Clinical trials
Insulin Resistance clinical trials
Below are recruiting insulin resistance clinical trials, each written for real people, not researchers. We’re tracking 125 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07102797Recruiting
ActiveGirls: Activity, hormones, and diabetes risk in young girls
This study looks at how physical activity and hormone health affect diabetes risk in young girls. It is for girls ages 8 to 12 who are at risk for PCOS (a hormone condition) and insulin resistance, and who have not yet started their period.
Somerville, MassachusettsAges 8 years+ - NCT07094776Enrolling by invitation
MG53 protein levels in women with PCOS
This study measures a protein called MG53 in the blood of women with and without PCOS to see if it could be a marker for the condition. If you have PCOS and are not taking certain medications, you may be able to join and help researchers better understand the disease.
Gaziosmanpaşa, IstanbulAges 18–45 - NCT06959043Recruiting
Diet and exercise for type 2 diabetes
This study tests if a plant-based diet and exercise program can improve blood sugar control in people with type 2 diabetes. Participants will live in a hospital for 4 weeks to follow the program closely.
São Paulo, São PauloAges 45–70 - NCT07073781Recruiting
Probiotics for Brain & Blood Sugar in Overweight Young Adults
This study tests whether taking a probiotic (a 'good bacteria' supplement) can help brain function (thinking, memory) and improve blood sugar control in overweight adults who have higher-than-normal blood sugar. If you're between 18-40, overweight, and don't have diabetes, you may be able to join.
Leeds, Greater ManchesterAges 18–40 - NCT06542718Recruiting
Studying glucose patterns in Asian women with gestational diabetes
This study monitors blood sugar levels during pregnancy in overweight Asian women to better understand gestational diabetes. It uses a continuous glucose monitor to track patterns and may help improve care for mothers and babies.
SingaporeAges 21–45 - NCT04934228RecruitingPhase 1
Study targeting inflammation in people with obesity and high blood pressure
This Phase 1 study looks at a treatment aimed at reducing “inflammation patterns” that are common in obesity and insulin resistance. If you meet specific health and lab criteria, you may be asked to visit a research lab and provide blood samples to see how the treatment affects your body.
Kansas City, KansasAges 18–79 - NCT04715022RecruitingPhase 1/Phase 2
Vitamin C study for insulin resistance in obesity
This early-stage study tests whether vitamin C (and possibly how your body uses it) affects blood vessel function in people with obesity and insulin resistance. You may be asked to stop certain supplements before starting so researchers can measure the effect more clearly.
Kansas City, KansasAges 35–65 - NCT06867198Recruiting
Peanuts for heart, brain, and gut health
This study tests whether eating peanuts can improve health markers like blood sugar, brain function, and digestion in adults with prediabetes (higher than normal blood sugar levels). You may qualify if you are between 20-59 years old, have prediabetes, and a BMI in the overweight to obese range.
Atlanta, GeorgiaAges 20–59 - NCT06826807Enrolling by invitation
Lifestyle change study for fatty liver disease
This study tests whether adding a liver stiffness measurement to a lifestyle program helps people with MASLD (a type of fatty liver disease) improve their liver health. It is designed for people who have fatty liver and at least one sign of metabolic syndrome, like high blood pressure or diabetes.
Bangkoknoi, BangkokAges 18–80 - NCT06820658Recruiting
Comparing muscle response in active and inactive older adults
This study looks at how muscles respond to exercise in people aged 60 to 85. You will be asked to do some exercises so researchers can measure how your nerves and muscles work together.
Rochester, MinnesotaAges 60–85 - NCT06770660Recruiting
Remote exercise for teen fitness
This trial tests whether exercising at home through video calls can improve heart and lung fitness in teenagers aged 12 to 17. It might be a convenient way to stay active if you cannot get to a gym or sports club.
SingaporeAges 12–18 - NCT06768827Recruiting
Obesity mechanisms study for teens
This study looks at how bodies process food to understand obesity in teenagers. It may help find new ways to prevent or treat obesity.
New Haven, ConnecticutAges 15–22 - NCT06763328RecruitingPhase 3
Metformin for insulin resistance after breast cancer chemo
This study tests if metformin, a common diabetes medicine, can help reduce insulin resistance in women who finished chemotherapy for early-stage breast cancer. It aims to improve long-term health and prevent future problems.
Duarte, CaliforniaAges 18 years+ - NCT06735651Recruiting
Wild blueberries for gut, brain, and heart health in prediabetes
This study looks at whether eating wild blueberries can improve your gut health, brain function, and heart health if you have prediabetes. It may help lower your blood sugar and reduce your risk for diabetes and heart disease.
Atlanta, GeorgiaAges 20–65 - NCT06657209RecruitingPhase 4
Comparing diabetes treatments for people with normal weight
This study tests two medications—pioglitazone (a pill) and tirzepatide (an injection)—in people with type 2 diabetes who have a normal body weight. It aims to find which treatment works better for this specific group.
Palo Alto, CaliforniaAges 30–70 - NCT06633380Recruiting
Different physical activity strategies for breast cancer survivors
This study tests different ways to add physical activity into your daily routine to help manage side effects from breast cancer treatment. The goal is to see if simple, practical strategies can improve your health and well-being while you are on aromatase inhibitors.
Toronto, OntarioAges Any age - NCT06545721Recruiting
Weight changes and hormone health in PCOS
This study looks at how weight changes affect hormone levels and insulin resistance in women with PCOS. It may help understand if weight cycling is harmful or helpful.
Beijing, Beijing MunicipalityAges 18–45 - NCT06334666Enrolling by invitation
Step counting for fatty liver disease management
This trial tests if using a pedometer to track daily steps can help people with a type of fatty liver disease (called MASLD) become more active and improve their health. It may be a good fit if you are not already very active and want to try a simple way to manage your condition.
Bangkoknoi, BangkokAges 18 years+ - NCT05958706Recruiting
Testing how heart cells use fuel in heart failure
This study looks at how the heart uses energy fuel in people with heart failure, including those with type 2 diabetes. It may help researchers understand what’s going on inside the heart and how it could be treated in the future.
DüsseldorfAges 20–85 - NCT05543083Recruiting
Therapy plus exercise for teens at risk of type 2 diabetes
This trial tests whether a combination of coaching (cognitive-behavioral therapy) and exercise can improve mood and help teens who are at higher risk for type 2 diabetes. It may be especially helpful if you’re dealing with depression symptoms and a family history of type 2 diabetes.
Aurora, ColoradoAges 12–17 - NCT05277558Recruiting
MRI and brain testing in teens at risk for type 2 diabetes
This study looks at brain health in teens with normal weight, overweight, or obesity who are at risk for type 2 diabetes. It may help researchers understand how weight and diabetes risk affect the brain, using MRI scans and learning/memory tests.
St Louis, MissouriAges 12–17 - NCT04984226RecruitingPhase 2
Sodium bicarbonate for kidney disease energy and acidity
This trial studies whether taking sodium bicarbonate changes “energy” in cells and improves metabolic acidosis (an acid build-up) in people with moderate-to-severe chronic kidney disease. You may be able to join if your kidney function and blood bicarbonate levels fit their targets and you meet safety rules.
Sacramento, CaliforniaAges 21–85 - NCT04791371Recruiting
Study how fitness and insulin resistance relate to diabetes
This study looks at how low physical activity, insulin resistance in small blood vessels, and cardiorespiratory fitness connect to diabetes and blood sugar control. You may be eligible if you are generally sedentary and fit within the weight range, and if you do not have certain heart, lung, nerve, or medication factors.
Aurora, ColoradoAges 30–55 - NCT04812314Recruiting
Study how exercise changes body fat and metabolism
This study looks at how starting exercise changes the structure and function of body fat. It may help you understand how exercise affects things like cholesterol and blood sugar, even if you’re not currently exercising regularly.
Ann Arbor, MichiganAges 18–40
Hear when a new Insulin Resistance trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for insulin resistance?
- Yes. Clin2 currently lists 125 recruiting insulin resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a insulin resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a insulin resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.