Clinical trials
Heart Failure; With Decompensation clinical trials
Below are recruiting heart failure; with decompensation clinical trials, each written for real people, not researchers. We’re tracking 152 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07407816Recruiting
Supira heart support device for high-risk artery stenting
This trial tests a new device (the Supira system) that helps support your heart's pumping function during and after a high-risk procedure to open blocked coronary arteries. It is for people with heart failure and complex blockages who may need extra circulatory support.
Tbilisi, K'alak'i T'bilisiAges 18–90 - NCT06218199RecruitingPhase 4
Diuretics vs. blood pressure meds for HeartLogic alerts
This trial compares two treatments—diuretics (water pills) and a blood pressure medication called sacubitril/valsartan—to see which works better when your heart device sends an alert. It's for people with a Boston Scientific heart device that has HeartLogic alerting turned on.
Huntsville, AlabamaAges 19 years+ - NCT07830758RecruitingPhase 1
Resmetirom for fatty liver disease with heart failure
This trial tests a drug called resmetirom for people who have both a type of fatty liver disease (MASH) and a type of heart failure (HFpEF). It aims to see if the drug can help both conditions. You may be able to join if you have both conditions and meet certain health criteria.
Peoria, ArizonaAges 18 years+ - NCT06142474RecruitingPhase 3
SGLT2 inhibitors for heart failure patients during ventilator weaning
This trial tests a heart failure medication (SGLT2 inhibitor) to help people with heart failure who are on a breathing machine (ventilator) get better and come off the machine faster. It is for patients with a specific type of heart failure where the heart pumps weakly (EF ≤ 40%).
TaipeiAges 20 years+ - NCT05761067Recruiting
Trial for advanced heart weakness with low pumping ability
This study looks at treatment options for adults with significantly reduced heart pumping strength and extensive coronary artery disease. It may help people who are at higher risk due to widespread blocked heart arteries, but eligibility depends on recent heart events and bleeding risk.
GothenburgAges 18 years+ - NCT07656454RecruitingPhase 1
Comparing two ways to give CDR132L in healthy volunteers
This study measures how well the drug CDR132L enters the blood when injected under the skin, compared to injection into a vein. It is done in healthy volunteers to find the best way to give the drug.
BerlinAges 18–55 - NCT07643818Enrolling by invitationPhase 2
Intravenous iron for heart failure patients with low iron
This study tests whether giving intravenous iron improves symptoms, quality of life, and exercise ability in people with heart failure and low iron levels. Participants will receive iron infusions and be monitored over time to see if their condition improves.
Saint HelierAges 18 years+ - NCT07636343Recruiting
Eccentric Training for Heart Failure Recovery
This trial tests a special type of strength training (eccentric exercise, where muscles lengthen under load) for people with heart failure who have reduced pumping ability. The goal is to improve your exercise capacity and heart function safely.
EdegemAges Any age - NCT05428631Recruiting
Monitoring device tested in severe kidney and heart failure
This study checks how safe a small heart-pressure monitoring device is for people with advanced heart failure and severe kidney problems. It looks at whether doctors can continuously track heart filling/pressure to help manage symptoms and reduce risks.
Nîmes, GardAges 18–85 - NCT07443696RecruitingPhase 2
Heart imaging test to see if bypass surgery could help
This study uses two imaging scans to see if parts of your heart muscle are still alive but not working well. This could help doctors decide if you might benefit from heart bypass surgery.
Beijing, Beijing MunicipalityAges 18–85 - NCT07400042Recruiting
Peripheral vein pressure test for heart failure patients
This study tests if measuring pressure from a vein in the arm can help guide treatment for people hospitalized with worsening heart failure. It aims to understand if this simple procedure could replace or reduce the need for more invasive monitoring.
Milwaukee, WisconsinAges 18 years+ - NCT06714344Recruiting
Heart failure therapy support study
This trial tests a new tool to help doctors better manage heart failure treatment. It may be for patients who need IV diuretics for fluid buildup, either in the hospital or at home to avoid hospitalization.
Graz, StyriaAges 18 years+ - NCT07269366Recruiting
Surgery vs stents for heart disease with weak heart pump
This trial compares two ways to restore blood flow to the heart—bypass surgery (CABG) or stents (PCI)—in people whose heart pumps weakly (LVEF 40% or less). It aims to find which method works better for chest pain or recent heart issues.
GroningenAges 18 years+ - NCT07270536Recruiting
Pacing and heart pressure in HFpEF exercise
This study tests whether a special pacing setting during exercise can help improve heart filling pressures in people with heart failure with preserved ejection fraction (HFpEF) who already have a DDD pacemaker. If you have HFpEF and a pacemaker, you may help researchers find better ways to manage your condition during activity.
HasseltAges 18 years+ - NCT07251361Enrolling by invitation
Exercise program for heart failure with preserved ejection fraction
This study tests whether a special exercise program that combines different types of training (like aerobic, strength, and balance) can improve heart and muscle function, daily abilities, and quality of life in people with heart failure with preserved ejection fraction (HFpEF). You may benefit if your heart failure is stable and you are able to exercise safely.
Pamplona, NavarreAges 18 years+ - NCT07237451Recruiting
Heart and kidney study of SGLT2 inhibitors
This study looks at whether a type of diabetes medicine called SGLT2 inhibitors (also known as flozins) can help protect the heart and kidneys in people with both heart failure with preserved pumping function and moderate chronic kidney disease, with or without diabetes.
IașiAges 18 years+ - NCT07215715Recruiting
Heart ultrasound study for older adults with heart failure
This study uses a special ultrasound to measure heart stiffness in people 60 and older who have heart failure with preserved or mildly reduced pumping function, with or without a condition called ATTR amyloidosis (a protein buildup in the heart). It also includes healthy controls.
Boston, MassachusettsAges 60 years+ - NCT06897410Recruiting
Support program after hospital discharge for heart or lung issues
This program offers extra support—like social and home care help—after you leave the hospital for a heart or lung problem. It's designed for people 65 and older who live in the Sant Jaume de Calella Hospital area.
Calella, BarcelonaAges 65 years+ - NCT06874556Recruiting
Paramedic support for heart failure management
This study tests if paramedics can help manage heart failure at home or in clinic, reducing hospital visits. It may be an option if you need frequent diuretic adjustments or early discharge with monitoring.
Rochester, MinnesotaAges 18 years+ - NCT06779552Recruiting
Study of CardioMEMS System for Heart Failure Patients
This study is looking at how well the CardioMEMS heart monitor works for people with heart failure. The device is already implanted and tracks pressure in your lung artery to help your doctor manage your condition and potentially prevent hospital visits.
Pleasanton, CaliforniaAges 18 years+ - NCT06747429Recruiting
High-fat diet for heart failure metabolism
This trial tests whether a high-fat diet can help change how your heart uses energy, potentially improving heart function in people with non-ischemic heart failure.
ParisAges 18 years+ - NCT06444425Enrolling by invitation
AI test for heart function using ultrasound
This trial uses artificial intelligence to analyze heart ultrasound images. It aims to see if AI can detect heart function better than standard methods. You may be eligible if you are a cardiology patient having an ultrasound and can return for extra blood pressure checks.
Yiwu, ZhejiangAges 18 years+ - NCT06427304Recruiting
Heart scan study for amyloid protein in older adults
This trial is testing older adults with heart failure to see if a heart condition called cardiac amyloidosis (a buildup of abnormal protein in the heart) is present. If you are 80 or older, have been in the hospital for heart failure in the past year, and have a thickened heart wall, you may be able to join.
Paris, IIe-de-FranceAges 80 years+ - NCT06291922Recruiting
Home exercise program for LVAD recovery
This study tests a home exercise program using your smartphone after you get a HeartMate 3™ LVAD. It aims to help you get stronger and recover safely at home.
Detroit, MichiganAges 18 years+
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Common questions
- Are there clinical trials for heart failure; with decompensation?
- Yes. Clin2 currently lists 152 recruiting heart failure; with decompensation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure; with decompensation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure; with decompensation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.