Clinical trials
Encephalopathy clinical trials
Below are recruiting encephalopathy clinical trials, each written for real people, not researchers. We’re tracking 111 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07264166Enrolling by invitation
Gene therapy trial for cerebral palsy and HIE
This trial tests a gene therapy given as a nose spray for people with cerebral palsy or HIE. It aims to see if the treatment is safe and helps improve movement over two years.
Monterrey, Nuevo LeónAges 2–65 - NCT06747260RecruitingEarly Phase 1
Breast milk through the nose for HIE
This trial tests whether giving fresh breast milk through the nose is safe and possible for newborns with HIE (a brain injury from oxygen loss at birth) who are already receiving cooling therapy. It may help protect the brain and reduce injury.
BudapestAges Up to 2 days - NCT07683936RecruitingEarly Phase 1
Fecal transplant for brain issues after liver procedure
This trial tests if transferring healthy bacteria into your gut (fecal microbiota transplant) can help people who still get confusion episodes (hepatic encephalopathy) even after a TIPS procedure and while on standard medications like lactulose and rifaximin.
Xi'anAges 18–75 - NCT06746532RecruitingEarly Phase 1
Breast milk nose drops for brain injury in newborns
This trial tests whether giving fresh breast milk as nose drops can help newborns with brain injury from lack of oxygen. It aims to see if this simple treatment can improve brain recovery.
BudapestAges Up to 2 days - NCT07165938Recruiting
Genetics of newborn brain injury study
This study looks for genes that may cause or increase the risk of brain injury in newborns. It may help researchers understand why some babies develop encephalopathy and could lead to better treatments in the future.
Boston, MassachusettsAges Any age - NCT06762795Recruiting
Gene study for newborns with HIE on cooling therapy
This study uses whole genome sequencing to look at the genes of newborns with HIE (brain injury from lack of oxygen) who are receiving cooling treatment. The goal is to learn more about how genes may affect recovery and outcomes.
Houston, TexasAges birth–1 year - NCT05971446Recruiting
Healthy Little Eyes study for newborn vision and brain health
This study looks at eye and vision outcomes in babies who have had lack of oxygen around birth (HIE) and also compares them with healthy “well babies.” It may help doctors better understand how HIE affects the eyes and what to watch for over time.
Madison, WisconsinAges Up to 3 years - NCT05514340RecruitingPhase 2
Test drug for brain injury after low oxygen at birth
This Phase 2 study tests whether sovateltide can improve safety and outcomes for babies whose brains may have been injured by low oxygen around birth. It focuses on babies who show signs of moderate to severe injury soon after delivery, and who receive standard supportive care.
Mangalore, KarnatakaAges Any age - NCT03470467Recruiting
ICU study of a reversible brain swelling condition
This trial looks at Posterior Reversible Encephalopathy Syndrome (PRES) in adults in the ICU. It may help doctors better understand and manage a condition that can cause seizures, confusion, headaches, and vision problems, and that typically shows specific changes on brain scans.
Le ChesnayAges 18 years+ - NCT04161053RecruitingPhase 3
Nitazoxanide to prevent repeat liver brain episodes
This Phase 3 trial tests whether nitazoxanide can help stop hepatic encephalopathy (a “liver-to-brain” confusion problem) from coming back. It’s for adults with cirrhosis who have had at least one past episode, aiming to improve safety and prevent recurrence.
TantaAges 20–65 - NCT05767476Recruiting
Testing cooling treatment after lack of oxygen at birth
This trial studies outcomes in newborns who had breathing problems from low oxygen before or during birth and were treated with a cooling therapy (therapeutic hypothermia). It may help doctors understand which babies benefit most and what recovery looks like over time.
RomeAges 10 minutes–6 hours - NCT04230447Recruiting
Study of brain confusion in sepsis patients
This study builds a group of adults with sepsis who develop sudden brain problems, like delirium or coma. It aims to better understand how often this happens and how it may be recognized in hospital, which could help future care.
Beijing, Beijing MunicipalityAges 18–89 - NCT05395195RecruitingPhase 3
Erythropoietin for newborn brain injury in low-resource settings
This Phase 3 trial studies whether erythropoietin (a medicine related to red-blood-cell growth) can improve outcomes for newborns with moderate to severe brain injury after birth. The study focuses on babies born in low- and middle-income countries and aims to reduce harm from this early brain condition.
DhakaAges 1 hour–6 hours - NCT07799948Recruiting
Stent adjustment for repeated confusion after liver shunt
This study tests a procedure to narrow a stent in the liver to reduce episodes of confusion caused by toxins reaching the brain. It may help people who still have frequent confusion despite standard treatments.
Xi'an, ShaanxiAges 18 years+ - NCT02881970RecruitingPhase 1/Phase 2
Cord blood stem cell treatment for newborn brain injury
This early-phase study tests whether using a baby’s own cord blood stem cells is safe and feasible for newborns with brain injury from lack of oxygen around birth. It may help researchers find new ways to treat hypoxic-ischemic encephalopathy (brain injury due to oxygen deprivation) in addition to standard care like cooling.
MarseilleAges 1 day–3 days - NCT07770035Enrolling by invitation
School-age outcomes after newborn brain injury
This study looks at how children who had a brain injury around birth (called hypoxic-ischaemic encephalopathy, or HIE) are doing in school and daily life, compared to children without that history. It aims to understand the long-term effects and support needs.
Cork, CorkAges 5–12 - NCT07628829Recruiting
Video AI to Monitor Newborn Brain Health
This study uses artificial intelligence to watch and analyze videos of newborns in the hospital nursery or NICU to help doctors spot neurological problems early. The goal is to see if this video AI tool can safely and accurately help care for newborns during their hospital stay.
New York, New YorkAges Any age - NCT07555652Recruiting
Cooling treatment for newborns with birth-related brain injury
This trial studies whether cooling a newborn's body after a difficult birth helps prevent brain damage. Researchers will track babies treated with this cooling therapy and use brain imaging to see how well it works.
Ha Nội, HanoiAges birth–6 hours - NCT07527104Recruiting
Bone marrow cells and rehabilitation for cerebral palsy in young children
This trial tests whether transplanting cells from a child's own bone marrow, combined with rehabilitation therapy, can improve movement and function in young children with cerebral palsy caused by birth-related brain injury or bleeding. The goal is to see if this approach helps children move better and become more independent.
Hanoi, HanoiAges 6 months–18 years - NCT07493096Recruiting
Intensive therapy program for children with brain-based conditions
This trial tests an intensive therapy program designed to help children with brain-based conditions like cerebral palsy or autism improve their skills in movement, thinking, and daily activities. The program runs for 2 weeks with daily sessions, and researchers will check for changes in your child's abilities.
The Woodlands, TexasAges 4–12 - NCT04073290RecruitingPhase 4
Rifaximin and lactulose to prevent confusion after TIPS
This trial studies whether taking rifaximin plus lactulose can prevent a brain problem called hepatic encephalopathy (confusion) after TIPS, a procedure to reduce pressure in the liver. It may help people who are having TIPS planned and are at risk of this complication.
LeuvenAges 18–80 - NCT07393620Recruiting
Predicting brain outcomes in newborns with mild oxygen loss
This study uses brain monitoring and oxygen measurements in newborns who had a mild lack of oxygen at birth to see if these tests can predict how the baby will develop. The goal is to find early signs that might help guide care.
BursaAges birth–6 hours - NCT06855901Recruiting
Home EEG monitoring for rare epilepsy
This study tests using a small, home-based EEG device to monitor brain activity over several weeks in people with hard-to-control seizures, rare epilepsies, or developmental and epileptic encephalopathies. The goal is to see if this method can better track seizures and improve care.
Roma, ItalyAges 12 years+ - NCT07349654Recruiting
New stent method to reduce brain fog after TIPS procedure
This trial tests a modified stent placement technique during TIPS (a procedure to lower blood pressure in the liver) to see if it helps prevent confusion and memory problems that can happen afterward.
Chongqing, Chongqing MunicipalityAges 18–75
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Common questions
- Are there clinical trials for encephalopathy?
- Yes. Clin2 currently lists 111 recruiting encephalopathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a encephalopathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a encephalopathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.