Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 984 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05558605Recruiting
AI ultrasound guidance for heart risk management
This trial tests whether using an artificial-intelligence (AI) tool during a heart ultrasound can help guide care for people at risk for heart problems. You might benefit if you have symptoms with exercise or heart risk factors, but you do not already have known heart failure or major heart disease.
Alice Springs, Northern TerritoryAges 45 years+ - NCT02820233Recruiting
Study of a heart-signal drug during bypass surgery
This study looks at a treatment that affects signals between heart cells in people with severe coronary artery disease who are scheduled for bypass surgery. The goal is to see if changing these heart-cell signals can improve heart outcomes around the time of surgery.
Portland, MaineAges 18 years+ - NCT06271577Recruiting
Smartphone ECG for heart attack detection
This study tests whether a smartphone can take a 12-lead ECG (a heart tracing) quickly when someone arrives at the ER with chest pain, to help doctors spot a heart attack sooner.
Rochester, MinnesotaAges 18 years+ - NCT07705269Recruiting
High-rate fluid removal for fluid overload in dialysis patients
This trial tests whether a faster rate of fluid removal during dialysis can help hospitalized patients with end-stage kidney disease who have severe fluid buildup. It aims to reduce fluid congestion and improve outcomes.
Monterrey, Nuevo LeónAges 18 years+ - NCT03549559Recruiting
Heart imaging study in healthy people and specific conditions
This study uses heart imaging to look at changes in the heart muscle. It includes healthy volunteers and people with diabetes or aortic stenosis, to understand differences seen on scans.
Boston, MassachusettsAges 18–85 - NCT03793257Recruiting
ECMO patient registry for adults in Australia and New Zealand
This is a research registry for adults who need a breathing and/or heart support machine called ECMO while in the hospital. It collects information to better understand who receives ECMO and how patients do over time.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT05303896Recruiting
Study changes in remodeling heart tissue before transplant
This study looks at how the heart’s structure changes (“remodeling”) in people with heart failure who are being considered for a heart transplant. It may help doctors better understand what is happening in the failing heart and how to treat it.
Oslo, OsloAges 18–100 - NCT05958706Recruiting
Testing how heart cells use fuel in heart failure
This study looks at how the heart uses energy fuel in people with heart failure, including those with type 2 diabetes. It may help researchers understand what’s going on inside the heart and how it could be treated in the future.
DüsseldorfAges 20–85 - NCT06620705Recruiting
Pacing options for AF with low heart function
This trial compares two types of pacing for people with permanent atrial fibrillation (AF) and a weak heart pump (ejection fraction less than 50%). It tests whether pacing the left bundle branch area works as well as or better than standard biventricular pacing to improve heart function.
Aarhus N, Aarhus NAges 18 years+ - NCT06838611Recruiting
Study of patients with severe tricuspid regurgitation
This study is collecting information about people with severe tricuspid regurgitation (a leaky heart valve) who are having a catheter-based repair. The goal is to better understand these patients and how well the procedure works for them.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07339007Enrolling by invitation
Validating a heart ultrasound training program for family doctors
This study tests whether a training program helps family doctors use a focused heart ultrasound (FoCUS) to assess patients. If you need a heart ultrasound as part of your regular care, you may be able to join.
Barcelona, CataloniaAges 15 years+ - NCT06954792Enrolling by invitation
Studying heart changes after tricuspid valve replacement
This study looks at how the heart adjusts after a procedure to replace the tricuspid valve (the valve between the right upper and lower heart chambers). It focuses on patients who need medication to support their blood pressure within 24 hours after the procedure, to better understand and manage this unstable period.
New York, New YorkAges 18 years+ - NCT06690684Enrolling by invitation
Finding new blood markers for heart disease
This study is looking for people who have had a heart attack or have heart failure to discover new markers in your blood that could help doctors better understand and treat heart disease. By collecting samples and health data, researchers hope to find clues that improve care for future patients.
Shanghai, Jing 'an DistrictAges 30 years+ - NCT05775354Enrolling by invitation
Early heart disease check-in in adults age 50–80
This study aims to improve early detection of heart and blood vessel problems by adding further research after routine care. It may help you by making sure your heart risk is monitored more closely, if you’re eligible and agree to the additional steps.
UtrechtAges 50–80 - NCT04471129Recruiting
Noninvasive breathing support after heart surgery to protect heart function
This study tests whether two noninvasive breathing/oxygen treatments after cardiac surgery help improve heart function. It may benefit people with weak pumping function who are recovering in the hospital and can safely use these devices.
RouenAges 18 years+ - NCT04180085RecruitingPhase 2
Belatacept to protect kidneys in heart transplant patients
This trial studies whether belatacept can be used after a heart transplant to help protect kidney function over time. It focuses on people who already have (or are at risk for) worsening kidney function after transplant, while avoiding those with certain infections or rejection concerns.
BordeauxAges 18 years+ - NCT04201015RecruitingPhase 2/Phase 3
Testing exercise pacing to improve heart pumping
This trial tests whether “pacing” your exercise (doing it at the right rate) can improve how strongly your heart pumps. It’s for people with heart failure who have a pacemaker and can safely do an exercise test.
LeedsAges 18 years+ - NCT05641662Recruiting
Video games that get you moving for heart failure inactivity
This study tests whether playing “exergames” (motion-based video games) can help people with heart failure who are mostly inactive spend less time sitting. It checks whether the games are safe and practical and whether they can improve activity over time.
PortoAges 18 years+ - NCT05696522Recruiting
Radiation to treat hard-to-control dangerous heart rhythm
This trial tests a focused type of radiation to treat ventricular tachycardia (VT) that keeps coming back despite other treatments. It may help people who cannot (or do not want to) have the usual catheter procedure to fix the rhythm.
LondonAges 18–85 - NCT05972070Recruiting
Telemedicine home cardiac rehab after heart procedure
This trial studies whether cardiac rehabilitation done at home, with help from telemedicine, is safe and helps you stick with the program after a recent heart procedure. It may help you recover with more convenience while still improving heart-related fitness and adherence.
Brookfield, ConnecticutAges 18 years+ - NCT06049420Recruiting
Lifestyle medicine for rural patients with chronic disease
This trial tests whether exercise therapy can help people with two or more chronic conditions like obesity, diabetes, or heart disease. It's designed for rural patients and requires a referral from your doctor.
Lewisburg, West VirginiaAges 18–64 - NCT06307262Recruiting
European registry for tricuspid valve repair
This trial is a registry that collects information on patients who have had a minimally invasive procedure to fix a leaky tricuspid valve. By joining, you help doctors learn more about how well these devices work over time.
Munich, BavariaAges 18 years+ - NCT06634121Recruiting
Comparing MitraClip and PASCAL for mitral valve repair
This trial compares two devices (MitraClip and PASCAL) for repairing a leaky mitral valve (mitral regurgitation). The goal is to see which device works better in a wide range of patients who need this type of repair.
Munich, BavariaAges 18 years+ - NCT07343895Recruiting
Atrial fibrillation screening in people with high NT-proBNP
This study is checking people over 40 who have a higher-than-average heart stress marker (NT-proBNP) to see if they have undiagnosed atrial fibrillation. You'll use a smartphone to track your heart rhythm at home.
TromsøAges 40 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 984 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.