Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06875193RecruitingPhase 4
Comparing dapagliflozin vs pioglitazone for type 2 diabetes
This study is testing two different diabetes pills—dapagliflozin or pioglitazone—in people with type 2 diabetes. The goal is to see which one works better when added to your current metformin and DPP-4 inhibitor. You may qualify if your blood sugar is not well controlled with your current medications.
SeoulAges 19 years+ - NCT07295275Recruiting
Fluorescence-guided surgery for liver cancer
This trial tests a new way to remove liver cancer during surgery. A special dye called ICG is injected into the artery leading to the liver, which makes the tumor glow under a special camera, helping the surgeon remove just the right area. This study checks if this technique is both safe and effective for people with a common type of liver cancer (hepatocellular carcinoma).
Beijing, Beijing MunicipalityAges 18–80 - NCT07292168RecruitingPhase 1/Phase 2
Study of a new antibody for advanced tumors with FGFR1 protein
This trial tests an experimental antibody, OM-RCA-01, in people with advanced solid tumors that have high levels of a protein called FGFR1. It aims to see if the drug is safe and effective for those who have already tried other treatments.
Kazan'Ages 18 years+ - NCT07290010RecruitingPhase 2
Iparomlimab plus chemotherapy for advanced esophageal cancer
This trial tests a combination of two immunotherapy drugs (Iparomlimab and Tuvonralimab) with chemotherapy as a first treatment for advanced esophageal squamous cell carcinoma. It aims to see if this combination is safe and effective for people whose cancer cannot be removed by surgery or has spread.
Shijiazhuang, HebeiAges 18 years+ - NCT07287943Recruiting
Medtronic pump study for diabetes and gastroparesis
This study tests whether the Medtronic 780G insulin pump helps people with type 1 diabetes and gastroparesis (slowed stomach emptying) control their blood sugar better than their usual care. It requires continuous glucose monitoring and certain blood sugar levels.
Indianapolis, IndianaAges 18 years+ - NCT07287982RecruitingPhase 2
ARGX-119 for children with SMA who can walk
This study tests a new medicine called ARGX-119 in children with SMA. It is given through an IV and aims to help kids who can already walk get stronger and stay healthy.
Little Rock, ArkansasAges 5–17 - NCT07288177RecruitingPhase 2
A study of Rina-S for people with non-small cell lung cancer
This trial tests a new drug called Rina-S for people with non-small cell lung cancer that has spread or can't be removed by surgery. It aims to see if the drug can shrink tumors and how safe it is.
Fountain Valley, CaliforniaAges 18 years+ - NCT07288567RecruitingPhase 3
KarXT for teens with schizophrenia
This trial tests if a new medicine, KarXT, can safely and effectively treat schizophrenia in adolescents. It may help teenagers who have active symptoms like hallucinations or disorganized thinking.
Anaheim, CaliforniaAges 13–17 - NCT06757244RecruitingPhase 2
Dovipa: Immunotherapy and vitamin D with chemo for advanced pancreatic cancer
This trial tests whether combining the immunotherapy dostarlimab with vitamin D3 and standard chemotherapy (mFOLFIRINOX) can help people with stage IV pancreatic cancer. It aims to see if this new approach is safe and effective.
MarseilleAges 18–75 - NCT06231381RecruitingPhase 2
HB0034 for severe pustular psoriasis flare
This study tests an experimental drug called HB0034 for people with a sudden, severe flare of generalized pustular psoriasis (GPP). It aims to see if the drug can safely clear the pustules and improve symptoms.
BeijingAges 18–75 - NCT07284849RecruitingPhase 3
Testing a new drug combo for advanced colorectal cancer
This trial tests whether adding an experimental drug (INCA33890) to standard chemotherapy and bevacizumab helps people with a certain type of advanced colorectal cancer. It is for those whose cancer has spread and has not been treated yet with systemic therapy.
Mobile, AlabamaAges 18 years+ - NCT07284472RecruitingPhase 2/Phase 3
Testing drugs for agitation in Alzheimer's disease
This trial tests two new drugs (EXV-802 and EXV-801) to see if they can safely reduce moderate to severe agitation in people with Alzheimer's dementia. If you or a loved one has Alzheimer's and has been experiencing significant agitation for at least two weeks, this study may be an option.
Murrieta, CaliforniaAges 55–90 - NCT07285005RecruitingPhase 3
Study of an oral drug for venous, lymphatic, and certain overgrowth syndromes
This trial tests whether the study drug KP-001 can help reduce symptoms like pain, fatigue, or bleeding caused by certain vascular malformations (abnormal blood vessel growths) that can't be surgically removed or haven't responded to other treatments. It's for people age 2 and older with specific conditions such as common venous malformations, lymphatic malformations, or KTS/CLOVES syndrome.
Charleston, South CarolinaAges 2 years+ - NCT07286032RecruitingPhase 3
Study of a pill to raise low platelets after chemo
This study tests an investigational pill (hetrombopag) to see if it can safely raise platelet counts in people with solid tumors whose platelets drop after chemotherapy. If you are receiving platinum- or gemcitabine-based chemo and have low platelets due to chemo, this trial may be an option.
Long Beach, CaliforniaAges 18 years+ - NCT07282210RecruitingPhase 2
New medicine for sickle cell hemolysis
This trial tests a new medicine (SIL-8301) to help control red blood cell breakdown (hemolysis) in people with sickle cell disease. It is for those who are already taking hydroxyurea and have had few pain crises but still have complications from hemolysis.
Toronto, OntarioAges 16–35 - NCT07283796RecruitingPhase 1
Study of HSK47977 for relapsed or refractory non-Hodgkin lymphoma
This trial tests an experimental drug (HSK47977) to see how it works in people with non-Hodgkin lymphoma that has come back or not responded to treatment. The goal is to understand how the drug is processed by the body, its safety, and whether it can help shrink tumors.
TianjinAges 18 years+ - NCT07279493RecruitingPhase 2
Testing KPCXM18 injection for acute ischemic stroke within 12 hours
This trial tests an investigational injection called KPCXM18 for people having an acute ischemic stroke. It is given within 12 hours of symptom onset, in addition to standard clot-dissolving treatment, to see if it improves recovery and safety.
Beijing, Beijing MunicipalityAges 18–80 - NCT07279194RecruitingPhase 3
Study of HDM1005 for weight loss in Chinese adults without diabetes
This trial tests a new medication, HDM1005, to help people with obesity or overweight who do not have diabetes lose weight. It is for Chinese adults who have a high body mass index (BMI) or a BMI above 24 with weight-related health problems like high blood pressure or fatty liver.
ShanghaiAges 18 years+ - NCT07282028RecruitingPhase 2/Phase 3
Spectacle hearing aid study for adults with mild to moderate hearing loss
This study tests a new hearing aid built into glasses for people who have mild to moderate hearing trouble, especially in noisy places. It aims to see if the glasses help you hear better without needing a traditional hearing aid.
Tel AvivAges 18 years+ - NCT07285655RecruitingPhase 3
Study of L606 for lung disease with high blood pressure in the lungs
This trial tests a new treatment called L606 for people who have both a type of lung disease (ILD) and high blood pressure in the lungs (PH). The goal is to see if it is safe and helps with exercise and breathing.
Phoenix, ArizonaAges 18–80 - NCT07284602RecruitingPhase 3
Comparing a new drug to pirfenidone for lung scarring
This trial tests a new medicine, LYT-100 (deupirfenidone), against the standard drug pirfenidone for people with idiopathic pulmonary fibrosis (IPF). It aims to see if the new drug works better or has fewer side effects.
Palm Spring, CaliforniaAges 40 years+ - NCT07282743RecruitingPhase 2
Study of GL0034 for overweight or obese adults with type 2 diabetes
This trial tests a new medication, GL0034, to see if it helps with weight loss and blood sugar control in people with type 2 diabetes who are overweight. Participants must already be taking metformin and not using other diabetes drugs.
Little Rock, ArkansasAges 18 years+ - NCT06853743RecruitingPhase 2
Study of nicotinamide riboside for Huntington's disease
This trial tests if a vitamin B3-like supplement, nicotinamide riboside, can help people with early to mid-stage Huntington's disease. You will be randomly assigned to take the supplement or a placebo to see if it slows the disease.
OsloAges 18–80 - NCT07286747RecruitingPhase 2
Nicotinic Acid for Reversing Prediabetes
This trial tests whether a controlled-release form of nicotinic acid (a type of vitamin B3) can help people with prediabetes get their blood sugar back to normal. It also looks at how the treatment affects liver health.
BerlinAges 18–79
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.