Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,378 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07661290Recruiting
High-power laser therapy for cervical radiculopathy
This study tests whether high-power laser therapy can help people with cervical radiculopathy (nerve pain from the neck). The laser is applied to the neck to reduce pain and improve function, and the trial will also see if it affects the shape of the discs in the spine.
CairoAges 40–60 - NCT07662837Recruiting
Comparing Tai Chi and Qi Gong for Early Parkinson's
This study compares two gentle mind-body exercises, Tai Chi and Qi Gong, to see which one better helps people with early-stage Parkinson's disease. If you are between 50 and 65 and have stable medication, you may join to find out if these practices can improve your balance, movement, and well-being.
Lahore, Punjab ProvinceAges 50–65 - NCT06398496Recruiting
Exercise, gut health, mood in depression
This trial studies whether a 12-week exercise program can improve gut bacteria, mood, and thinking in people with depression. It may help if you are looking for a non-medication way to support your mental health.
Cork, Cork CountyAges 18–59 - NCT05882903RecruitingPhase 2
Nasal steroid cream after sinus surgery for chronic sinus trouble
This trial studies whether placing a steroid nasal cream inside your sinus area can reduce symptoms in people with chronic rhinosinusitis (CRS) even after sinus surgery. It may help lower ongoing inflammation and symptoms for those who still feel unwell despite usual medical treatments.
Sydney, New South WalesAges 18–80 - NCT05416684Recruiting
PEEK vs titanium skull repair after brain surgery
This is an observation study that compares outcomes after two types of skull repair: PEEK and titanium. It may help doctors understand which option works best and how patients recover, without requiring an experimental treatment plan.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06603831Recruiting
3D digital surgery study for bone and joint procedures
This study tests whether 3D digital planning tools make surgeries for certain bone and joint problems more effective and cost-efficient. If you need a specific type of surgery on your forearm, pelvis, or spine, this trial could help determine if digital surgery improves your recovery.
Sabadell, BarcelonaAges 18–80 - NCT03918408RecruitingPhase 1
Platinum eye drops and light to slow keratoconus
This Phase 1 study tests whether a specific corneal cross-linking system (called PXL-Platinum 330) is safe and effective for people with progressive keratoconus, a condition that makes the cornea thin and bulge. The goal is to slow vision changes and see how well the treatment works in the short term.
Eugene, OregonAges 12–45 - NCT06451562Recruiting
Pain relief methods after scoliosis surgery
This trial compares two ways to manage pain after scoliosis surgery: numbing the area near the spine (regional anesthesia) or giving lidocaine through an IV. The goal is to see which method reduces the need for morphine after surgery.
Be’er Ya‘aqovAges 12–25 - NCT06533137Recruiting
How your mind can influence the placebo effect
This trial studies how your awareness and personal beliefs affect the placebo effect—a real improvement in symptoms from a treatment that has no active medicine. Researchers are looking at healthy people to understand how the mind and body interact, which could help improve future treatments.
MilanAges 18 years+ - NCT06671665Recruiting
Manual therapy for low back pain in women with osteopenia
This study tests if manual therapy (hands-on treatment by a therapist) can reduce low back pain in postmenopausal women who have osteopenia, a condition where bones are weaker than normal but not yet osteoporosis. It aims to help with pain located in the lower back area.
GizaAges 50–60 - NCT06685367Recruiting
AI software for predicting acute kidney injury in ICU
This trial tests software that uses artificial intelligence to predict if a patient in the ICU might develop acute kidney injury (sudden kidney damage). It aims to see if the software is cost-effective and could help doctors catch problems earlier.
TaichungAges 20 years+ - NCT07651514Recruiting
Magnesium and Melatonin for Better Sleep and Leg Cramps
This study tests whether taking daily magnesium and melatonin supplements can help improve sleep quality and reduce nighttime leg cramps in adults. You'll wear a special ring to track your sleep and use a smartphone app to log your experiences.
Palm Beach Gardens, FloridaAges 40–75 - NCT07649317RecruitingPhase 1
Ketoconazole effects on cortisol rhythms in mild adrenal hormone changes
This study tests whether the drug ketoconazole can safely help regulate daily cortisol patterns in people with mild autonomous cortisol secretion (MACS), a condition where the adrenal glands make too much cortisol. It will compare how patients with MACS and healthy volunteers respond to the medication.
Bethesda, MarylandAges 18–100 - NCT07647172Recruiting
Flavonoid Treatment for Hemorrhoids After Minimally Invasive Surgery
This study tests whether a plant-based medicine called MPFF (a purified flavonoid fraction) helps reduce symptoms and improve healing after minimally invasive surgery for hemorrhoids. You would take this medicine before and after your scheduled procedure.
MoscowAges 18 years+ - NCT07648693Recruiting
Brain Protection Device During Aortic Valve Replacement
This trial tests a new device called CHORDS that protects your brain during transcatheter aortic valve replacement (TAVR), a minimally invasive procedure to fix a narrow aortic valve. The device works by blocking debris that might travel to your brain during the procedure.
Bengbu, AnhuiAges 18 years+ - NCT07654829RecruitingPhase 4
Sebetralstat to prevent swelling before procedures in HAE
This trial tests if sebetralstat can prevent swelling attacks before medical procedures in people with HAE types I or II. You take the medicine short-term before your procedure to see if it helps protect you from an attack.
Colorado Springs, ColoradoAges 12 years+ - NCT07654114RecruitingPhase 2
Testing CTH120 for men with Fragile X syndrome
This trial tests a new medicine called CTH120 to see if it is safe and helpful for adult men with Fragile X syndrome. You may be able to join if you meet certain health and age requirements.
Barcelona, BarcelonaAges 18–45 - NCT06684392Recruiting
Breathing muscle training to help remove tracheostomy tube
This trial tests whether a special breathing exercise program can help people with a tracheostomy (a tube in the throat to help breathing) get the tube removed faster. It is for adults who are awake and can cooperate.
Rancagua, Región del Libertador General Bernardo O’HigginsAges 18 years+ - NCT05396170Recruiting
Blood draws to lower heart rate in blood-thickening disease
This trial studies whether regular blood removal (phlebotomy) can change your heart rate in people with polycythaemia who already need these blood draws regularly. If you qualify, you may be asked to use a smartphone during the study so researchers can track your heart rate changes over time.
Leiden, South HollandAges 18 years+ - NCT06260618Recruiting
Testing a new gel for better healing in ear surgery
This trial tests a special gel applied during common ear surgeries to see if it helps healing and improves hearing. It may be an option for people having surgery to fix a perforated eardrum, repair ear bones, or treat chronic ear infections.
Adelaide, South AustraliaAges 18 years+ - NCT07653659Recruiting
Lowering norepinephrine in shock: effects on blood vessel pressure
This study tests whether reducing the dose of a medicine that raises blood pressure (norepinephrine) affects how blood moves through the body in people with distributive shock. If you are on a steady low dose of norepinephrine and have a special heart monitor (PiCCO catheter), this trial may help doctors understand safer ways to wean the medicine.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07649005Recruiting
How Salt and Potassium Affect Blood Vessel Health in Older Adults
This study explores how different amounts of sodium (salt) and potassium in your diet affect your blood vessels and heart health. Researchers will monitor your blood pressure and vascular function over time to understand these dietary effects better.
Tallahassee, FloridaAges 55–75 - NCT07650058Recruiting
How Fresh Mango Affects Blood Sugar in Breakfast
This study tests whether eating fresh mango instead of sugar in breakfast affects how your body handles blood sugar. Researchers want to understand if mango is a healthier breakfast option for young, generally healthy adults.
Muncie, IndianaAges 18–45 - NCT07650591Recruiting
Tapping and vibration to ease needle pain in children
This study tests whether rhythmic tapping and gentle vibration near the skin can help children ages 6–12 feel less pain and fear during blood draws. Researchers want to see if these simple techniques can make the procedure more comfortable.
Antalya, KepezAges 6–12
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,378 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.