Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,377 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03918408RecruitingPhase 1
Platinum eye drops and light to slow keratoconus
This Phase 1 study tests whether a specific corneal cross-linking system (called PXL-Platinum 330) is safe and effective for people with progressive keratoconus, a condition that makes the cornea thin and bulge. The goal is to slow vision changes and see how well the treatment works in the short term.
Eugene, OregonAges 12–45 - NCT06451562Recruiting
Pain relief methods after scoliosis surgery
This trial compares two ways to manage pain after scoliosis surgery: numbing the area near the spine (regional anesthesia) or giving lidocaine through an IV. The goal is to see which method reduces the need for morphine after surgery.
Be’er Ya‘aqovAges 12–25 - NCT06533137Recruiting
How your mind can influence the placebo effect
This trial studies how your awareness and personal beliefs affect the placebo effect—a real improvement in symptoms from a treatment that has no active medicine. Researchers are looking at healthy people to understand how the mind and body interact, which could help improve future treatments.
MilanAges 18 years+ - NCT06671665Recruiting
Manual therapy for low back pain in women with osteopenia
This study tests if manual therapy (hands-on treatment by a therapist) can reduce low back pain in postmenopausal women who have osteopenia, a condition where bones are weaker than normal but not yet osteoporosis. It aims to help with pain located in the lower back area.
GizaAges 50–60 - NCT06685367Recruiting
AI software for predicting acute kidney injury in ICU
This trial tests software that uses artificial intelligence to predict if a patient in the ICU might develop acute kidney injury (sudden kidney damage). It aims to see if the software is cost-effective and could help doctors catch problems earlier.
TaichungAges 20 years+ - NCT07651514Recruiting
Magnesium and Melatonin for Better Sleep and Leg Cramps
This study tests whether taking daily magnesium and melatonin supplements can help improve sleep quality and reduce nighttime leg cramps in adults. You'll wear a special ring to track your sleep and use a smartphone app to log your experiences.
Palm Beach Gardens, FloridaAges 40–75 - NCT07649317RecruitingPhase 1
Ketoconazole effects on cortisol rhythms in mild adrenal hormone changes
This study tests whether the drug ketoconazole can safely help regulate daily cortisol patterns in people with mild autonomous cortisol secretion (MACS), a condition where the adrenal glands make too much cortisol. It will compare how patients with MACS and healthy volunteers respond to the medication.
Bethesda, MarylandAges 18–100 - NCT07648693Recruiting
Brain Protection Device During Aortic Valve Replacement
This trial tests a new device called CHORDS that protects your brain during transcatheter aortic valve replacement (TAVR), a minimally invasive procedure to fix a narrow aortic valve. The device works by blocking debris that might travel to your brain during the procedure.
Bengbu, AnhuiAges 18 years+ - NCT07647172Recruiting
Flavonoid Treatment for Hemorrhoids After Minimally Invasive Surgery
This study tests whether a plant-based medicine called MPFF (a purified flavonoid fraction) helps reduce symptoms and improve healing after minimally invasive surgery for hemorrhoids. You would take this medicine before and after your scheduled procedure.
MoscowAges 18 years+ - NCT07654829RecruitingPhase 4
Sebetralstat to prevent swelling before procedures in HAE
This trial tests if sebetralstat can prevent swelling attacks before medical procedures in people with HAE types I or II. You take the medicine short-term before your procedure to see if it helps protect you from an attack.
Colorado Springs, ColoradoAges 12 years+ - NCT07654114RecruitingPhase 2
Testing CTH120 for men with Fragile X syndrome
This trial tests a new medicine called CTH120 to see if it is safe and helpful for adult men with Fragile X syndrome. You may be able to join if you meet certain health and age requirements.
Barcelona, BarcelonaAges 18–45 - NCT06684392Recruiting
Breathing muscle training to help remove tracheostomy tube
This trial tests whether a special breathing exercise program can help people with a tracheostomy (a tube in the throat to help breathing) get the tube removed faster. It is for adults who are awake and can cooperate.
Rancagua, Región del Libertador General Bernardo O’HigginsAges 18 years+ - NCT05396170Recruiting
Blood draws to lower heart rate in blood-thickening disease
This trial studies whether regular blood removal (phlebotomy) can change your heart rate in people with polycythaemia who already need these blood draws regularly. If you qualify, you may be asked to use a smartphone during the study so researchers can track your heart rate changes over time.
Leiden, South HollandAges 18 years+ - NCT06260618Recruiting
Testing a new gel for better healing in ear surgery
This trial tests a special gel applied during common ear surgeries to see if it helps healing and improves hearing. It may be an option for people having surgery to fix a perforated eardrum, repair ear bones, or treat chronic ear infections.
Adelaide, South AustraliaAges 18 years+ - NCT07655011Recruiting
Exercise order in lung rehab for COPD patients
This trial tests if the order of exercises during pulmonary rehabilitation can improve muscle strength in people with COPD. It compares different exercise sequences to find the most effective approach.
ReimsAges 18 years+ - NCT07648654Recruiting
Hall Technique vs. Traditional Crowns for Decayed Baby Molars
This study compares two ways to treat decayed baby molars in children ages 5–8: the Hall Technique (a newer method) and traditional stainless-steel crowns. Researchers will measure which method works better, reduces anxiety, takes less time, and costs less.
CairoAges 5–8 - NCT07649109RecruitingPhase 4
Heart Device Detected Irregular Heartbeats: Treatment Study
This study follows patients who have a heart rhythm device (pacemaker, defibrillator, or resynchronization device) and have experienced brief episodes of fast irregular heartbeats detected by the device. The study compares treatment approaches to understand which helps patients stay healthier and feel better.
TaipeiAges 18 years+ - NCT07646405Recruiting
Electrical stimulation and light resistance training for older adults' muscles
This study tests whether combining electrical muscle stimulation (a gentle electrical current applied to muscles) with light resistance exercises can help adults over 65 build stronger leg muscles and improve their ability to walk and move around.
Lahore, Punjab ProvinceAges 65–85 - NCT07646288Recruiting
Visual Feedback Breathing Training After Lung Cancer Surgery
This study tests whether using visual feedback (like watching a screen) during breathing exercises helps lung cancer patients recover better after surgery to remove part of a lung. The goal is to see if this type of guided breathing practice improves how well your lungs work after the operation.
Ankara, AltındağAges 18–75 - NCT07650318Recruiting
Virtual reality brain training for diabetes patients with memory issues
This trial tests whether virtual reality brain training can help protect thinking and memory in people with type 2 diabetes who have mild memory problems. If you have type 2 diabetes and notice some mental decline, this study may help you find ways to keep your mind sharp.
Nanjing, JiangsuAges 45–80 - NCT07652333Recruiting
Strength training for muscle and mind on obesity medication
This study tests whether strength training can help adults taking new obesity medications (like Wegovy or Ozempic) maintain muscle and improve mental health. You would start the medication after your first study visit.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07650422Recruiting
Virtual Reality to Reduce Anxiety During Cervical Screening
This study tests whether wearing a virtual reality headset during a colposcopy (a procedure to examine the cervix) can help reduce anxiety, stress, and pain. You would be randomly assigned to either use VR or receive standard care during the procedure.
Adana, AdanaAges 18 years+ - NCT07651722Recruiting
Pain control and gut recovery after abdominal surgery
This trial tests a combination of two pain-management approaches—a long-acting numbing medicine injected near nerves and a self-administered opioid—to see if they help your gut function better and control pain after bowel or colon surgery.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT07650058Recruiting
How Fresh Mango Affects Blood Sugar in Breakfast
This study tests whether eating fresh mango instead of sugar in breakfast affects how your body handles blood sugar. Researchers want to understand if mango is a healthier breakfast option for young, generally healthy adults.
Muncie, IndianaAges 18–45
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,377 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.