Clinical trials
Glioma clinical trials
Below are recruiting glioma clinical trials, each written for real people, not researchers. We’re tracking 331 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07346144RecruitingPhase 1/Phase 2
Gene therapy study for high-grade glioma
This trial tests a new gene therapy given directly into the brain tumor. It's for people with high-grade glioma, either newly diagnosed or after one recurrence, to see if it can help control the tumor.
Columbus, OhioAges 18–70 - NCT07126990Enrolling by invitationPhase 1/Phase 2
A new virus therapy for untreated high-grade glioma
This trial tests a modified virus that may help treat a type of brain cancer called high-grade glioma. It is for patients who have not yet had any treatment for their tumor.
Beijing, Chaoyang DistrictAges 18–80 - NCT07076498RecruitingPhase 1
Gene therapy for children and adults with diffuse midline glioma
This trial tests a modified herpes virus (M032) given directly into the brain tumor after standard radiation. The goal is to see if this virus can slow or stop the growth of diffuse midline glioma, a type of brain cancer.
Houston, TexasAges 3 years+ - NCT07465796Recruiting
Testing a new device during brain tumor surgery
This trial is testing a new tool called the CIPHER System during brain surgery for people with a newly diagnosed glioma. It looks at how well the tool works and how safe it is when used during the procedure.
Melbourne, VictoriaAges 18–75 - NCT07631338Recruiting
Low-Grade Brain Tumors: Treatment Outcomes in Argentina
This study follows adults with low-grade gliomas (slow-growing brain tumors) to understand how often they occur, how long patients survive, and which treatments work best. Researchers will review medical records to learn more about care options.
Buenos Aires, Buenos Aires F.D.Ages 18 years+ - NCT07649070RecruitingPhase 2
Virus therapy and low-dose radiation for children with aggressive brain cancer
This trial tests whether a special herpes virus (G207) combined with low-dose radiation can help children with high-grade brain tumors (gliomas). The virus is injected into the tumor to attack the cancer cells while radiation helps boost the effect.
Houston, TexasAges 3–21 - NCT07832734Recruiting
Brain tumor tissue analysis for glioma diagnosis
This study looks at the chemicals and genes in brain tumors called gliomas to find better ways to diagnose and treat them. People with a brain mass that needs surgery may be able to join.
Milan, LombardyAges 18 years+ - NCT07488780Recruiting
Language brain training before brain surgery
This study tests whether a special MRI training session can help preserve your language abilities before brain surgery. It uses real-time feedback to strengthen the language network in your brain.
New Haven, ConnecticutAges 18 years+ - NCT05564949Recruiting
Ketogenic diet for brain tumors after standard treatment
This trial studies whether a very low-carbohydrate diet (a ketogenic diet) can help people with certain brain tumors. It’s meant as an added treatment alongside the usual care to see if it’s safe and potentially beneficial.
Chaïdári, AthensAges 18–80 - NCT07017816RecruitingEarly Phase 1
Gene therapy, checkpoint inhibitor, and radiation for children with brain cancer
This trial tests a new combination treatment for children and young adults with brain tumors that have come back or not responded to standard therapy. The treatment includes a gene therapy (SGT-53) that delivers a normal TP53 gene, a checkpoint inhibitor drug that helps the immune system attack the cancer, and focused radiation. The goal is to see if this combination is safe and can shrink tumors.
Washington D.C., District of ColumbiaAges 3–21 - NCT07003542RecruitingPhase 2
Sitagliptin for people with high-grade brain tumors
This trial tests whether sitagliptin, a medicine usually used for diabetes, can help people with a fast-growing type of brain tumor (grade 4 glioma). You will take sitagliptin before your planned surgery, and researchers will study how it affects your tumor.
Cleveland, OhioAges 18 years+ - NCT06988475RecruitingPhase 2/Phase 3
Capmatinib for cancers with MET gene changes
This study tests an oral drug called capmatinib for people whose cancers have specific changes in the MET gene (except for one type of lung cancer). It aims to see if the drug can shrink tumors or slow their growth.
BelfastAges 18 years+ - NCT06942104RecruitingPhase 1
New imaging agent for advanced solid tumors
This trial tests a new imaging agent (18F-TRX) to see if it can better detect cancer spread in people with advanced solid tumors. It is designed for patients with specific cancers like high-grade brain tumors, advanced kidney cancer, or prostate cancer that has stopped responding to hormone therapy.
San Francisco, CaliforniaAges 18 years+ - NCT06930846Recruiting
Brain cancer cognitive training study
This study tests a home-based program called HOBSCOTCH-CA to help with memory and thinking problems after brain cancer treatment. The program uses phone and internet sessions to teach self-management skills.
Lebanon, New HampshireAges 18 years+ - NCT04111588Recruiting
PET/MRI scan to assess brain tumors and metastases
This trial tests how well a special PET/MRI scan can help doctors evaluate gliomas and brain metastases. It may help improve diagnosis and treatment planning by comparing scan results with tissue samples or surgery findings.
BergenAges 18 years+ - NCT06914479RecruitingPhase 1
Gene therapy and valacyclovir for recurrent brain tumors in young people
This trial tests a new gene therapy that uses two special viruses and an oral antiviral drug (valacyclovir) to treat brain tumors that have come back in children and young adults. The therapy is given right after surgery to remove the tumor, with the goal of helping your immune system fight the cancer.
Ann Arbor, MichiganAges 3–39 - NCT06917885RecruitingPhase 1
CUE-102 for Recurrent Glioblastoma: A Safety Study
This study tests an experimental drug, CUE-102, for people with recurrent glioblastoma. It aims to see if the drug is safe and how well it works. You may be eligible if your tumor has come back once, you have a specific genetic marker (HLA-A*0201), and you are not on other treatments.
Boston, MassachusettsAges 18 years+ - NCT06910306Recruiting
DaRT alpha radiation for recurrent glioblastoma
This trial tests a device called DaRT that delivers alpha radiation directly to a recurrent glioblastoma tumor. It may help patients who cannot have surgery and have a single, small tumor regrowth.
Scottsdale, ArizonaAges 18–85 - NCT06831461Recruiting
Proton vs photon radiation for brain tumors
This study compares two types of radiation therapy for adults with primary brain tumors that have a good outlook (expected survival longer than 5 years). You will receive either standard photon radiation or the more targeted proton radiation, to see if one works better or causes fewer side effects.
MumbaiAges 18–70 - NCT06804655RecruitingPhase 2
Personalized drug testing for stubborn brain tumors
This study tests a new way to choose treatment for people with brain tumors that have not responded to standard therapies. Your tumor sample is analyzed in the lab to find which drugs might work best for you, and then you receive a personalized treatment plan.
Basel, Basel-LandschaftAges 18 years+ - NCT06797661Recruiting
Brain lesion blood flow study before surgery
This study looks at how blood flow in the brain changes when there is a mass that can be removed with surgery. You would join before any treatment, which helps doctors understand the link between the brain lesion and blood vessel function.
BrusselsAges 18–90 - NCT07066475Recruiting
Spinal cord glioma surgery results study
This study is collecting information from patients with spinal cord glioma who are having surgery through a specific surgical approach (dorsolateral sulcus). It aims to learn how well the surgery works and what the recovery looks like over time.
Beijing, Beijing MunicipalityAges 3–75 - NCT06779487Recruiting
Predicting memory changes from brain radiation
This study looks for biomarkers in your blood that might predict how radiation treatment affects brain function. The goal is to understand and possibly reduce cognitive side effects.
Mumbai, MaharashtraAges 5–39 - NCT05929495RecruitingPhase 2
Metformin added to standard treatment for newly diagnosed glioblastoma
This Phase 2 study tests whether adding metformin to the usual treatment for newly diagnosed glioblastoma (GBM) can improve outcomes. It involves taking metformin after surgery along with standard care (the Stupp protocol).
MilanAges 18 years+
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Common questions
- Are there clinical trials for glioma?
- Yes. Clin2 currently lists 331 recruiting glioma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a glioma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a glioma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.