Clinical trials
Epilepsy clinical trials
Below are recruiting epilepsy clinical trials, each written for real people, not researchers. We’re tracking 339 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT00859794Enrolling by invitation
Study brain and movement functions in people with difficult epilepsy
This study looks at how the brain and body coordination work in people with epilepsy whose seizures do not fully respond to seizure medicines. Some participants may be people who are being evaluated for a possible epilepsy surgery because tests suggest they could benefit.
Great Neck, New YorkAges 5 years+ - NCT07490769RecruitingPhase 3
Taking levetiracetam three times daily for epilepsy
This trial is for adults with uncontrolled epilepsy who have been taking a high dose of Levetiracetam alone for at least a year. It tests whether taking Levetiracetam three times a day works better than the usual schedule.
Riyadh, Riyadh RegionAges 18 years+ - NCT07509190Recruiting
Helping patients learn about epilepsy surgery
This study aims to improve access to epilepsy surgery by educating patients about social factors that affect health. It includes surveys and focus groups for people with epilepsy who have undergone surgery evaluation at Cleveland Clinic.
Cleveland, OhioAges 18 years+ - NCT07509177Recruiting
Infrared light therapy for stress in epilepsy
This trial tests if infrared light therapy can help reduce stress in people with epilepsy. You would wear a ring to track your sleep and activity, and attend 45 light therapy sessions over several months.
North Miami, FloridaAges 18 years+ - NCT07588971Recruiting
Understanding childhood epilepsy outcomes and long-term patterns
This study tracks children with epilepsy to understand how different types progress over time and what factors affect their outcomes. By learning more about your child's epilepsy journey, researchers hope to improve how doctors predict and manage the condition.
RomeAges Up to 18 years - NCT07592676Recruiting
Moving from pediatric to adult epilepsy care
This study looks at how young people with epilepsy transition from pediatric (children's) specialists to adult neurologists. Researchers want to understand what helps or challenges this transition to improve the care experience.
RomaAges 15 years+ - NCT07651709Recruiting
Bone Health During Pregnancy in Women With Epilepsy
This study looks at how epilepsy and epilepsy medications affect bone health during pregnancy and after delivery. Researchers want to understand how to keep bones strong while you're pregnant and taking seizure medications, which can sometimes weaken bones.
ZhejiangAges 18 years+ - NCT07663240Enrolling by invitation
Program to help women with epilepsy reduce ER visits
This study is for Black or Hispanic women with epilepsy who often go to the emergency room for seizures. It aims to help reduce ER visits by connecting you with better follow-up care and support.
Atlanta, GeorgiaAges 18 years+ - NCT07474285Enrolling by invitation
Cenobamate for autoimmune epilepsy
This trial tests whether a new seizure medicine (cenobamate) helps people whose seizures are caused by an overactive immune system. You would stay on your current treatments and add cenobamate to see if it reduces seizures.
Rome, LazioAges 18 years+ - NCT06952764Enrolling by invitation
ECLIPSE: Tracking epilepsy cycles to predict seizures
This trial tests if tracking your brain activity with an implanted device can help predict when seizures might happen. It is for adults who have seizures despite medication and already have the RNS System implanted.
San Francisco, CaliforniaAges 18 years+ - NCT06716866Enrolling by invitation
Electric field stimulation for epilepsy
This trial tests a new type of brain stimulation using electric fields to treat epilepsy, specifically for people who are already having invasive EEG monitoring as part of their care.
Sacramento, CaliforniaAges 18 years+ - NCT06376279Enrolling by invitation
Genetic testing for metabolic diseases
This trial uses genetic testing to find the cause of suspected metabolic diseases, including some cases of epilepsy. It may help you get a clearer diagnosis and guide treatment.
Ages Any age - NCT06369571Enrolling by invitationPhase 1/Phase 2
Improving heart health in adults with epilepsy on a modified Atkins diet
This study tests whether a statin medication (atorvastatin) can help lower cholesterol and improve heart health in adults with epilepsy who have been on a modified Atkins diet for a year or more. It may be a good fit if you have high cholesterol and are not already on a statin or have had heart problems.
Baltimore, MarylandAges 18 years+ - NCT04788628Enrolling by invitation
Sound stimulation study for sleep and memory in epilepsy
This trial studies whether carefully timed sound (“auditory stimulation”) can change sleep patterns and memory in people with epilepsy. It may help researchers understand how to improve thinking and memory by adjusting how the brain sleeps.
Boston, MassachusettsAges 12–65 - NCT06275685Recruiting
Forecasting seizures with a smart wearable
This study tests if a smart wristband called EmbracePlus can predict seizures. You wear the device and track your seizures to see if it can warn you ahead of time.
Boston, MassachusettsAges 6 years+ - NCT07753681Recruiting
Chronic disease care in Zambia
This study helps improve care for people with long-term illnesses like diabetes or high blood pressure in Zambia. It aims to make sure you get regular check-ups and support.
Lusaka, Lusaka ProvinceAges Any age - NCT07156201RecruitingPhase 1
Safety study of oral ABS-1230 in healthy adults
This trial tests a new oral medication called ABS-1230 in healthy people to see how safe it is and how the body processes it. You would take either the drug or a placebo (no active ingredient) and be monitored closely.
Sydney, New South WalesAges 18–55 - NCT06865820Recruiting
Testing Project UPLIFT for people with epilepsy
This study tests whether a program called Project UPLIFT helps people with epilepsy feel better. It uses phone or online sessions to teach skills and support mental health.
Atlanta, GeorgiaAges 18 years+ - NCT07750496RecruitingPhase 4
Stopping seizure medications in adults with epilepsy
This study looks at what happens when people with epilepsy stop their seizure medications. The goal is to see if it's safe to stop after being seizure-free for a while, and to help patients and doctors make better decisions.
Ann Arbor, MichiganAges 18 years+ - NCT05327387Recruiting
Brain stimulation study using implanted electrodes
This study tests a model-based way of using electrical brain stimulation in people who are having surgery for drug-resistant epilepsy or brain tumors. It uses implanted electrodes to measure brain activity and may help improve how stimulation is planned during surgical care.
Los Angeles, CaliforniaAges 18 years+ - NCT05273970Enrolling by invitation
Brain recording study during electrode surgery for drug-resistant epilepsy
This study uses special brain recordings done during electrode implantation to better understand brain activity in people whose symptoms are hard to control with medications. The goal is to help doctors improve how they evaluate and treat certain brain or nerve conditions.
Phoenix, ArizonaAges 18–80 - NCT07110688Recruiting
Brain sensing study for mental states
This trial uses sensors and machine learning to understand mental states in healthy adults and people with epilepsy. Researchers aim to improve how we monitor and support mental health.
Downey, CaliforniaAges 18 years+ - NCT07594652RecruitingPhase 4
ADHD Treatment for Children With Epilepsy
This study tests whether a specific ADHD medication (Jornay PM) is safe and helpful for children who have both epilepsy and ADHD. Researchers want to see if treating ADHD can improve focus and behavior without making seizures worse.
Baltimore, MarylandAges 6–17 - NCT07725601Recruiting
VNS dosing algorithm for epilepsy
This trial tests a new way to adjust the settings on a Vagus Nerve Stimulator (VNS) to better control seizures in people with epilepsy. It is for those who are already getting a VNS implanted to treat their seizures.
Augusta, GeorgiaAges 18–75
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Common questions
- Are there clinical trials for epilepsy?
- Yes. Clin2 currently lists 339 recruiting epilepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.