Clinical trials
Epilepsy clinical trials
Below are recruiting epilepsy clinical trials, each written for real people, not researchers. We’re tracking 339 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01238250Recruiting
Online autism genetics study for families with certain genetic changes
This study asks people with specific genetic changes linked to autism and their family members to complete online tasks and questionnaires. It may help researchers better understand how these genetic differences relate to autism traits.
Boston, MassachusettsAges Any age - NCT04526093Recruiting
Study of medical cannabis using patient symptom reports
This study looks at how medical cannabis affects symptoms like pain, epilepsy, sleep, and anxiety or depression, based on what patients report over time. It may help researchers understand what works in real life when people use verified medical cannabis products.
Toronto, OntarioAges 19 years+ - NCT07713706Enrolling by invitation
Brain activity study for speech production
This study looks at how the brain stops speech, using electrical recordings taken during your already-planned epilepsy monitoring. It may help understand speech control.
Pittsburgh, PennsylvaniaAges 8–26 - NCT03819738Recruiting
Brain scan during deep brain stimulation
This study checks how brain imaging works in people who already have a deep brain stimulation (DBS) device. If you have a DBS system, the study may help researchers better understand what the stimulation is doing in the brain.
Leuven, Vlaams-BrabantAges 18 years+ - NCT03912155Recruiting
Brain network study using implanted brain electrodes for epilepsy
This study looks at how brain connections work in people with drug-resistant partial epilepsy by analyzing signals from implanted electrodes done before surgery. It may help doctors better understand epilepsy and improve future pre-surgical evaluation.
MarseilleAges 12 years+ - NCT03945968Recruiting
Risk scores after abdominal surgery for people with health conditions
This study looks at how other health problems affect the chance of postoperative complications after abdominal surgery. It aims to help doctors better predict risk and decide on the safest care for you.
ArkhangelskAges 18 years+ - NCT03953768Recruiting
Testing a new vagus nerve stimulator for gut and immune health
This study looks at what happens to your immune system and stomach/gut function after getting a vagus nerve stimulator (VNS) for the first time for epilepsy. It may help doctors understand whether the device benefits more than seizures.
Louisville, KentuckyAges birth–60 years - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT05989893Recruiting
Mapping human thinking during brain surgery
This study maps how thinking works in people with epilepsy or brain lesions near important brain areas. It involves testing during brain surgery procedures to help researchers understand healthy brain function.
Houston, TexasAges 18–75 - NCT04134754Recruiting
Testing how your brain responds to carbon dioxide in epilepsy
This study measures how sensitive your brain is to higher carbon dioxide levels to learn more about sudden unexpected death in epilepsy (SUDEP). You may be invited because you have epilepsy and are having evaluation at a specialized epilepsy unit or clinic.
Iowa City, IowaAges 18–99 - NCT04322734Recruiting
Blood tests study immune and metabolism markers in neurodevelopment
This study looks for biological “signals” in blood—related to the immune system and metabolism—to better understand conditions like autism and other brain or development-related disorders. It may help researchers find markers that could guide future diagnosis or treatment.
Phoenix, ArizonaAges Up to 18 years - NCT04653012Recruiting
Testing brain-activity recordings in people with drug-resistant epilepsy
This study looks at brain activity using electrodes placed inside the brain in people with focal, drug-resistant epilepsy before surgery. It may help doctors better map where seizures start and improve planning for treatment.
ParisAges 18 years+ - NCT04677751Recruiting
Testing acupuncture effects in people with an implanted seizure device
This study looks at how adding acupuncture may change seizure activity in people who already have an implanted RNS seizure monitor and stimulator. You might benefit by learning whether acupuncture helps with seizure patterns without changing your usual treatments.
Houston, TexasAges 15–60 - NCT04715646RecruitingPhase 3
Brivaracetam study for children with hard-to-control seizures
This trial looks at how safe brivaracetam is and how well it can be used in children and teens with certain types of epilepsy that are not well controlled. It may help families who are dealing with frequent focal seizures despite taking seizure medicines.
Hawthorne, New YorkAges 1 month+ - NCT04717388Recruiting
Study brain and feelings in people with tinnitus
This study looks at how tinnitus affects the brain, thinking, and emotional well-being. It compares people with chronic tinnitus to people without tinnitus (including a group related to a specific type of epilepsy surgery).
ParisAges 18 years+ - NCT04861051RecruitingPhase 1
Study ketamine effects on brain sensations in adults
This Phase 1 study tests how ketamine changes “dissociative” experiences—feelings of being disconnected from thoughts or surroundings—in adults. You may be helping researchers better understand ketamine’s effects, which could guide safer future uses.
Palo Alto, CaliforniaAges 18 years+ - NCT06700356Recruiting
Can a brain stimulator detect seizures in the thalamus?
This study tests whether a special brain stimulator (already implanted in some people with epilepsy) can detect seizures in the thalamus. It may help improve seizure monitoring without extra surgery.
Rochester, MinnesotaAges 18 years+ - NCT05065450Recruiting
Testing whether brain stimulation improves memory in epilepsy
This trial looks at ways to improve memory by targeting specific deep brain areas in people with epilepsy. You may be eligible if you are already scheduled for long-term video monitoring with implanted depth electrodes in the memory-related regions (amygdala, hippocampus, and nearby areas).
St Louis, MissouriAges 18–75 - NCT05085704Recruiting
Brain scans to study metabolism in healthy and diabetic people
This study uses MRI brain scans at different strengths to measure how the brain uses energy (metabolism) in health and in people with genetically confirmed G1D. It may help researchers understand brain energy changes related to metabolic disease and diabetes.
New York, New YorkAges 16–80 - NCT05101161Recruiting
Neurofeedback delivered through implanted brain stimulation
This study tests a brain “feedback” approach using electrodes already placed as part of standard medical care. It aims to see whether this method is safe and helpful for people undergoing deep brain stimulation after surgery.
Zurich, Canton of ZurichAges 18 years+ - NCT05126914Recruiting
Follow-up study for rare epilepsy in children
This study follows children and teens with rare forms of epilepsy to better understand their condition over time in real-life care. It may help doctors improve future care plans and support for families.
AngersAges Up to 15 years - NCT05140265Recruiting
Uses EEG and medical records to build a privacy-protected database
This study creates a large, de-identified database by combining EEG test recordings with basic clinical information from medical records. It helps researchers use brain-wave data for future research while protecting your identity.
Albuquerque, New MexicoAges 18 years+ - NCT05222594Recruiting
Brain language study using electrodes during epilepsy care
This study looks at how the brain processes language using recordings from electrodes placed during epilepsy treatment. If you’re already being considered for this type of brain monitoring, the study’s tasks may help researchers better understand language function in the brain.
Boston, MassachusettsAges 18–85 - NCT05223985Recruiting
Testing a brain-recording device for focal epilepsy mapping
This study tests how well a specific brain-recording device works during a procedure used to map seizure origins in people with drug-resistant, disabling focal epilepsy. It may help doctors plan treatment by improving how well they can localize the seizure focus before possible surgery.
MarseilleAges 1.5 years–65 years
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Common questions
- Are there clinical trials for epilepsy?
- Yes. Clin2 currently lists 339 recruiting epilepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.