Clinical trials
Ischemic clinical trials
Below are recruiting ischemic clinical trials, each written for real people, not researchers. We’re tracking 814 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05971446Recruiting
Healthy Little Eyes study for newborn vision and brain health
This study looks at eye and vision outcomes in babies who have had lack of oxygen around birth (HIE) and also compares them with healthy “well babies.” It may help doctors better understand how HIE affects the eyes and what to watch for over time.
Madison, WisconsinAges Up to 3 years - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Birmingham, AlabamaAges 18 years+ - NCT05948566RecruitingPhase 2
Improving response to stroke treatment with an antibody drug
This Phase 2 trial tests an antibody treatment (TS23) given to people with a suspected acute ischemic stroke to improve how well they respond to stroke care. You may qualify if your stroke scan shows the right pattern of injured brain tissue and if the study drug can be given within a short time window after symptoms start.
Birmingham, AlabamaAges 18 years+ - NCT05911568Recruiting
Clot-removal treatment for stroke patients with existing disability
This trial studies whether an endovascular (catheter-based) procedure to treat a certain type of blocked artery can improve outcomes for people who already had trouble functioning before their stroke. You may be considered if your stroke is confirmed early and your scans show the right type and location of blockage.
Birmingham, AlabamaAges 18 years+ - NCT05884762Recruiting
Brain training rehab for arm recovery after a recent stroke
This trial tests an upper-limb (arm/hand) rehabilitation program guided by brain activity signals, started soon after a stroke. It may help people with early incomplete arm recovery improve hand and arm function.
RennesAges 18–80 - NCT05897645Recruiting
MRI study of artery plaque after recent stroke
This trial uses special brain MRI to look closely at plaque in certain brain arteries after an ischemic stroke (when a blood vessel is blocked). It may help researchers better understand which plaques are most dangerous soon after stroke.
ShenyangAges 40 years+ - NCT05892510RecruitingPhase 2/Phase 3
Tenecteplase after clot removal for no-reflow stroke
This trial tests whether giving tenecteplase directly into the brain artery after a thrombectomy can improve outcomes when blood flow doesn’t fully return (“no-reflow”) in an emergency stroke. It may help some people by reducing ongoing clot-related blockage after the main clot is removed.
Gold Coast, QueenslandAges 18 years+ - NCT05903560Recruiting
Arm versus leg access for clot removal in basilar stroke
This trial compares doing a clot-removal procedure through the arm artery versus the leg artery for an emergency stroke caused by a blocked basilar artery. It aims to see which access route is safer and more effective for restoring blood flow when time is critical.
Nanjing, JiangsuAges 18 years+ - NCT05885932Recruiting
Stent treatment versus medicines for blocked neck artery
This study compares a drug-coated stent placed in a neck (vertebral) artery versus best medical treatment with medicines and risk-factor control. It aims to reduce problems caused by a badly narrowed artery after recent stroke-like symptoms.
BeijingAges 18 years+ - NCT05851391RecruitingPhase 2
Test drug treatment to stop hard-to-control seizures after cardiac arrest
This Phase 2 trial tests a medication strategy to stop “refractory status epilepticus,” a severe seizure condition that can happen after a cardiac arrest. It may help by reducing ongoing seizure activity after return of circulation in the ICU.
San Francisco, CaliforniaAges 18 years+ - NCT05867381Recruiting
Air purifier use to slow heart artery plaque in older adults
This trial tests whether using indoor air filtration at home can slow the progression of heart artery plaque-related problems in people with a past history of ischemic heart disease. It may help by improving indoor air quality, which the study links to inflammation in the body.
Los Angeles, CaliforniaAges 65–84 - NCT05873881RecruitingPhase 3
Colchicine and vitamin B1 for ischemic heart failure
This study tests whether colchicine and thiamine (vitamin B1) can improve outcomes in people with heart failure caused by blocked or narrowed heart arteries. It’s mainly for people with moderate-to-severe symptoms and reduced heart pumping ability.
Hamilton, OntarioAges 45 years+ - NCT05871606RecruitingPhase 1
Breathing nitric oxide during clot-removal for stroke
This Phase 1 study tests whether inhaled nitric oxide (a gas breathed through a ventilator) can improve outcomes in people having a specific kind of emergency stroke procedure to remove a clot from the brain. It focuses on patients who need general anesthesia for the clot-removal procedure and have imaging results that suggest salvageable brain tissue.
Charlotte, North CarolinaAges 18–80 - NCT05832762Recruiting
Clot-buster procedure for blocked neck artery stroke
This trial studies whether an emergency clot-removal procedure through the blood vessels (endovascular treatment) helps people who have a stroke caused by a blocked internal carotid artery in the neck. It compares outcomes in patients treated urgently when imaging shows the blockage is likely the main cause.
Montpellier, FanceAges 18 years+ - NCT05836610RecruitingPhase 4
Testing hydrocortisone dosing during newborn cooling
This Phase 4 trial studies the best way to give hydrocortisone (a steroid medicine) to newborns who are being cooled for a specific kind of birth-related lack of oxygen. It’s for babies who have low blood pressure during cooling, aiming to improve their stability while they receive standard treatment.
Budapest, Pest CountyAges Up to 3 days - NCT05363397RecruitingPhase 2
Adjunctive TBO-309 added to stroke clot removal treatment safety
This Phase 2 trial studies whether adding TBO-309 to standard emergency treatment for acute ischemic stroke is safe and tolerable. It may help researchers see if the added drug can be given without causing excessive side effects alongside clot-busting and/or clot-removal procedures.
Camperdown, New South WalesAges 18 years+ - NCT05786417RecruitingPhase 4
Medication comparison for older adults with stable heart pain
This trial tests which heart medications work best for older adults who have stable angina (predictable chest pain) and multiple other long-term health problems. You may be asked to start or adjust medications and attend regular follow-up visits to see which approach controls symptoms and outcomes.
New Haven, ConnecticutAges 65 years+ - NCT05795842Recruiting
Detecting atrial fibrillation after stroke using a wrist monitor
This study checks whether a special wrist device can detect an irregular heartbeat (atrial fibrillation) in people who recently had a stroke with an unclear cause. It may help doctors find the cause earlier and tailor follow-up care.
Atlanta, GeorgiaAges 55 years+ - NCT05761483Recruiting
Endoscopic treatment for bile duct narrowing after liver transplant
This trial tests an endoscopic (camera-based) approach to treat bile duct narrowing that happens after a liver transplant. It may help improve bile flow and liver blood test results when the narrowing is in the bile duct area near where the liver’s bile ducts split.
Roma, RMAges 18 years+ - NCT05762432Recruiting
Wound dressing study for certain diabetic foot ulcers
This study looks at a specific wound dressing in people with a non-infected diabetic foot ulcer that has nerve pain (neuropathic), poor blood flow (ischemic), or both. It may help you heal the ulcer and improve how the wound looks and progresses.
Airdrie, North LanarkshireAges 18 years+ - NCT05712395Recruiting
Pain-free exercise program for people with leg artery disease
This trial tests a new kind of exercise that is meant to be non-ischemic (not reduce blood flow) and pain-free, to see if it helps people with peripheral artery disease (PAD) who get leg pain when walking. You may be eligible if you have PAD confirmed by specific treadmill and blood-pressure measurements and meet the exercise and health safety requirements.
Oklahoma City, OklahomaAges 40 years+ - NCT05714618Recruiting
Heart inflammation after stroke
This study uses a special heart MRI to look for inflammation after a stroke. It aims to understand if the brain injury affects the heart, which could lead to better care.
London, OntarioAges 18 years+ - NCT05694663Recruiting
Vagus nerve stimulation to aid stroke recovery
This registry looks at people with a prior ischemic stroke to see how a device that stimulates the vagus nerve may support arm recovery. If you are planning to get the implant and can follow the program steps, your information may be followed to track progress and safety.
New York, New YorkAges 18 years+ - NCT05697575Recruiting
Staphylokinase during stroke blood-flow treatment
This trial studies using a medication called non-immunogenic staphylokinase as part of standard clot-busting treatment for an acute ischemic stroke. It may help clinicians improve blood flow after the stroke using an approach designed to be less likely to trigger immune reactions.
Saint PetersburgAges 18–85
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Common questions
- Are there clinical trials for ischemic?
- Yes. Clin2 currently lists 814 recruiting ischemic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ischemic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ischemic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.