Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,799 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06394830RecruitingPhase 2
Testing VNX001 for bladder pain syndrome
This study tests a new treatment (VNX001) for people with interstitial cystitis or bladder pain syndrome (IC/BPS). You must have already taken part in an earlier study of this drug to join. The goal is to see if it safely reduces bladder pain.
Tucson, ArizonaAges 18 years+ - NCT06403943RecruitingPhase 4
Chinese herbs with standard TB treatment for lung health
This trial tests if adding a Chinese herbal formula (BaiDiZiYin ShenQiYiFei) to standard tuberculosis drugs helps improve symptoms like shortness of breath, fatigue, and coughing. It may be helpful for people diagnosed with pulmonary TB who also have signs of Qi and Yin deficiency (a traditional Chinese medicine pattern).
Beijing, Beijing MunicipalityAges 18–65 - NCT06439771RecruitingPhase 2
Testing YL202 for advanced breast cancer
This trial tests a new drug called YL202 for people with advanced breast cancer. It is for those who have already tried certain targeted treatments (HER2 or TROP2 antibody-drug conjugates) and they stopped working. The goal is to see if YL202 can help shrink tumors or slow cancer growth.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06463665RecruitingPhase 2
Virus therapy with chemo and immunotherapy for advanced lung cancer
This trial tests a new treatment that uses a virus to attack cancer cells, combined with standard chemotherapy and an immunotherapy drug, for people with advanced non-small cell lung cancer that has gotten worse after initial treatment. The goal is to see if this combination works better than a different chemotherapy drug alone.
Bullhead City, ArizonaAges 18 years+ - NCT07693036RecruitingPhase 1/Phase 2
Exosomes from stem cells for type 2 diabetes
This trial tests if a type of stem cell product (exosomes) can safely and effectively help people with type 2 diabetes. Researchers will give infusions to see if it improves blood sugar control and pancreatic function.
BeijingAges 18–65 - NCT07013747RecruitingPhase 1/Phase 2
Acne mRNA vaccine for mild acne
This trial tests an mRNA vaccine designed to treat mild facial acne. It aims to see if the vaccine is safe and effective at reducing acne lesions.
Encino, CaliforniaAges 18–45 - NCT06507150Recruiting
AI-assisted migraine education for newly diagnosed patients
This study tests a new AI-powered learning tool to help people who were just diagnosed with migraine understand their condition better. You'll use the tool on your own device, and researchers will see if it's helpful and easy to use.
LuganoAges 18–65 - NCT06517862RecruitingPhase 4
Extra medicines with light therapy for newborn jaundice
This trial tests if giving a zinc or bile acid medicine alongside light therapy helps break down jaundice faster in newborns. It could shorten treatment time for babies who need phototherapy in their first week of life.
Cairo, Cairo GovernorateAges 1 day–1 month - NCT06524830RecruitingPhase 2
Testing VLS-01 film for treatment-resistant depression
This trial tests an experimental film placed inside the cheek (VLS-01) against a placebo to see if it helps people whose depression hasn't improved with standard antidepressants. If you have tried at least two antidepressants without success, this study may be an option for you.
Tucson, ArizonaAges 18–65 - NCT07459309Recruiting
Combination treatment for liver cancer for people who can't have surgery
This trial tests a new combination treatment that uses heat (ablation) and other therapies to destroy liver tumors. It's for people who cannot have surgery or choose not to, and whose tumor is a specific size.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06635798RecruitingPhase 3
Testing a medicine to prevent tetanus after dirty wounds
This trial tests a new medicine called GR2001 to help prevent tetanus after a dirty wound. It is for people who have not had many tetanus shots before and need extra protection.
Hefei, AnhuiAges 18 years+ - NCT06671548RecruitingPhase 3
Study of relugolix for heavy periods from uterine fibroids
This trial tests if relugolix can reduce heavy menstrual bleeding caused by uterine fibroids. It may be an option for women who want to avoid surgery.
BeijingAges 18 years+ - NCT06697314Recruiting
Clot removal for acute pulmonary embolism with heart strain
This study tests a new device (AlphaVac) that removes blood clots from the lungs using a thin tube inserted through a vein. It may be an option for people with acute pulmonary embolism who have signs of heart strain or low blood pressure.
PoznanAges 18 years+ - NCT06699849RecruitingPhase 2
CSL889 for sickle cell pain crisis
This trial tests a new medicine, CSL889, for people with sickle cell disease who are currently having a pain crisis (vaso-occlusive crisis). The goal is to see if it safely helps reduce the pain and speed recovery.
Oakland, CaliforniaAges 12 years+ - NCT06700096RecruitingPhase 3
Testing a new drug for adults with severe hemophilia B
This trial tests a single dose of ANB-002, an experimental therapy for hemophilia B. It aims to see if the drug is safe and effective for people with severe hemophilia B who have been treated with factor IX before and do not have inhibitors.
ChelyabinskAges 18 years+ - NCT06704269RecruitingPhase 1/Phase 2
YTB323 for treatment-resistant generalized myasthenia gravis
This trial tests a new CAR-T cell therapy (YTB323) for people with generalized myasthenia gravis that hasn't been well-controlled by standard treatments. The goal is to see if it can safely improve symptoms and change how the immune system attacks the nerves.
Orange, CaliforniaAges 18–65 - NCT05091424RecruitingPhase 1
Mosunetuzumab with or without venetoclax for CLL
This Phase 1 study tests whether mosunetuzumab alone or with venetoclax is safe and effective for people with chronic lymphocytic leukemia (CLL) that came back or did not respond to prior treatment. It may help by controlling the CLL immune system response while also studying dosing and side effects.
Rochester, MinnesotaAges 18 years+ - NCT07277660RecruitingPhase 2
Study of galvokimig for adults with moderate-to-severe eczema
This trial tests whether a new medication, galvokimig, can help adults with moderate-to-severe atopic dermatitis (eczema) that hasn't improved enough with creams or ointments. The study will measure how well the drug works, its safety, and how it behaves in your body.
Oceanside, CaliforniaAges 18 years+ - NCT06915025RecruitingPhase 3
Study of a new drug for advanced ovarian cancer
This trial tests a new drug called IMNN-001 combined with standard chemotherapy for women with advanced ovarian, fallopian tube, or peritoneal cancer. The goal is to see if adding this drug can improve safety and effectiveness.
Orlando, FloridaAges 18 years+ - NCT06709339RecruitingPhase 4
Study of faricimab for Caucasian patients with polypoidal choroidal vasculopathy
This trial tests a drug called faricimab for a type of wet age-related macular degeneration called polypoidal choroidal vasculopathy (PCV). It aims to see if the drug is safe, works well, and how long the effects last in patients who have not been treated before.
MilanAges 50–90 - NCT06727604RecruitingPhase 2
Study of IMVT-1402 for Graves' disease not controlled by medication
This trial tests a new drug called IMVT-1402 for adults with Graves' disease whose thyroid is still overactive despite taking antithyroid medication. The goal is to see if the drug can safely help control thyroid hormone levels.
Phoenix, ArizonaAges 18–75 - NCT06734832RecruitingPhase 3
Vaccine trial for hand, foot, and mouth disease
This trial tests a new two-in-one vaccine to protect children against hand, foot, and mouth disease caused by two common viruses (EV71 and CA16). It is for healthy kids ages 6 months to 5 years and will check if the vaccine is safe and works well.
Hefei, AnhuiAges 6 months–5.9 years - NCT06782490RecruitingPhase 2
Testing a new drug for MS muscle stiffness
This study tests an investigational drug (BMS-986368) to see if it helps reduce muscle stiffness and spasms caused by multiple sclerosis. It may be an option if you have had spasticity for at least 6 months and are not currently using other treatments that cannot be paused.
Birmingham, AlabamaAges 18–70 - NCT06808984RecruitingPhase 2
Testing a new drug for agitation in Alzheimer's disease
This trial tests an investigational drug called BMS-986368 to see if it can safely reduce agitation in people with Alzheimer's disease. You may be able to join if you have Alzheimer's with confirmed biomarkers and experience agitation that has been going on for at least 4 weeks.
Homewood, AlabamaAges 55–90
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,799 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.