Clinical trials
Epilepsy clinical trials
Below are recruiting epilepsy clinical trials, each written for real people, not researchers. We’re tracking 328 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07713706Enrolling by invitation
Brain activity study for speech production
This study looks at how the brain stops speech, using electrical recordings taken during your already-planned epilepsy monitoring. It may help understand speech control.
Pittsburgh, PennsylvaniaAges 8–26 - NCT05724719Recruiting
Study brain signals after a first unprovoked seizure
This study looks at people ages 18 to 65 after they have a first seizure that is not clearly triggered. It also compares them with healthy volunteers to better understand what might predict whether seizures come back.
Halifax, Nova ScotiaAges 18–65 - NCT07663578Recruiting
Brain stimulation study for epilepsy patients and healthy volunteers
This study tests a new non-invasive brain stimulation method called TIEFS. It uses safe electric fields to see how it affects thinking and brain waves. You may join if you are having brain surgery for epilepsy or are a healthy adult.
Sacramento, CaliforniaAges 18–65 - NCT05254730Recruiting
Testing brain-recording sensors to map the seizure source
This study looks at using special tiny filaments during brain monitoring to better identify where seizures start. It’s meant for people with hard-to-control (refractory) epilepsy who are already being considered for a specific brain-monitoring procedure.
Montreal, QuebecAges Any age - NCT03953768Recruiting
Testing a new vagus nerve stimulator for gut and immune health
This study looks at what happens to your immune system and stomach/gut function after getting a vagus nerve stimulator (VNS) for the first time for epilepsy. It may help doctors understand whether the device benefits more than seizures.
Louisville, KentuckyAges birth–60 years - NCT07605858Recruiting
Epilepsy, Sleep, and Brain Activity Study
This study examines how seizures affect sleep quality and dreams in people with hard-to-treat focal epilepsy. Researchers will use specialized brain electrodes to understand these connections during sleep, which may help improve treatment in the future.
Durham, North CarolinaAges 18–55 - NCT07595666Enrolling by invitation
New PET scanner versus standard PET for head and neck imaging
This study compares a newer PET/CT scanner (called NeuroEXPLORER) with standard PET/CT scanners for imaging the head and neck region. The goal is to see if the new scanner provides better or clearer images to help diagnose conditions.
Leuven, Vlaams-BrabantAges 4 weeks+ - NCT07594158RecruitingPhase 3
ONO-2017 for Seizures in Japanese Children and Teens
This study tests a new seizure medication called ONO-2017 in Japanese children and teenagers (ages 2–17) who have a specific type of seizure called POS that hasn't been controlled by current medicines. The goal is to see if this new drug is safe and helps reduce these seizures.
FukuokaAges 2–17 - NCT05725174Recruiting
Study seizure signals using quick, non-invasive breath tests
This study looks for “volatile” (gaseous) body signals from breath to help identify seizure events. If you were recently admitted for seizure diagnosis, you may be asked to provide breath samples in a non-invasive way.
London, BuckinghamshireAges 18 years+ - NCT07594652RecruitingPhase 4
ADHD Treatment for Children With Epilepsy
This study tests whether a specific ADHD medication (Jornay PM) is safe and helpful for children who have both epilepsy and ADHD. Researchers want to see if treating ADHD can improve focus and behavior without making seizures worse.
Baltimore, MarylandAges 6–17 - NCT06545708Recruiting
Music perception in children with SeLECTs epilepsy
This study looks at how children with a specific type of epilepsy (SeLECTs) and healthy children perceive music. It aims to understand if music perception is different in children with this condition.
Bron, BronAges 5–14 - NCT04717388Recruiting
Study brain and feelings in people with tinnitus
This study looks at how tinnitus affects the brain, thinking, and emotional well-being. It compares people with chronic tinnitus to people without tinnitus (including a group related to a specific type of epilepsy surgery).
ParisAges 18 years+ - NCT07544563Recruiting
Brain Activity During Sound Testing
This study measures how your brain responds to sounds in a specially designed quiet room. Researchers want to understand how epilepsy affects sound processing, which could help improve treatment in the future.
ParisAges 18 years+ - NCT06278428Recruiting
Epilepsy in Infants: Genes and Disease Course
This study looks at children with severe epilepsy that starts before age 2. It aims to understand how different gene changes affect the disease and how it progresses over time.
Ho Chi Minh CityAges Up to 1.9 years - NCT06667232Recruiting
Burst stimulation for epilepsy using implanted electrodes
This trial tests a new way to stimulate the brain using bursts of electrical pulses in people with drug-resistant epilepsy. It might help find better treatment options for those who are already undergoing SEEG monitoring as part of their presurgical evaluation.
Beijing, Beijing MunicipalityAges 14–65 - NCT07460037Recruiting
Brain signal study for speech recovery after stroke or injury
This trial uses a special brain-mapping test called high-density ECoG to study how people who have lost speech due to stroke, brain tumor, or ALS can be helped by reading brain signals when they imagine speaking. It may lead to new devices that let people with severe speech problems communicate using only their thoughts.
Hangzhou, ZhejiangAges 20–80 - NCT07454785Enrolling by invitation
How the brain learns new patterns
This study looks at how the brain learns and uses patterns. If you have epilepsy that requires brain monitoring, you may be able to join and help researchers understand memory and thinking.
Los Angeles, CaliforniaAges 18 years+ - NCT07445074Recruiting
AI phone app to help teens and young adults with epilepsy take their medicine
This study tests a mobile app that uses artificial intelligence to help people with epilepsy remember to take their anti-seizure medication. It is for teens and young adults (ages 14-24) living in Florida who are from underserved communities.
Orlando, FloridaAges 14–24 - NCT06663969Recruiting
Temporal Interference Stimulation for Epilepsy
This trial tests a new, gentle way to stimulate specific brain areas using a special electrical signal. It aims to see if this can help people with epilepsy that hasn't improved with medication.
Beijing, Beijing MunicipalityAges 14–65 - NCT07417280Recruiting
Focused ultrasound for neurological disorders
This trial tests a gentle ultrasound treatment (LIFUS) for people with various brain conditions like epilepsy, tumours, or movement disorders. It aims to see if this non-invasive approach can help where other treatments are being used.
Toronto, OntarioAges 18–85 - NCT07403266RecruitingPhase 3
Full-spectrum cannabis oil for seizures in tuberous sclerosis
This trial tests a full-spectrum cannabis extract to see if it reduces seizures in people with tuberous sclerosis complex (TSC) whose seizures have not been controlled by other treatments. If it works, it could offer a new option for managing hard-to-treat epilepsy.
MadridAges 2–65 - NCT07399327Recruiting
SEEG thermocoagulation for hard-to-treat epilepsy
This study is looking at how well a procedure called SEEG thermocoagulation (a way to stop seizures by heating a small area of brain tissue) works for people with epilepsy that doesn't improve with medication. By joining, you will help doctors understand why this treatment works for some people and not others.
MarseilleAges 12 years+ - NCT06836687Recruiting
How a new epilepsy definition affects diagnosis after a first seizure
This study looks at how the new 2014 definition of epilepsy from the ILAE affects diagnosis after a first seizure. It is for adults who have had their very first seizure and can give consent.
Marburg, HesseAges 18 years+ - NCT07377032RecruitingPhase 3
L-serine for GRIN-related neurodevelopmental disorders
This trial tests whether an amino acid supplement called L-serine can help people with GRIN-related neurodevelopmental disorders. These disorders are caused by specific genetic changes that affect brain function, and the study aims to see if L-serine can improve symptoms.
LyonAges 2–30
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Common questions
- Are there clinical trials for epilepsy?
- Yes. Clin2 currently lists 328 recruiting epilepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.