Clinical trials
Knee clinical trials
Below are recruiting knee clinical trials, each written for real people, not researchers. We’re tracking 832 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07424066Recruiting
Knee vibration therapy to improve movement and sensation
This trial tests if gentle vibrations on knee muscles can improve how your brain senses knee movement, which may help you move better. It is for healthy adults who want to see if this non-invasive treatment boosts motor performance.
Milan, MilanAges 18 years+ - NCT07120191Recruiting
My Connect Post-Op study for joint replacement patients
This trial tests a smartphone tool to help communicate with your care team after knee or hip replacement surgery. It aims to improve your recovery experience.
Wichita, KansasAges 22–80 - NCT05806021RecruitingPhase 4
Tested different cortisone doses for knee osteoarthritis pain
This trial compares different doses of injected cortisone (triamcinolone) directly into the knee to see which dose helps knee osteoarthritis pain most. You may be enrolled in a group receiving a 5 mg, 10 mg, or 40 mg dose if you meet the study’s knee and health requirements.
Montreal, QuebecAges 50 years+ - NCT07023185Recruiting
Cold and compression after knee replacement
This study will test if adding cold and compression therapy after knee replacement surgery can help with pain, swelling, and recovery. You may qualify if you are 50 or older and having a knee replacement with a specific surgeon.
New Orleans, LouisianaAges 50 years+ - NCT07394582Recruiting
Pre-surgery optimization for hip or knee replacement
This trial tests a program to improve your health before hip or knee replacement surgery. It aims to help you recover better and reduce risks.
Innsbruck, TyrolAges 18–99 - NCT07384689Recruiting
Study of leg tissue in non-traumatic amputation patients
This study looks at the tissue environment in the legs of patients who need amputation due to non-traumatic causes, like poor blood flow or infection. Understanding the tissue better might help improve healing for future patients.
Aarhus NAges 18 years+ - NCT05824845Recruiting
Join a study collecting information for hip or knee replacement care
This study asks people in the UK who are getting their first hip or knee replacement to answer questionnaires and let researchers use linked health data. The goal is to improve understanding of outcomes and help set up future studies for better care.
AshingtonAges 18 years+ - NCT07356323Recruiting
Study on antibacterial drape for hip or knee replacement
This trial tests if a special antibacterial drape reduces contamination during hip or knee replacement surgery. The drape is placed over the skin to help prevent infection.
Fishers, IndianaAges 22 years+ - NCT05685706Recruiting
Study of spine alignment after hip or knee replacement
This study looks at how the alignment of your spine relates to your walking and posture after hip or knee replacement surgery for wear-and-tear arthritis. It may help doctors better understand how to monitor recovery and long-term function.
Taichung, North DistrictAges Any age - NCT07333560Recruiting
Predicting recovery after hip or knee replacement
This study is developing a tool that uses machine learning to predict how well you will recover after hip or knee replacement surgery. It aims to help doctors create better recovery plans for people like you.
BolognaAges 18 years+ - NCT07313020Enrolling by invitationEarly Phase 1
Handheld imaging to track stem cells in knee osteoarthritis
This trial tests a new handheld imaging device (MPI) to track stem cells injected into the knee. It aims to see if the device can safely monitor how the stem cells move and work in people with knee osteoarthritis.
Haikou, HainanAges 18–75 - NCT06800079Recruiting
Elastic band training for knee strength in female soccer players
This trial tests whether elastic band exercises can improve knee strength and performance in female soccer players. If you play on a U-15, U-19, or senior women's team and compete in a district or national championship, you may be able to join.
Maia, Porto DistrictAges Any age - NCT06939491Enrolling by invitation
Ultrasound-guided electrolysis vs. sham for patellar tendon pain
This trial tests whether a treatment called ultrasound-guided electrolysis therapy can reduce pain and improve tendon health in people with patellar tendinopathy (knee tendon pain). It compares the real treatment to a sham (fake) treatment to see if it works better.
Bremen, Free Hanseatic City of BremenAges 18–59 - NCT07282782RecruitingPhase 4
Vancomycin for knee replacement surgery
This trial is testing the antibiotic vancomycin to prevent infections after total knee replacement. It may help if you are having your first knee replacement and are not severely overweight or diabetic.
San Diego, CaliforniaAges 18 years+ - NCT06962046Recruiting
Can virtual reality improve knee replacement surgery results?
This trial tests if using virtual reality (VR) during knee replacement surgery can help improve your recovery. You wear a VR headset during the procedure to relax and distract you, which may lead to better outcomes.
BelfastAges 18–100 - NCT07213622Enrolling by invitation
Smart glasses for numbing nerve block during knee replacement
This study tests if using smart glasses (like high-tech glasses that show a video) can help doctors give a more accurate numbing injection (nerve block) to the saphenous nerve for knee replacement surgery. The goal is to improve pain control after surgery.
Cleveland, OhioAges 18 years+ - NCT06532929Recruiting
Recovery after sports surgery with Teknimed products
This study is checking how well people recover after sports surgery using Teknimed products. It is for patients who had or will have a surgery with these products, and aims to see how the products perform in real life.
Aubenas, ArdècheAges 18 years+ - NCT06849934Enrolling by invitation
Testing software for knee movement in below-knee amputees
This study tests whether a computer program called Kinovea can accurately measure how your knee moves while walking. If you have a below-knee amputation, use a prosthetic, and meet a few health criteria, you may be able to help improve how amputees are fitted and trained.
AnkaraAges 18–65 - NCT07131579Enrolling by invitation
Dexmedetomidine via IV for knee surgery pain
This trial tests adding a medicine called dexmedetomidine to the numbing IV used during knee surgery. It aims to see if it provides better pain relief after surgery under spinal anesthesia.
Al MansurahAges 18–60 - NCT06563843Recruiting
Study of VRAS robot for knee replacement surgery
This study looks at how surgeons use the Velys Robot-Assisted Solution (VRAS) during total knee replacement. It aims to improve surgical processes and outcomes.
Nottingham, NG5 8RXAges 18–100 - NCT06563531Recruiting
Do compression stockings help after hip or knee replacement?
This trial looks at whether compression stockings are still needed for people who have a new hip or knee joint and are following a modern "fast-track" recovery program. It aims to find out if these stockings are necessary to prevent blood clots when people are up and moving quickly after surgery.
BrestAges 18 years+ - NCT07746284Enrolling by invitation
Understanding knee osteoarthritis through computer modeling
This study looks at how knee osteoarthritis pain works and aims to build a computer model to better understand it. By joining, you may help doctors improve future treatments for chronic knee pain.
Herndon, VirginiaAges 18–99 - NCT06368700Recruiting
Testing a new knee cartilage implant (HYALEX)
This study is testing a new implant called HYALEX to repair cartilage damage in the knee. It may help people with painful knee cartilage defects that haven't gotten better with other treatments like physical therapy or injections.
La Mesa, CaliforniaAges 22–70 - NCT06871098Recruiting
Improving hip hinge movement and confidence
This study looks at how to improve your hip hinge movement (bending forward from the hips) and build confidence in doing it safely. It’s for healthy adults without any pain or injuries in the lower body.
Orlando, FloridaAges 18–50
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Common questions
- Are there clinical trials for knee?
- Yes. Clin2 currently lists 832 recruiting knee studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a knee trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a knee trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.