Clinical trials
Liver Fat clinical trials
Below are recruiting liver fat clinical trials, each written for real people, not researchers. We’re tracking 35 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05644717RecruitingPhase 4
Testing erugliflozin for fatty liver and diabetes control
This trial studies whether erugliflozin can reduce liver fat and liver scarring (fibrosis) while also improving blood sugar in people with type 2 diabetes and fatty liver disease (NASH/NAFLD). It’s designed for people who haven’t used certain diabetes medicines like SGLT2 inhibitors or insulin before.
Peshawar, KPKAges 18–65 - NCT07122700Recruiting
Better tests for fatty liver disease in people with metabolic issues
This study compares new, non-invasive tests to standard liver biopsy for diagnosing fatty liver disease in people with type 2 diabetes or other signs of metabolic syndrome. It aims to see if these simpler tests can replace biopsies.
Miami, FloridaAges 18–75 - NCT06138821Recruiting
Endoscopic sleeve gastroplasty for obesity and MASH
This study tests if a procedure called endoscopic sleeve gastroplasty helps people with obesity and a liver condition called MASH lose weight and improve their liver health. It might be an option if you have both obesity and MASH and haven't had weight-loss surgery before.
Boston, MassachusettsAges 18 years+ - NCT05962190Recruiting
Short-term extra fat intake to study liver metabolism
This study tests what happens to the liver and fat metabolism when you eat extra fat for a short time. It may help researchers understand how diet affects liver function and metabolism in otherwise stable adults.
OxfordAges 18–65 - NCT06751862Recruiting
How sugars affect fat in the liver
This study looks at how different types of sugars affect fat buildup in the liver. It is for men who are either at a healthy weight or have obesity, and also for men with a specific amount of liver fat (mild to moderate fatty liver).
Prague, Czech RepublicAges 18–70 - NCT07441252RecruitingPhase 2
Study of maridebart cafraglutide for fatty liver with obesity
This trial tests a new medication (maridebart cafraglutide) to see if it can reduce fat in the liver and help with weight loss. It may be an option for adults with excess liver fat and obesity or overweight who haven't been able to lose weight with diet and exercise alone.
Chandler, ArizonaAges 18–99 - NCT07214870RecruitingPhase 1
A study of a new medicine for liver disease in adults with extra body weight and liver fat
This trial tests a potential new medicine (NNC4005-0001) for liver disease in adults who have extra body weight and excess fat in their liver. It aims to see if the medicine can help improve liver health.
Montreal, QuebecAges 18–69 - NCT04899102Recruiting
Intermittent fasting for fatty liver disease in adults
This study tests whether intermittent fasting can improve fatty liver disease (NAFLD) by reducing liver fat. It focuses on adults with confirmed fatty liver and extra liver fat seen on a special MRI scan.
Boston, MassachusettsAges 18 years+ - NCT05334836Recruiting
Scan for fat in the pancreas and link it to cyst features
This study uses scans to measure how common “fatty change” is in the pancreas. It then looks at whether fatty change is related to specific features of pancreatic cysts (and may also include healthy people).
Shatin, New TerritoriesAges 18 years+ - NCT06060392Recruiting
Semaglutide pill for liver fat in transplant patients with diabetes
This study tests if an oral semaglutide pill can reduce liver fat and improve body composition in people who have had a liver transplant and have diabetes. It may help manage weight and blood sugar after transplant.
Gurgaon, HaryanaAges 30 years+ - NCT07481734RecruitingPhase 2
Tesamorelin for reducing liver fat in fatty liver disease
This trial tests if tesamorelin, a daily injection, can reduce liver fat in adults with fatty liver disease. It may help people whose liver has fat but is not yet scarred into cirrhosis.
Shenzhen, GuangdongAges 18–75 - NCT05294471Recruiting
Automated MRI to measure liver fat and iron
This study uses an automated MRI scan to measure things in the liver, such as liver fat and iron levels. It may help researchers better understand liver changes and improve how these measurements are done.
Madison, WisconsinAges 7 years+ - NCT06888570Enrolling by invitation
Liver health study for children & young adults with Down syndrome
This study looks at how eating patterns and body composition relate to fatty liver in children and young adults with Trisomy 21 (Down syndrome) or other genetic intellectual disabilities. It may help understand who is at risk and how to prevent liver problems.
Madrid, MadridAges 5–22 - NCT06035874Recruiting
Bempedoic acid for fatty liver in type 2 diabetes
This trial tests if bempedoic acid, a cholesterol-lowering drug, can reduce liver fat in people with type 2 diabetes and nonalcoholic fatty liver disease. It may help those who have stable blood sugar and are not on certain other medications.
Gurgaon, HaryanaAges 20 years+ - NCT06512701Recruiting
Fat-soluble vitamins and fatty liver disease study
This study looks at how fat-soluble vitamins (like vitamins A, D, E, and K) are related to non-alcoholic fatty liver disease (NAFLD). It may help understand if vitamin levels affect your liver health.
Hangzhou, ZhejiangAges 18 years+ - NCT07321925Recruiting
Using sound waves to measure liver fat
This study tests a new method that uses sound waves to measure fat in your liver. It could help doctors check liver health without a biopsy.
Ann Arbor, MichiganAges 18 years+ - NCT07192159Recruiting
Ultrasound vs MRI for measuring liver fat in MASLD
This study compares ultrasound (DeepUSFF) and MRI (MRI-PDFF) for measuring liver fat in people with MASLD (a type of fatty liver disease not caused by alcohol). It aims to see if ultrasound can be used as a cheaper, more accessible alternative to MRI.
Boardman, OhioAges 18 years+ - NCT07097506RecruitingPhase 2
Ketone drink for liver fat and health
This study tests whether a daily ketone ester drink can reduce liver fat and improve metabolism in people with excess liver fat. You may join if you are 18–40, have overweight or obesity, and your liver has extra fat.
St Louis, MissouriAges 18–40 - NCT06704321Recruiting
Effects of TOTUM-448 on liver fat and heart health
This trial tests a supplement called TOTUM-448 to see if it can reduce liver fat and improve heart health in people with a fatty liver condition (MASLD). If you have excess liver fat and are overweight, this study could help find new ways to manage your condition.
Québec, QuebecAges 18–75 - NCT07083336Recruiting
Diet study for type 2 diabetes with fatty liver disease
This trial tests a specific medical nutrition therapy diet to see if it can reduce liver fat and improve blood sugar control in people with type 2 diabetes and nonalcoholic fatty liver disease. It may help you manage both conditions with a dietary approach.
Yichang, HubeiAges 18 years+ - NCT05439226Recruiting
Diet plan targeting liver fat for type 2 diabetes
This study tests whether a Chinese medical nutrition therapy diet can reduce liver fat and help manage type 2 diabetes in people who also have fatty liver. You may be asked to follow a specific eating plan and keep your diabetes care stable during the study.
Yichang, HubeiAges 18–75 - NCT06124456Recruiting
Vigorous vs. moderate exercise for liver fat reduction
This study compares high-intensity exercise to moderate-intensity exercise to see which is better at reducing fat in the liver for people with obesity and fatty liver disease.
Hong KongAges 18–69 - NCT06211556Recruiting
Reducing liver fat in type 2 diabetes
This study tests whether reducing liver fat can improve health in people with type 2 diabetes. It looks at the effects of a specific medication combined with exercise, tailored for those who are not very active.
Copenhagen, Capital RegionAges 30–70 - NCT06843148Recruiting
Does niacin help move fat from liver to fat tissue?
This study tests if niacin (a B vitamin) can help the body store fat safely in fat tissue instead of letting it build up in the liver. It may be an option for people with fatty liver linked to belly fat, without serious liver damage or other health issues.
Sherbrooke, QuebecAges 20–80
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Common questions
- Are there clinical trials for liver fat?
- Yes. Clin2 currently lists 35 recruiting liver fat studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver fat trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver fat trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.