Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 983 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06051058Recruiting
App for managing health after hospital discharge
This study tests a smartphone app designed to help people with multiple health conditions manage their care after leaving the hospital. It may help you feel more supported and avoid confusion during the transition from hospital to home.
Boston, MassachusettsAges 55 years+ - NCT07692256RecruitingPhase 2
Empagliflozin for heart failure in children
This trial tests if empagliflozin, a diabetes medicine that also helps the heart, can improve symptoms in children with heart failure. It may help kids with severe symptoms or high levels of a heart stress marker called BNP.
Cairo, Cairo GovernorateAges 1 month–18 years - NCT06501768RecruitingPhase 1/Phase 2
Genistein for heart failure inflammation
This trial tests a natural substance called genistein (found in soy) to reduce inflammation in people with heart failure. It may help your heart work better and feel better.
LjubljanaAges 40–80 - NCT06541509RecruitingPhase 1/Phase 2
Semaglutide for heart failure in overweight patients
This trial studies whether the drug semaglutide can help people with heart failure who are overweight. It aims to see if the drug improves heart function and symptoms.
Palo Alto, CaliforniaAges 20–80 - NCT06555757Recruiting
Using AI and sound to predict heart failure worsening
This trial uses a smartphone app to record sounds from your chest and breathing. An AI system will analyze these sound patterns to predict when heart failure symptoms might get worse, so you can get help sooner.
Cambridge, CambridgeshireAges 18 years+ - NCT06585761Recruiting
SGLT2 inhibitors for heart failure: effect on inflammation
This trial tests whether a type of diabetes medicine called SGLT2 inhibitors can lower inflammation and stress markers in people with heart failure. It may help reduce damage to the heart and improve symptoms.
Kafr ash ShaykhAges 18–80 - NCT06604468Recruiting
Portable chest device for detecting lung fluid in heart failure
This trial tests a small, portable device worn on the chest that measures changes in fluid levels in your lungs to help detect early signs of fluid buildup (pulmonary congestion). This could help people with heart failure avoid emergency hospital visits.
Montreal, QuebecAges 18 years+ - NCT06650995Recruiting
Ablation and Exercise for Heart Failure with Normal Pumping
This study tests whether a combination of catheter ablation (a procedure to correct irregular heartbeats) and a structured exercise program can improve symptoms and quality of life in people with diastolic heart failure and a recent onset of persistent atrial fibrillation.
MunichAges 18–99 - NCT06653725RecruitingPhase 2
Ketone supplement study for hospitalized heart failure patients
This trial tests if a ketone supplement can help people hospitalized for acute heart failure. The supplement is given orally and aims to support the heart and energy levels during recovery.
AalborgAges 18 years+ - NCT06747689Recruiting
Sleep quality and self-care in heart failure
This study looks at how sleep quality affects the ability of people with heart failure to manage their own health. It aims to find if better sleep leads to better self-care.
IzmirAges 18 years+ - NCT06805253Recruiting
Heart recovery after surgery for leaky aortic valve
This trial studies how well the heart's main pumping chamber (left ventricle) recovers after surgery to fix a leaky aortic valve. It is for people who also have a leaky mitral valve and an enlarged left ventricle, and who are having their first planned valve surgery.
MoscowAges 18 years+ - NCT06809686Recruiting
ECG and patient experience study for heart failure
This study collects detailed ECG data and feedback from people with heart failure to better understand the condition and improve care. It involves noninvasive monitoring and a discussion of your symptoms and daily life.
London, LondonAges 45–80 - NCT06929806RecruitingPhase 3
Iron infusion for iron deficiency with heart failure
This study tests whether giving iron through a vein can help people with heart failure and low iron levels feel better. It compares iron treatment to no iron treatment.
Pasadena, CaliforniaAges 18 years+ - NCT06940544Recruiting
Heart failure screening study for adults 40+
This study is looking for people who may have undiagnosed heart failure. It tests a self-screening method at home to find heart problems earlier.
UppsalaAges 40 years+ - NCT07099885Recruiting
Urine test to guide water pill treatment for heart failure
This study tests a simple urine test to help doctors choose the best dose of water pills (diuretics) for people hospitalized with heart failure and leg swelling. The goal is to relieve congestion faster and more safely.
Wroclaw, DolnosląskieAges 18 years+ - NCT07108231Recruiting
Breathing muscle training for hospitalized heart failure patients
This trial tests whether training the muscles you use to breathe can help people recover while in the hospital for heart failure. If you are stable enough, you may be able to join.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT07201714RecruitingEarly Phase 1
Carnitine supplement for heart failure with kidney issues
This trial tests whether taking carnitine supplements by mouth can help people who have both heart failure and early-to-moderate kidney problems. It's an early-phase study to see if the supplement is safe and works for this group.
London, OntarioAges 18 years+ - NCT07243769Recruiting
Comparing exercise types for heart rehab
This trial compares core, aerobic, and combined exercise in patients doing phase II cardiac rehab. It aims to find which type works best for heart recovery.
TaipeiAges 18 years+ - NCT02638142Recruiting
Testing IV diuretic treatment for sudden worsening heart failure
This trial studies how an IV (into-the-vein) “water pill” (furosemide/loop diuretic) works in people whose heart failure has suddenly gotten worse. It may help doctors find the best way to reduce fluid-related symptoms like breathing trouble and swelling.
Chioggia, VeneziaAges 18 years+ - NCT03008291Recruiting
Heart pacemaker study for slow heartbeats and heart failure
This trial tests how pacing from a specific part of the heart (a “bundle” pacing approach) can affect people with heart failure and/or slow heart rhythms. It may help certain patients whose heart rhythm is too slow or who need a pacemaker and related devices.
Rochester, MinnesotaAges 18 years+ - NCT07402239Recruiting
Heart failure therapy and monitoring device study
This trial tests a device that treats and monitors heart failure. It may help people with chronic heart failure and reduced heart function who still have symptoms despite standard treatments.
Fuzhou, FujianAges 18 years+ - NCT07490054RecruitingPhase 1
Fecal transplant for chronic heart failure
This trial tests whether transferring healthy gut bacteria (fecal microbiota transplant) can help people with chronic heart failure feel better and improve their heart function.
New York, New YorkAges 18 years+ - NCT07552142Recruiting
Heart Failure Check-In: Using Questionnaires to Spot Early Warning Signs
This study asks heart failure patients who recently were hospitalized to answer regular questionnaires about how they're feeling. Researchers want to see if these questions can detect when heart failure is getting worse before a patient needs emergency care.
Moscow, Non-US/Non-CanadianAges 18 years+ - NCT07572032RecruitingPhase 4
Heart failure recovery after valve or coronary surgery
This study tests when to start two heart-protective medications (ARNI and SGLT2 inhibitors) after you've had surgery to fix a valve problem or blocked heart arteries. Researchers want to see if waiting a bit before starting these drugs helps your heart recover better.
Daegu, DaeguAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 983 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.