Clinical trials
Encephalopathy clinical trials
Below are recruiting encephalopathy clinical trials, each written for real people, not researchers. We’re tracking 112 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07363603RecruitingPhase 1/Phase 2
Tianasen for GNAO1-related epilepsy and movement disorders
This trial tests a new drug called Tianasen for children with a specific GNAO1 gene change who have seizures and movement problems that haven't improved with standard treatments. The drug is given via a lumbar puncture (spinal tap) and aims to reduce symptoms.
MoscowAges 1–14 - NCT03535142Recruiting
Fatty liver in people considering bariatric surgery
This study looks at how fatty liver disease may predict future liver health in people with severe weight gain. It compares people who are planning bariatric (weight-loss) surgery with similar people who are not, to better understand who may be at higher risk.
EsbjergAges 18 years+ - NCT07302503Recruiting
MRI study of brain changes in footballers
This study uses a special type of MRI scan to look for tiny changes in the brain's wiring that can happen after head impacts. It compares professional footballers to people who haven't played sports with head impacts, to see if these changes show up on the scan.
StrasbourgAges 32–60 - NCT07275021Recruiting
Brain Injury & Vision Screening in Newborns
This study looks for early signs of vision problems in babies who had brain injuries around the time of birth. It aims to help doctors better identify and predict these issues.
Boston, MassachusettsAges 7 months–10 months - NCT05848271Recruiting
Natural history study for people with HPDL gene changes
This study follows people who have an HPDL gene change to better understand how symptoms and health progress over time. It may help clinicians learn more about the condition and plan future treatments.
San Diego, CaliforniaAges Any age - NCT06808074RecruitingPhase 4
Inhaled amikacin to prevent pneumonia in cirrhosis patients on ventilators
This trial tests whether inhaling an antibiotic called amikacin can prevent ventilator-associated pneumonia in patients with severe liver disease (cirrhosis) who are on a breathing machine. If you or your loved one is in the ICU with liver issues and needs a ventilator, this study may help reduce the risk of a serious lung infection.
Hyderabad, TelanganaAges 18 years+ - NCT07190560Recruiting
Study of a treatment for newborns exposed to chikungunya
This trial tests a new treatment (PC-CHIK-V) for newborns whose mothers had chikungunya around the time of birth. The goal is to see if the treatment can prevent or reduce the infection in babies. Babies who are not treated will also be followed for comparison.
Saint-PierreAges birth–2 days - NCT06958341Recruiting
Brain and nerve disease registry with optional fluid collection
This study collects extra fluid from a spinal tap to learn more about brain and nerve diseases. It may help find better treatments in the future.
Berlin, State of BerlinAges Any age - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT04802707RecruitingPhase 2
Study drug for mitochondrial depletion disorder due to gene changes
This Phase 2 trial tests a treatment made from deoxynucleosides to help people with mitochondrial depletion disorder caused by certain gene changes. If you match the genetic diagnosis, the study may see whether the treatment improves symptoms or disease markers.
Montreal, QuebecAges 1 month–60 years - NCT06938542Enrolling by invitation
Palliative care needs for kids with rare diseases
This study asks children with rare diseases and their families about what kind of palliative care (comfort and support) they need. It aims to understand how to better help families through their child's illness.
Washington D.C., District of ColumbiaAges 1–99 - NCT06891716RecruitingEarly Phase 1
PET scan for TDP-43 proteinopathies
This study tests a new PET scan dye that may help see TDP-43 protein buildup in the brain, which is linked to certain dementias and ALS. It aims to improve diagnosis and tracking of these conditions.
AmsterdamAges 40–70 - NCT06860828Enrolling by invitation
Football players and brain health study: DIAGNOSE CTE
This study looks at brain changes in former college and professional football players, people with memory problems, and healthy controls. It aims to learn more about chronic traumatic encephalopathy (CTE) and Alzheimer's disease.
Phoenix, ArizonaAges 50 years+ - NCT06857539Recruiting
Assessing thinking and movement in high-risk infants
This study looks at how high-risk infants (especially those born early or with brain concerns) develop their thinking and movement skills over time, comparing them to healthy babies. The goal is to better understand and support their development.
CorkAges birth–4 months - NCT02664831Recruiting
Study of inflammation after cardiac arrest in ICU patients
This trial looks at how the body’s inflammation response behaves after someone has a cardiac arrest and was treated in the ICU. It may help doctors understand which patients could benefit from treatments that target harmful inflammation after resuscitation.
Portland, MaineAges 18 years+ - NCT06788262Recruiting
Brain health study for female pro soccer players
This study looks at how heading the ball and minor head impacts might affect the brain and thinking skills in female professional soccer players, compared to tennis players. It aims to help understand any long-term effects of playing soccer.
StrasbourgAges 32–65 - NCT04903015Recruiting
Study brain effects in retiring pro soccer players
This study looks at how years of playing professional soccer may affect the brain and thinking, using MRI (brain scans) and comparisons to people who had little head-impact sports exposure. You might join if you are a retiring Ligue 1 or Ligue 2 player and meet the injury and health criteria.
StrasbourgAges 32–55 - NCT06643598Recruiting
Virtual and lived-experience support for newborns with brain challenges
This study tests whether a program that combines virtual support and a peer who has been through it can help parents of newborns with certain brain conditions. It is designed for families living in rural areas and aims to improve children's recovery.
Madison, WisconsinAges Up to 5 years - NCT06625112Recruiting
STXBP1 disorder clinical trial readiness study
This study is for people with a confirmed STXBP1 genetic change to help prepare for future clinical trials. It collects information about the condition to better understand it.
AntwerpAges Any age - NCT06619106Recruiting
Screening tool for minimal hepatic encephalopathy
This study tests a new cognitive tool to quickly and reliably detect minimal hepatic encephalopathy, a subtle brain change that can occur in people with liver disease. If you have a liver condition like fibrosis or cirrhosis and are already scheduled for a full evaluation (neuropsychological tests, MRI, EEG, and blood ammonia), this tool could help simplify future screening.
ParisAges 18–70 - NCT06555965Recruiting
STXBP1 and SYNGAP1 natural history study
This study follows people with STXBP1 or SYNGAP1 gene changes over time to learn more about how these conditions affect the body and mind. It does not test a treatment but helps researchers understand the natural course of the disorder.
Palo Alto, CaliforniaAges Any age - NCT06429007Enrolling by invitationPhase 1
Metformin for infants after brain injury from HIE
This trial tests whether metformin, a common diabetes medicine, can help heal brain injury in infants who had HIE (lack of oxygen at birth) and were treated with cooling. It aims to see if the drug is safe and possible to give to babies between 3 and 6 months old.
Boston, MassachusettsAges 3 months–6 months - NCT06368648Recruiting
Study of a new forehead sensor for brain pressure monitoring
This study tests a new sensor that measures brain pressure from outside the head. It is for people who are already in the hospital getting their brain pressure and blood pressure monitored continuously.
Phoenix, ArizonaAges 18 years+ - NCT03267615Recruiting
Study in advanced liver scarring using pressure and stiffness tests
This study looks at people over 18 who have advanced, long-term liver scarring. It uses specialized measurements of liver stiffness and pressure to confirm eligibility and may help doctors better understand this condition.
ViennaAges 18–100
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Common questions
- Are there clinical trials for encephalopathy?
- Yes. Clin2 currently lists 112 recruiting encephalopathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a encephalopathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a encephalopathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.