Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06874036Recruiting
Bowel prep and colonoscopy safety in heart, kidney, or liver disease
This study tests how well people with chronic heart, kidney, or liver disease tolerate bowel preparation and colonoscopy. It aims to ensure the procedure is safe and effective for you.
Hyderabad, TelanganaAges 18–75 - NCT07304089RecruitingPhase 2
Study of VIM0423 for people with dystonia affecting multiple body areas
This trial tests an investigational medicine called VIM0423 for people with isolated dystonia that affects two or more body areas. The study aims to see if the medicine is safe, tolerable, and effective in reducing dystonia symptoms.
Birmingham, AlabamaAges 18–70 - NCT07303777RecruitingPhase 2
Study of ABP-745 for people with atherosclerosis
This trial tests a new medication called ABP-745 to see if it helps people with atherosclerosis (hardening of the arteries). It is for people who are already taking a cholesterol-lowering medicine and who have had a special heart artery X-ray (coronary angiography).
Beverly Hills, CaliforniaAges 18–75 - NCT07289763RecruitingPhase 2
Study of SHR-2173 for primary membranous nephropathy
This trial tests an investigational drug called SHR-2173 for people with primary membranous nephropathy, a kidney disease that causes protein leakage. The study aims to see if the drug is safe and effective, and it involves periodic injections and monitoring.
Nanjing, JiangsuAges 18–75 - NCT07288320RecruitingPhase 2
Testing NBI-1117568 for bipolar I mania
This trial tests an experimental drug called NBI-1117568 for people with bipolar I disorder who are currently having a manic or mixed episode. The goal is to see if the drug helps calm mania symptoms and is safe.
Little Rock, ArkansasAges 18–65 - NCT07281833RecruitingPhase 3
Testing capivasertib with hormone therapy for advanced breast cancer
This trial tests a new oral drug called capivasertib combined with standard hormone therapy for people with advanced breast cancer that is HR-positive and HER2-negative. It is for those whose cancer has progressed on previous hormone therapy and who have a specific gene change (PIK3CA, AKT1, or PTEN).
AnderlechtAges 18 years+ - NCT07266402RecruitingPhase 3
Study of barzolvolimab for cold hives or skin writing
This trial tests an investigational drug called barzolvolimab for people with cold-induced hives or a condition where scratching causes raised lines (symptomatic dermographism) that aren't well controlled by antihistamines. The study compares the drug to a placebo to see if it reduces itching and hives.
Birmingham, AlabamaAges 18 years+ - NCT07260500RecruitingPhase 2
Growth hormone study for short children born small for gestational age
This trial tests a weekly growth hormone injection called PEG-rhGH to see if it helps short children born small for gestational age grow taller. It may be an option if your child has never taken growth hormone before and meets the height and age requirements.
Wuhan, HubeiAges 3 years+ - NCT07249788RecruitingPhase 4
Resmetirom for MASH: A study on safety and effectiveness
This trial tests if resmetirom can help people with MASH, a type of fatty liver disease linked to metabolic issues like diabetes or obesity. It looks at how safe and effective the drug is over time.
Rawalpindi, Punjab ProvinceAges 18–75 - NCT07249463RecruitingPhase 2
Testing a new drug for cryptosporidium infection in healthy adults
This trial tests a new drug, EDI048, to see how well it works and how safe it is for treating cryptosporidium infection. It is for healthy volunteers who will be intentionally exposed to the infection under controlled conditions.
Baltimore, MarylandAges 18–50 - NCT07221734RecruitingPhase 3
Testing MB11 versus Opdivo for advanced melanoma
This trial compares a new drug, MB11, to the standard treatment Opdivo for people with advanced melanoma that hasn't been treated yet. The goal is to see if MB11 works just as well.
FunchalAges 18 years+ - NCT07229950RecruitingPhase 2
Experimental tablet for moderate to severe Ulcerative Colitis
This trial tests an experimental tablet, HRS-7085, for people with moderate to severe Ulcerative Colitis who haven't gotten enough help from standard treatments. The goal is to see if the drug can reduce inflammation and improve symptoms.
Chengdu, SichuanAges 18–75 - NCT03716089Recruiting
Laparoscopic surgery for stomach GIST by tumor site
This trial studies whether doing laparoscopic surgery for stomach GISTs (gastrointestinal stromal tumors) works and is safe when the tumor is in a “favorable” versus “unfavorable” location. You might be eligible if your tumor is confirmed as GIST and doctors expect to remove it completely using keyhole surgery.
Fuzhou, FujianAges 18–75 - NCT07217067RecruitingPhase 2
Study of PKN605 for people with atrial fibrillation
This trial tests a new medicine called PKN605 for people with atrial fibrillation (irregular heartbeat). The goal is to see if it can safely help control heart rhythm. You will need to have had at least two AF episodes recently and meet other heart health criteria.
Tupelo, MississippiAges 18 years+ - NCT07215390RecruitingPhase 2
Study of APL-3007 plus Syfovre for geographic atrophy
This trial tests whether a new drug called APL-3007, when added to your current Syfovre treatment, can slow the progression of geographic atrophy (an advanced form of dry age-related macular degeneration). It's for people who have already been on Syfovre for at least 6 months.
Gilbert, ArizonaAges 60 years+ - NCT07217171RecruitingPhase 1
Study of EVOLVE104 for advanced bladder and squamous cell cancers
This trial tests an experimental drug called EVOLVE104 for people with advanced bladder cancer or certain types of squamous cell cancers. It aims to see if the drug is safe and if it can help shrink tumors.
Duarte, CaliforniaAges 18 years+ - NCT07215702RecruitingPhase 2
Testing a drug for kidney injury from sepsis in the ICU
This trial tests if a new drug, AZD4144, can help people with sepsis-related acute kidney injury in the ICU. It aims to see if the drug can improve kidney recovery and reduce complications.
Phoenix, ArizonaAges 18–80 - NCT06912061Recruiting
New needle technique for Achilles tendon lengthening in kids
This study tests a new needle-based method to lengthen a tight Achilles tendon in children, which can help with toe walking or foot pain. The goal is to see if it works well and is safe.
DrammenAges 5–16 - NCT07209033Recruiting
Testing FlexiOss for bone repair in leg and foot fractures
This trial tests a new material called FlexiOss to help heal broken bones in the leg or foot. It aims to see if the material is safe and effective for bone regeneration.
KrakowAges 18–75 - NCT07204275RecruitingPhase 2/Phase 3
Testing povetacicept for primary membranous nephropathy
This study tests an investigational drug called povetacicept for people with primary membranous nephropathy, a kidney disease. Researchers want to see if it is safe and helps reduce protein in the urine.
Montgomery, AlabamaAges 18–75 - NCT07208058RecruitingPhase 3
Testing plonmarlimab for blood cell overactivation in people with rheumatic disease
This trial tests a new drug called plonmarlimab for people with a rheumatic (joint or immune) disease who also have a dangerous overreaction of their immune system called HLH (or MAS). The goal is to see if the drug can help when high-dose steroids have not worked or are not an option.
Beijing, Beijing MunicipalityAges 16–80 - NCT06926179Recruiting
Immunotherapy before surgery or radiation for lung cancer
This trial tests using immunotherapy before surgery or radiation for non-small cell lung cancer. It looks at how safe and effective this approach is and how it affects survival.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07203001RecruitingPhase 2
MAS825 for Still's disease in children and adults
This trial tests a new drug called MAS825 for people with Still's disease that is still active despite other treatments. It aims to see if the drug can reduce symptoms like fever, rash, joint pain, or a serious complication called macrophage activation syndrome.
Cincinnati, OhioAges 1 year+ - NCT07198139RecruitingPhase 1/Phase 2
Testing a new norovirus treatment in healthy adults
This trial tests an investigational medicine called CDI-988 to see if it can prevent or treat norovirus infection. Healthy adults will be intentionally exposed to a mild norovirus strain to see how the medicine works.
Decatur, GeorgiaAges 18–49
Hear when a new Efficacy and Safety trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.