Clinical trials
Neonatal Encephalopathy clinical trials
Below are recruiting neonatal encephalopathy clinical trials, each written for real people, not researchers. We’re tracking 30 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02544100Recruiting
Study for newborns with brain or nervous system problems
This study enrolls newborns (within the first 28 days of life) who have specific brain or nervous system conditions. It tests how these conditions are tracked and studied, which may help improve care and understanding over time.
Shanghai, Shanghai MunicipalityAges Up to 4 weeks - NCT05648812RecruitingPhase 3
Ultrasound tests for baby brains using special imaging
This Phase 3 study tests whether detailed ultrasound scans (with contrast and stiffness measurements) can help doctors assess a baby’s brain. It may help by improving how early brain changes are detected in newborn care settings.
Turku, Southwestern FinlandAges 1 minute–6 months - NCT05514340RecruitingPhase 2
Test drug for brain injury after low oxygen at birth
This Phase 2 study tests whether sovateltide can improve safety and outcomes for babies whose brains may have been injured by low oxygen around birth. It focuses on babies who show signs of moderate to severe injury soon after delivery, and who receive standard supportive care.
Mangalore, KarnatakaAges Any age - NCT06746532RecruitingEarly Phase 1
Breast milk nose drops for brain injury in newborns
This trial tests whether giving fresh breast milk as nose drops can help newborns with brain injury from lack of oxygen. It aims to see if this simple treatment can improve brain recovery.
BudapestAges Up to 2 days - NCT06747260RecruitingEarly Phase 1
Breast milk through the nose for HIE
This trial tests whether giving fresh breast milk through the nose is safe and possible for newborns with HIE (a brain injury from oxygen loss at birth) who are already receiving cooling therapy. It may help protect the brain and reduce injury.
BudapestAges Up to 2 days - NCT07165938Recruiting
Genetics of newborn brain injury study
This study looks for genes that may cause or increase the risk of brain injury in newborns. It may help researchers understand why some babies develop encephalopathy and could lead to better treatments in the future.
Boston, MassachusettsAges Any age - NCT05610085RecruitingPhase 2
Levetiracetam for newborn seizures: dose-finding study
This trial studies how to give levetiracetam to newborn babies with seizures. It’s trying to find a safe dose and see if it can help control seizures in early life.
San Diego, CaliforniaAges Up to 1 month - NCT05971446Recruiting
Healthy Little Eyes study for newborn vision and brain health
This study looks at eye and vision outcomes in babies who have had lack of oxygen around birth (HIE) and also compares them with healthy “well babies.” It may help doctors better understand how HIE affects the eyes and what to watch for over time.
Madison, WisconsinAges Up to 3 years - NCT05889507RecruitingPhase 3
Cooling treatment for newborns with mild brain injury
This Phase 3 study tests whether cooling a newborn’s body can help babies with mild brain injury after a difficult birth. It aims to see if cooling improves brain-related outcomes compared with standard care.
NaplesAges 1 hour–6 hours - NCT06098833RecruitingPhase 2
Sildenafil for newborn brain injury after birth asphyxia
This trial tests whether a liquid form of the medicine sildenafil can help repair brain damage in newborns who had a difficult birth and were treated with cooling. If your baby meets the cooling criteria and has brain injury on an MRI, this study may offer an additional treatment option.
Montreal, QuebecAges birth–2 days - NCT07628829Recruiting
Video AI to Monitor Newborn Brain Health
This study uses artificial intelligence to watch and analyze videos of newborns in the hospital nursery or NICU to help doctors spot neurological problems early. The goal is to see if this video AI tool can safely and accurately help care for newborns during their hospital stay.
New York, New YorkAges Any age - NCT05395195RecruitingPhase 3
Erythropoietin for newborn brain injury in low-resource settings
This Phase 3 trial studies whether erythropoietin (a medicine related to red-blood-cell growth) can improve outcomes for newborns with moderate to severe brain injury after birth. The study focuses on babies born in low- and middle-income countries and aims to reduce harm from this early brain condition.
DhakaAges 1 hour–6 hours - NCT07136636Recruiting
Speech development in kids treated for brain injury at birth
This study looks at how children who had a brain injury around birth (HIE) and received cooling therapy are developing speech. It may help families understand language outcomes after this treatment.
BudapestAges birth–7 years - NCT02881970RecruitingPhase 1/Phase 2
Cord blood stem cell treatment for newborn brain injury
This early-phase study tests whether using a baby’s own cord blood stem cells is safe and feasible for newborns with brain injury from lack of oxygen around birth. It may help researchers find new ways to treat hypoxic-ischemic encephalopathy (brain injury due to oxygen deprivation) in addition to standard care like cooling.
MarseilleAges 1 day–3 days - NCT04802135Recruiting
Register for babies with early-onset epileptic brain disorders
This trial builds a long-term list (register) of babies whose seizures start within the first month of life and who need anti-seizure medicine. The goal is to better understand these conditions and support future research that could lead to better care.
AngersAges Any age - NCT07190560Recruiting
Study of a treatment for newborns exposed to chikungunya
This trial tests a new treatment (PC-CHIK-V) for newborns whose mothers had chikungunya around the time of birth. The goal is to see if the treatment can prevent or reduce the infection in babies. Babies who are not treated will also be followed for comparison.
Saint-PierreAges birth–2 days - NCT05836610RecruitingPhase 4
Testing hydrocortisone dosing during newborn cooling
This Phase 4 trial studies the best way to give hydrocortisone (a steroid medicine) to newborns who are being cooled for a specific kind of birth-related lack of oxygen. It’s for babies who have low blood pressure during cooling, aiming to improve their stability while they receive standard treatment.
Budapest, Pest CountyAges Up to 3 days - NCT04225975Recruiting
Study brain activity in babies right after birth
This study measures a newborn’s brain activity immediately after delivery. It may help doctors better understand early brain function in healthy full-term babies.
AmiensAges 1 minute–15 minutes - NCT07275021Recruiting
Brain Injury & Vision Screening in Newborns
This study looks for early signs of vision problems in babies who had brain injuries around the time of birth. It aims to help doctors better identify and predict these issues.
Boston, MassachusettsAges 7 months–10 months - NCT05848271Recruiting
Natural history study for people with HPDL gene changes
This study follows people who have an HPDL gene change to better understand how symptoms and health progress over time. It may help clinicians learn more about the condition and plan future treatments.
San Diego, CaliforniaAges Any age - NCT02793999Recruiting
Near-infrared monitoring to guide cooling in newborns
This study tests a special, non-invasive sensor (near-infrared light) to help doctors choose the best cooling treatment for some newborns after brain injury. It may improve how well cooling works and how safely it’s managed in the first week of life.
Boston, MassachusettsAges Up to 2 years - NCT06522581RecruitingPhase 1
Citicoline for brain injury in newborns
This trial tests if citicoline, a brain-protecting supplement, can help newborns with moderate to severe brain injury from lack of oxygen. It is for babies who have not gotten cooling treatment.
RawalpindiAges 1 day–4 weeks - NCT05754372Recruiting
Dialysis-focused treatment study for newborn high ammonia
This trial looks at how to best treat newborns with very high ammonia in the blood when urgent dialysis is needed. It may help doctors choose the most effective way to rapidly lower ammonia and improve outcomes in babies with certain inherited metabolic conditions.
GhentAges Up to 1 year - NCT07555652Recruiting
Cooling treatment for newborns with birth-related brain injury
This trial studies whether cooling a newborn's body after a difficult birth helps prevent brain damage. Researchers will track babies treated with this cooling therapy and use brain imaging to see how well it works.
Ha Nội, HanoiAges birth–6 hours
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Common questions
- Are there clinical trials for neonatal encephalopathy?
- Yes. Clin2 currently lists 30 recruiting neonatal encephalopathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neonatal encephalopathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neonatal encephalopathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.