Clinical trials
Endothelial Dysfunction clinical trials
Below are recruiting endothelial dysfunction clinical trials, each written for real people, not researchers. We’re tracking 58 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06443151Recruiting
Blood Vessel Health After Spinal Cord Injury
This study looks at how blood vessel health is affected in people with long-term spinal cord injury (over 1 year). It tests whether blood vessel function plays a role in heart and circulatory risk.
Englewood, ColoradoAges 18–89 - NCT07728643Recruiting
Blood vessel particles in children with new high blood pressure
This study looks at tiny particles in the blood (called extracellular vesicles) that may signal early blood vessel changes in children with new high blood pressure. If your child is between 6 and 17, has just been diagnosed with high blood pressure and hasn't started treatment, and is otherwise healthy, this trial may help doctors better understand how high blood pressure affects kids.
OsijekAges 6–17 - NCT05000515Recruiting
Breathing muscle training to lower blood pressure in postmenopause
This study compares a breathing-based exercise program with regular aerobic exercise to help lower blood pressure and improve blood vessel function in postmenopausal women. It’s mainly for people with mildly elevated resting blood pressure who are not already doing very intense workouts.
Boulder, ColoradoAges 50 years+ - NCT04646252Recruiting
Testing a blood-surface feature to prevent heart problems
This study looks at whether a healthy blood lining (the glycocalyx) can help predict and reduce the risk of major heart events in people who have not yet had heart disease. You may be asked to do screening tests and share health information to see how these factors relate to future risk.
Athens, AtticaAges 18–85 - NCT05344573Recruiting
Testing better blood-flow rhythms during heart bypass surgery
This trial studies ways to control the “pulsatility” (how the blood pressure pulses during circulation) while you are on a heart-lung bypass machine. It may help improve safety and heart function during planned heart surgery.
Aurora, ColoradoAges 50–70 - NCT05778981Recruiting
Study of blood-vessel health during non-heart surgery
This study looks at how blood-vessel function changes around the time of non-heart surgery, especially in people 45 and older. It may help doctors better understand risks and recovery related to blood-vessel stress during hospitalization.
Independencia, Santiago MetropolitanAges 45 years+ - NCT06758648Recruiting
Eye blood vessels in Fabry disease
This study looks at the tiny blood vessels in the eyes of people with Fabry disease using a special camera. It may help doctors understand how the disease affects the eyes over time.
München, BavariaAges 18 years+ - NCT07487363RecruitingPhase 1/Phase 2
TB-500 for heart health in stable artery disease
This study tests if TB-500 can improve blood markers of cardiovascular health in people with stable artery disease. It is an early-phase trial to see if the drug is safe and shows promise.
Shenzhen, GuangdongAges 40–75 - NCT07485231Recruiting
Nitric oxide and blood vessel function in women with PTSD
This study tests how well blood vessels work in women with PTSD by measuring nitric oxide levels. It may help understand why PTSD affects heart health and could lead to better treatments.
Minneapolis, MinnesotaAges 18–40 - NCT07422974Recruiting
Surgery results after pre-treatment for colorectal cancer
This study looks at how well patients recover from colorectal cancer surgery, comparing those who had chemotherapy or radiation before surgery to those who did not. The goal is to understand if pre-treatment affects surgical outcomes.
OsijekAges 18 years+ - NCT07311512Recruiting
Gum treatment and mouthwash study for gum disease
This trial tests if a professional gum cleaning combined with a special mouthwash can improve gum health and blood vessel function. It may help people with early gum disease who haven't had recent gum treatment.
Portsmouth, HampshireAges 30–75 - NCT06885970Recruiting
Cytisine for smoking cessation and heart health
This study tests whether a medicine called cytisine can help people quit smoking and how it might affect their heart health. If you are a smoker without serious heart, liver, kidney, or immune problems, you may be able to join.
Athens, HaidariAges 18–75 - NCT05553223Recruiting
Very small activity doses for COPD symptoms
This study tests whether “micro-doses” of physical activity (short, small amounts) can help people with COPD. It aims to see if these small activity bursts are safe and beneficial for people who have stable COPD.
Kelowna, British ColumbiaAges Any age - NCT06776419Recruiting
Heart inflammation and scarring in Fabry disease
This study uses advanced heart scans (PET/CT and MRI) to look at inflammation, blood vessel health, and scarring in the hearts of people with Fabry disease. It aims to better understand how Fabry disease affects the heart and find new ways to track or treat these changes.
CopenhagenAges 18 years+ - NCT03822949Recruiting
Bright light exposure during heart surgery for better recovery
This trial tests whether using bright light at the right time during and after heart surgery helps patients recover more comfortably. It focuses on people having a specific type of open-heart surgery and checks certain heart rhythm and safety factors.
Denver, ColoradoAges 18–90 - NCT05366933RecruitingPhase 1
B-Complex vitamins to protect astronauts during long space missions
This early study tests whether a B-vitamin supplement (called B-Complex) can act as a helpful countermeasure during long stays on the International Space Station. It is only for astronauts assigned to specific 6–12 month missions.
Houston, TexasAges 20–100 - NCT07073352Recruiting
Childhood stress and blood vessel aging in young adults
This study looks at how childhood stress might affect blood vessels and aging in young adults. It tests if a certain protein (SIRT1) is linked to early blood vessel aging.
Iowa City, IowaAges 18–30 - NCT04482374Recruiting
Puberty blockers and heart/metabolic health in teens
This study looks at how puberty suppression (puberty blockers) may affect heart health and metabolism in children who are early in puberty. It may help researchers understand who benefits most and what changes happen during treatment.
Aurora, ColoradoAges 9–14 - NCT05065372RecruitingPhase 1
Metformin test with automated insulin in teens with type 1
This Phase 1 study tests how adding metformin affects blood flow in the kidneys, insulin sensitivity, and overall heart/metabolic health in young people with type 1 diabetes. It may help researchers understand whether this combo is safe and beneficial alongside automated or pump/shot insulin care.
Aurora, ColoradoAges 12–25 - NCT06319274RecruitingPhase 2
Prostacyclin for lung infection patients on a ventilator
This study tests a medicine called prostacyclin (given through a vein) to see if it helps people on a breathing machine with a lung infection. The goal is to reduce inflammation and improve recovery.
CopenhagenAges 18 years+ - NCT06489249RecruitingEarly Phase 1
Study on vaping, inflammation, and blood vessel health
This study looks at how vaping (e-cigarettes) might affect inflammation and blood vessel health in young adults. You will be asked to take a drug called salsalate to see if it changes these effects.
Iowa City, IowaAges 18–24 - NCT06454344Recruiting
Sleep and childhood experiences study in young adults
This study looks at how sleep is affected by tough childhood experiences. It tests whether changing sleep patterns can help young adults who have had these experiences and currently have poor sleep.
Iowa City, IowaAges 18–29 - NCT05808686RecruitingPhase 2
Exercise-based training for circulation in older, frail adults
This study tests a special exercise training approach to help small blood vessels work better and improve resilience in frail older adults. If you join, you’ll do training that may involve temporary blood-flow restriction, so safety rules are important.
Wauwatosa, WisconsinAges 65–85 - NCT06308952RecruitingPhase 4
Atorvastatin before flow diverter for brain aneurysms
This trial tests whether taking atorvastatin before a flow diverter procedure can prevent strokes or other brain events in people with unruptured brain aneurysms. It may help reduce complications from the treatment.
Guangzhou, GuangdongAges 18–75
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Common questions
- Are there clinical trials for endothelial dysfunction?
- Yes. Clin2 currently lists 58 recruiting endothelial dysfunction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a endothelial dysfunction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a endothelial dysfunction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.