Clinical trials
Lumbar Disc Disease clinical trials
Below are recruiting lumbar disc disease clinical trials, each written for real people, not researchers. We’re tracking 77 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05444751Enrolling by invitationPhase 3
Different pain medicine plans for back surgery
This Phase 3 study compares two combinations of anesthesia and pain medications during lumbar decompression surgery, to see which helps more. It may help patients by aiming for better pain control and recovery using one planned medication approach.
New York, New YorkAges 18–80 - NCT05029726RecruitingPhase 4
Numbing medicine during back surgery to reduce pain
This trial tests a regional anesthesia (numbing medicine given near nerves) during minimally invasive lumbar spine surgery. The goal is to see if it helps control pain around surgery and improves recovery comfort.
Chicago, IllinoisAges 18–80 - NCT04641039Recruiting
Study of scar differences after lumbar disc replacement
This study compares how postoperative scars look and behave after certain lumbar disc replacement surgery. It may help doctors choose approaches that reduce excessive scar-related problems after surgery.
Valencia, ValenciaAges 18–50 - NCT07862257Recruiting
Checking brain oxygen during spine surgery lying face-down
This study measures how lying face-down during lumbar disc surgery affects your breathing and the oxygen levels in your brain. The researchers want to see if this position is safe and how it changes blood flow and oxygen to your brain during the operation.
Istanbul, IstanbulAges 18–75 - NCT07834931Recruiting
Spine implant for low back pain from disc degeneration
This study tests an implant placed in the lower spine to treat back pain caused by disc degeneration. It aims to see if the implant helps reduce pain and improve function in people who have not improved with other treatments.
Madrid, MadridAges Any age - NCT07834736Recruiting
Titanium implant for lower back disc pain
This study tests a new titanium implant to help stabilize the lower spine in people with painful, worn-out discs. It aims to see if the implant works well and is safe in everyday practice.
Madrid, MadridAges Any age - NCT07335718Recruiting
Radiofrequency therapy for low back pain from disc herniation
This trial tests if a type of radiofrequency treatment (TECAR therapy) can reduce pain and improve function and quality of life for people with low back pain caused by a herniated disc. It involves an exercise program along with the treatment.
AnkaraAges 20–60 - NCT05287867Recruiting
Study for painful degenerative disc disease treatment
This trial is testing a treatment approach for people with long-lasting, painful worn-out discs in the lower back (and sometimes leg pain). It looks for people who tried common non-surgical options without enough relief and who may be headed toward a lumbar procedure.
Broomfield, ColoradoAges 25–65 - NCT07161232Recruiting
When to start rehab after UBE spine surgery
This study looks at whether starting rehabilitation exercises earlier or later after a specific type of minimally invasive back surgery (UBE) for a slipped disc improves your recovery. It's for people who have had leg pain for less than a year and are scheduled for this surgery.
Beijing, Beijing MunicipalityAges 19–65 - NCT07001969Enrolling by invitation
Percutaneous facet spine fixation for instability
This study tests a minimally invasive procedure to fix unstable vertebrae in the neck or lower back using a small incision. It may help people with spinal instability causing nerve symptoms or pressure on the spinal cord.
Cairo, ShoroukAges Any age - NCT04775537Recruiting
OssiMend bone graft for lumbar spine fusion surgery
This trial studies whether OssiMend bone graft helps heal a lumbar spine fusion for people whose disc disease has not improved with non-surgical care. It may be an option if you need back surgery due to specific spine wear-and-tear changes.
Encinitas, CaliforniaAges 18 years+ - NCT06024460Recruiting
Non-Drug vs Drug Therapy for Chronic Slipped Disc
This study compares non-medication treatments (like acupuncture and manual therapy) with standard pain medication for people with a slipped disc in the lower back that has lasted at least a month. It tests whether natural therapies can work just as well or better than drugs.
Seoul, Gangnam-GuAges 19–69 - NCT05997121Recruiting
Testing a new spinal implant for degenerative disc disease
This trial studies a new spinal implant system (Hexanium TLIF) for people with degenerative disc disease. It aims to see if the implant is safe and works well to help with back pain and stability.
BrugesAges 18 years+ - NCT07614555Recruiting
Breathing methods during back surgery recovery
This study compares two ways doctors control your breathing during lumbar disc herniation (slipped disc) surgery. Researchers want to see which method keeps your lungs healthier during the operation.
AnkaraAges 18–65 - NCT07250581Recruiting
Disc repair surgery with removal for herniated disc: a comparison
This trial compares two types of surgery for a herniated disc in the lower back: one that only removes the damaged disc piece (discectomy), and another that also repairs the disc outer wall. It aims to see if adding the repair leads to better long-term results.
QingdaoAges 12–65 - NCT07721220Recruiting
Nerve gliding moves for strength and endurance in athletes
This study tests whether a gentle nerve-stretching technique (neurodynamics) can improve leg strength and endurance in athletes. If you're 18–30, currently active in sports or intense training, and have no recent leg injury or surgery, you may be able to join.
High Point, North CarolinaAges 18–30 - NCT07830836Enrolling by invitation
Physiotherapy and osteopathy for recent neck, back, or jaw pain
This study tests whether physiotherapy and osteopathic treatment can help relieve recent (acute) pain in the neck, lower back, or jaw joint. It aims to understand if these hands-on therapies reduce pain and improve jaw function.
Gorzów Wielkopolski, Lubusz VoivodeshipAges 20–40 - NCT06709391Recruiting
Spinal fusion vs. no surgery for chronic low back pain
This trial tests whether a spinal fusion surgery is better than staying with non-surgical treatments for people with long-term, severe low back pain from worn-out discs in the lower spine. It aims to find out which approach offers better pain relief and quality of life.
GothenburgAges 25–65 - NCT07322523Recruiting
Smartwatch study before disc surgery
This study tests if a smartwatch can accurately measure your heart rate and anxiety levels the night before disc surgery. You'll wear the watch for 8 hours to see if it's a good alternative to hospital monitors.
KayseriAges 22 years+ - NCT06029764Recruiting
Extended fusion for spinal disc vacuum signs
This trial tests a surgery that fuses one extra spinal disc to treat a 'vacuum sign' (air pockets in the disc) that hasn't caused symptoms yet. It aims to prevent future problems in people with lumbar disc disease who need fusion surgery.
Beijing, Beijing MunicipalityAges 18–60 - NCT04540068Recruiting
Predicting whether a sciatica procedure will work
This study looks for ways to predict how well a specific sciatica procedure (TEI) will help. If you have one-sided nerve pain from the low back, the trial may help personalize treatment so you’re less likely to go through ineffective care.
HaarlemAges 18 years+ - NCT06352710Recruiting
Tracking recovery after brain or spine surgery
This study uses a smartphone app to track how you recover after brain or spine surgery. It helps doctors understand how side effects affect your daily life, so they can improve care.
Sankt Gallen, St.GallenAges 18 years+ - NCT06872918Recruiting
Study of a back manipulation for lumbar disc herniation
This study tests a specific type of back manipulation (Lever Positioning Manipulation) to understand how it affects the discs in the lower spine. It may help people with a herniated disc at L4-L5 find a non-surgical treatment option.
Hangzhou, ZhejiangAges 20–60 - NCT04467944Recruiting
Lumbar fusion outcomes with arthritis in nearby spine segments
This study looks at how well lumbar fusion surgery works long-term when the joint just above or below (adjacent segment) already shows wear-and-tear. It may help predict who benefits most and guide treatment planning.
Beijing, Beijing MunicipalityAges 18–80
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Common questions
- Are there clinical trials for lumbar disc disease?
- Yes. Clin2 currently lists 77 recruiting lumbar disc disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lumbar disc disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lumbar disc disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.