Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 989 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04145024Recruiting
Pulmonary hypertension registry and blood sample biobank
This study keeps a health registry and biobank for people diagnosed with pulmonary hypertension using a specific heart test. It helps researchers better understand the condition and may improve future care.
GiessenAges Any age - NCT04160533Recruiting
Registry for people diagnosed with high blood pressure
This registry collects information from people who have been diagnosed with high blood pressure. It may help researchers better understand who has it and how it’s managed in real life.
Moscow, Moscow OblastAges 18–99 - NCT04212455Recruiting
Study of blood tests linked to high blood pressure
This study looks at whether certain blood markers can help explain or predict high blood pressure in adults. It may help researchers understand hypertension better, which could support future prevention or treatment.
Guangzhou, GuangdongAges 18 years+ - NCT04356326RecruitingPhase 3
Aspirin to prevent complications in pregnancy with chronic high blood pressure
This trial studies whether taking acetyl salicylic acid (aspirin) during pregnancy can reduce problems caused by chronic high blood pressure. It focuses on pregnant people already known to have high blood pressure before or early in pregnancy.
BordeauxAges 18 years+ - NCT04578301Recruiting
Predicting who develops serious liver worsening after surgery
This study looks at your liver health before and after surgery to predict the risk of “acute-on-chronic liver failure,” which means a sudden worsening of liver function on top of an existing liver condition. If you qualify, your doctors may use study data to better identify who needs closer monitoring after surgery.
BonnAges 18 years+ - NCT04654650Recruiting
Study of adults with pulmonary hypertension for long-term data
This study follows adults with pulmonary hypertension over the long term and collects information (and possibly samples) to better understand how the condition changes over time. It may help researchers learn what factors affect outcomes, which can improve care in the future.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT04690660Recruiting
Study of high blood pressure after pregnancy
This study follows people who had high blood pressure during pregnancy and/or in the first two weeks after delivery. The goal is to better understand postpartum hypertension so care can be improved for mothers at higher risk.
BaselAges 18 years+ - NCT04720456RecruitingPhase 2
Ultrasound test study for high pressure in liver veins in kids
This Phase 2 trial looks at a special ultrasound approach to better understand and measure portal hypertension—high pressure in the liver’s vein system—in children with long-term (chronic) liver disease. The results may help doctors track this condition more accurately and safely.
Philadelphia, PennsylvaniaAges 6–21 - NCT04753840Recruiting
Remote arm conditioning and mindfulness for mild high blood pressure
This trial studies whether doing “remote ischemic preconditioning” (repeated brief conditioning of a limb) and mindfulness helps people with mild high blood pressure over the long term. It may help lower blood pressure and improve heart-related health, if you can safely do the required activities.
Zhengzhou, HenanAges 18–80 - NCT04755764Recruiting
Compare blood-pressure medicines in early pregnancy
This trial tests how three common blood-pressure medicines (labetalol, atenolol, and nifedipine) affect blood flow in early pregnancy. It may help doctors choose the safest, most effective option for pregnant people with high blood pressure.
Huntington, West VirginiaAges 18–45 - NCT04756076Recruiting
Study heavy metal levels in pulmonary hypertension patients
This study looks at whether heavy metals in the body—and an imbalance of important minerals—are different in people with pulmonary arterial hypertension. It may help researchers understand possible causes and targets for future treatments.
Louisville, KentuckyAges 18 years+ - NCT04778046RecruitingPhase 2
Study lung pressure treatment for people waiting for transplant
This Phase 2 trial is for adults with pulmonary hypertension who are on the lung transplant waiting list at Duke. It aims to test whether the study treatment can improve lung pressure and related health outcomes, while using things like MRI to monitor changes.
Durham, North CarolinaAges 18 years+ - NCT04838678RecruitingEarly Phase 1
Testing a new blood-pressure approach in obesity-related hypertension
This early-stage study tests a new way to help control high blood pressure that is linked to obesity. It may help people whose blood pressure is high based on a 24-hour blood pressure monitor.
Dallas, TexasAges 18–55 - NCT04898114RecruitingPhase 1/Phase 2
Inhaled magnesium and sildenafil for newborn lung blood pressure
This study tests whether breathing in magnesium sulfate and giving sildenafil can improve breathing and lung blood vessel pressure in newborns with persistent pulmonary hypertension. It may help newborns who are having trouble oxygenating despite being on a ventilator.
SohagAges 6 hours–3 days - NCT05798923RecruitingPhase 2
LAM-001 for lung scarring with high blood pressure
This trial tests a new medication called LAM-001 for people with high blood pressure in the lungs caused by lung scarring. It aims to see if it can improve symptoms and help you feel better.
Tucson, ArizonaAges 18–80 - NCT04974138RecruitingPhase 4
Preventing first stroke in people with high-risk blood pressure
This trial tests whether a study medicine regimen can help prevent a first stroke in people with hard-to-control “high homocysteine” risk factors linked to a specific gene type. You may qualify if you have certain blood pressure levels, a specific MTHFR gene result, and related blood test findings.
Bengbu, AnhuiAges 45–74 - NCT04974151RecruitingPhase 4
Prevention trial for stroke risk in people with high blood pressure
This trial tests an approach to prevent first-time stroke and heart problems in people with high blood pressure who also have a specific genetic test result (MTHFR 677 TT). It may help by lowering risk before a first stroke happens.
Bengbu, AnhuiAges 45–74 - NCT05039684Recruiting
Testing eye-surface inflammation in glaucoma or high eye pressure
This study measures inflammation markers on the eye surface in people with primary open-angle glaucoma or ocular hypertension who use certain glaucoma drops. The results may help doctors understand how these drops affect the eye and inflammation.
ValladolidAges 18–99 - NCT05156385Recruiting
Study of sexual problems in women with treated high blood pressure
This study looks at sexual dysfunction (sexual problems) in women who are being treated for high blood pressure. It may help researchers understand what causes these issues and what could improve them.
Toulouse, CHU de ToulouseAges 18 years+ - NCT05166954Recruiting
Bariatric surgery and heart function in people with high blood pressure
This study looks at whether bariatric (weight-loss) surgery improves heart function in people who have high blood pressure. You may be able to join if you’re already a bariatric surgery patient at the study hospital and meet the health and medication criteria.
Beijing, Beijing MunicipalityAges 17–70 - NCT05179876RecruitingPhase 3
Treatment access study for pulmonary hypertension when no other option
This Phase 3 study continues treatment for people with pulmonary hypertension who finished an earlier parent study and have no other approved treatment option. It tests whether continuing their current medicine can help them keep getting benefit and stay safe.
MinskAges 2 years+ - NCT05184933Recruiting
Study sleep timing and blood pressure patterns in adults
This study looks at how your sleep schedule and body clock relate to blood pressure control. You may be asked to follow a study plan that helps researchers understand what sleep and daily timing changes do to hypertension.
Portland, OregonAges 25–64 - NCT05234788Recruiting
Radial-access kidney nerve procedure for hard-to-control high blood pressure
This trial tests a procedure that uses a catheter through the wrist or thigh to quiet overactive nerves in the kidney artery. It aims to lower blood pressure in people whose high blood pressure stays uncontrolled despite using multiple blood pressure medicines.
BordeauxAges 18–75 - NCT05309460RecruitingPhase 4
Labetalol or nifedipine to treat postpartum high blood pressure
This study compares two common blood pressure medicines—labetalol and nifedipine—to control high blood pressure after childbirth. It may help you and your care team find the safest way to bring your blood pressure back to normal after delivery.
Omaha, NebraskaAges 19 years+
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 989 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.