsy
This study looks at how different brain scans (like MRI, PET, and EEG) can help find the exact spot where seizures start in people whose epilepsy hasn't been controlled by medicines. It aims to better understand drug-resistant epilepsy so doctors can plan more accurate treatments.
Xi'anAges 18–65 - NCT04923958Recruiting
Testing new TB screening and diagnostic tests
This study tests rapid TB screening and lab-style diagnostic methods to see how well they find TB disease and TB that is resistant to rifampin (a key TB drug). It may help doctors diagnose TB faster and more accurately, especially in people at higher risk.
TbilisiAges 12 years+ - NCT07823465Enrolling by invitation
Brain device study for teens with focal epilepsy
This study looks at how well an implanted brain device works for teenagers with focal epilepsy that doesn't improve with medicine. The device sends small electrical pulses to specific brain areas to reduce seizures, and this study will help learn if it's safe and helpful for teens.
Waltham, MassachusettsAges 13–19 - NCT05561504Recruiting
Study of stomach bacteria resistance in adults
This study looks at how common a stomach bacteria infection is and which antibiotics still work. You may help researchers by providing consent for related study participation and sample tracking.
MunichAges 18 years+ - NCT06210022Recruiting
Cognitive problems in drug-resistant vs drug-responsive epilepsy
This study compares thinking skills in people with focal epilepsy that responds well to medication versus epilepsy that doesn't. It aims to understand how different types of epilepsy affect memory, attention, and other cognitive functions.
MilanAges 18–60 - NCT07486024RecruitingPhase 3
A new 6-month treatment for multidrug-resistant tuberculosis
This trial tests a new 6-month treatment for people with multidrug-resistant tuberculosis (MDR-TB). It aims to see if this shorter treatment works well and can be used in France, offering a quicker option for recovery.
AmiensAges 18 years+
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Common questions
- Are there clinical trials for drug resistance?
- Yes. Clin2 currently lists 115 recruiting drug resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a drug resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a drug resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.