Clinical trials
Epilepsy clinical trials
Below are recruiting epilepsy clinical trials, each written for real people, not researchers. We’re tracking 339 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05254730Recruiting
Testing brain-recording sensors to map the seizure source
This study looks at using special tiny filaments during brain monitoring to better identify where seizures start. It’s meant for people with hard-to-control (refractory) epilepsy who are already being considered for a specific brain-monitoring procedure.
Montreal, QuebecAges Any age - NCT05285059Recruiting
Study how children with epilepsy learn
This trial studies how children with epilepsy learn and process information compared with children without brain, mental health, or learning conditions. It may help researchers understand the learning needs of children living with epilepsy.
Bron, BronAges 8–14 - NCT05289934Recruiting
Recorded music to see how it affects seizures
This study is testing whether listening to recorded music can change seizure activity and brain-wave patterns in children monitored in an epilepsy center. Your child might benefit by helping researchers learn how music could affect seizures during close observation.
Baltimore, MarylandAges 4–17 - NCT05313308Recruiting
Survey of midazolam use in non-convulsive seizure emergencies
This trial is a survey about how midazolam is used in people with non-convulsive status epilepticus, especially when it’s given outside a medical facility and when an extra dose is needed. It may help doctors better understand real-world treatment patterns and safety.
TokyoAges Any age - NCT05339438Recruiting
Brain scan mapping before epilepsy surgery
This study uses a special MRI scan to map parts of the front-temporal brain in people with drug-resistant epilepsy who may need surgery. The goal is to better plan surgery by showing which brain areas are involved.
NancyAges 18 years+ - NCT05393518Recruiting
Study linking brain signals to anxiety in people with epilepsy
This study looks at how brain electrical signals relate to anxiety symptoms in people with drug-resistant epilepsy. It compares people who do (or do not) meet criteria for generalized anxiety disorder, to better understand anxiety in this setting.
BordeauxAges 18–65 - NCT05406349Recruiting
Study of brain activity for space memory using epilepsy implants
This study looks at how your brain represents locations in space, including how it relates to you (beyond your “self”). It uses special epilepsy-related implants or procedures to record brain activity, which may help researchers understand spatial thinking.
Boston, MassachusettsAges 18–70 - NCT05418894Recruiting
Study brain signals and improve treatment-resistant depression
This trial studies how brain activity relates to feelings and depression, using brain electrodes to measure signals. It’s meant for people with long-lasting, treatment-resistant major depression who may need stimulation while continuing psychiatric care.
Houston, TexasAges 22–70 - NCT05450978Recruiting
Study drug levels in epilepsy meds during pregnancy and breastfeeding
This study measures how much epilepsy medicine (lamotrigine, levetiracetam, or oxcarbazepine) your body absorbs during pregnancy and breastfeeding. It may help doctors better understand dosing and safety during these times.
Pittsburgh, PennsylvaniaAges 18–45 - NCT05459090Recruiting
Study of how brain “brakes” work in drug-resistant temporal epilepsy
This study looks at how the brain’s natural “braking” system works in people with drug-resistant temporal lobe epilepsy. It may help researchers better understand the condition in order to improve future treatments.
Pozzilli, IserniaAges Any age - NCT05469373Recruiting
Testing ESIS for children with hard-to-treat epilepsy
This trial studies ESIS in children and teens (ages 1 to 30) who have epilepsy that has not been controlled by medications. It may help by improving how doctors evaluate and treat seizures, especially when an additional brain-monitoring test is planned.
Cincinnati, OhioAges 1–30 - NCT05529264Recruiting
EEG study in adults with epilepsy and brain recordings
This study uses brain recordings to better understand epilepsy signals. It may help people who need EEG monitoring for clinical care, and it may also use healthy adults as comparison participants.
Lebanon, New HampshireAges 18 years+ - NCT05534672RecruitingPhase 3
Rapamycin for drug-resistant seizures in tuberous sclerosis
This trial tests whether rapamycin (compared with a placebo) can reduce seizures caused by tuberous sclerosis complex (TSC) that have not been controlled by usual medicines. If you qualify, you may be helping doctors find a safer and more effective option for seizure control.
LodzAges 3 months–50 years - NCT05594017RecruitingEarly Phase 1
Test medicine to change brain rhythms and study memory
This early research study tests whether a medicine can change the brain’s electrical “rhythms” while people do memory-related tasks. It may help researchers understand how brain timing affects memory in people who are already being evaluated with specialized brain electrode monitoring.
Dallas, TexasAges 18–55 - NCT05600738Recruiting
Deep brain stimulation to treat epilepsy
This trial studies how adding or using deep brain stimulation devices affects people with epilepsy. It may help researchers understand which outcomes improve when these implanted devices are used.
Houston, TexasAges 18 years+ - NCT05638269Recruiting
Study of gut bacteria in people with serious long-term illness
This study looks at the types of gut bacteria in people living in certain parts of China who have serious long-term (chronic) illnesses. The goal is to better understand how gut bacteria differ and may help doctors in the future tailor care.
Chaoyang, Beijing MunicipalityAges 18–75 - NCT05664854Recruiting
Vagus nerve stimulation guided by body imaging
This study uses a painless body scan method (electrical impedance imaging) and a targeted vagus nerve stimulation to see if it helps people with conditions that might respond to this kind of nerve treatment. If you may benefit from vagus nerve stimulation, this trial may help doctors learn whether the approach is effective and safe for you.
London, Greater LondonAges 18 years+ - NCT05688683Recruiting
Brain recording during awake surgery to study motor learning
This study uses special brain recordings during an awake surgical procedure to understand how the brain learns new movement and sensation skills. If you can comfortably take part in a simple task during surgery, you may help researchers learn how learning works in humans.
ParisAges 18 years+ - NCT05724719Recruiting
Study brain signals after a first unprovoked seizure
This study looks at people ages 18 to 65 after they have a first seizure that is not clearly triggered. It also compares them with healthy volunteers to better understand what might predict whether seizures come back.
Halifax, Nova ScotiaAges 18–65 - NCT05725174Recruiting
Study seizure signals using quick, non-invasive breath tests
This study looks for “volatile” (gaseous) body signals from breath to help identify seizure events. If you were recently admitted for seizure diagnosis, you may be asked to provide breath samples in a non-invasive way.
London, BuckinghamshireAges 18 years+ - NCT05819008Recruiting
Online brain testing for people with neurological conditions
This trial studies how well a remote, online memory and thinking assessment works for people with neurological disorders or injuries. You may be invited if you can do the computer-based testing and speak Swedish.
UmeåAges 18 years+ - NCT05854160Recruiting
Brain stimulation study during epilepsy surgery evaluation
This trial studies how stimulating the brain changes communication between parts of the brain involved in emotion and memory. You may be able to join if you are already having epilepsy surgery and doctors will place specific brain electrodes as part of your evaluation.
Birmingham, AlabamaAges 18 years+ - NCT05863910Recruiting
Real-world study of medical cannabis use in children
This study looks at how medical cannabis is used for children and teens in everyday life, by collecting information through online questionnaires. It may help doctors and families better understand which uses are common and how people experience them.
Winnipeg, ManitobaAges 3–17 - NCT05865561Recruiting
Breath and skin tests to predict epileptic seizures
This study looks for specific chemicals in a person’s breath or skin (volatile organic compounds) that might help predict seizures. It’s mainly for adults with drug-resistant epilepsy who will undergo at least 48 hours of video EEG monitoring.
ParisAges 18 years+
Hear when a new Epilepsy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for epilepsy?
- Yes. Clin2 currently lists 339 recruiting epilepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.