Clinical trials
Metastasis clinical trials
Below are recruiting metastasis clinical trials, each written for real people, not researchers. We’re tracking 338 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06531278RecruitingPhase 2
Adebelimab plus chemo for first-line pancreatic cancer with liver spread
This trial tests a combination of immunotherapy (adebelimab) and chemotherapy drugs (irinotecan liposome, oxaliplatin, fluorouracil, and calcium folinate) as a first treatment for pancreatic cancer that has spread to the liver. The goal is to see if this combination is safe and effective.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06185556RecruitingPhase 2/Phase 3
New treatments for liver tumors near blood vessels or bile ducts
This trial tests two procedures—irreversible electroporation and stereotactic body radiotherapy—for people whose colorectal cancer has spread to the liver (1–3 tumors near major blood vessels or bile ducts) and can't be surgically removed or treated with heat. The goal is to see if these approaches can safely destroy those hard-to-reach tumors.
Amsterdam, North HollandAges 18 years+ - NCT06501391RecruitingPhase 2
Brain radiation plus chemo-immunotherapy for untreated NSCLC with stable brain metastases
This trial tests whether combining brain radiation with chemotherapy and immunotherapy can help people with advanced lung cancer that has spread to the brain but has not yet been treated. It is for those whose tumors do not have certain gene mutations (EGFR, ALK, ROS1).
ShanghaiAges 18 years+ - NCT06585007RecruitingPhase 3
Radiation for limited cancer growth in castration-resistant prostate cancer
This trial tests whether giving focused radiation to limited areas of cancer growth (up to 3 spots) can help control the disease in men with castration-resistant prostate cancer. You may be eligible if your cancer is growing slowly and you are already on hormone therapy.
LeuvenAges 18 years+ - NCT07755397RecruitingPhase 1
Study of JBI-778 for lung, brain, and salivary gland tumors
This trial tests a new oral medication, JBI-778, in patients with certain types of lung cancer, brain tumors, or salivary gland cancer. The drug is designed to target specific genetic changes in these tumors, and the study aims to assess its safety and effectiveness.
Surat, GujaratAges 18 years+ - NCT06590259RecruitingPhase 2
Ablation plus drug therapy for colorectal cancer liver metastases
This trial tests a combination treatment that uses heat or cold (ablation) to destroy liver tumors along with medicines that boost your immune system to fight cancer. It is for people whose colorectal cancer has spread to the liver and who could not have surgery, or whose first treatment stopped working.
ShanghaiAges 18–75 - NCT07744529RecruitingPhase 1/Phase 2
Combination treatment for lung cancer spread to the lining of the brain
This trial tests a new combination of two drugs for people with a specific type of lung cancer that has spread to the lining of the brain and spinal cord. The treatment aims to target the cancer cells and may help improve symptoms and survival.
Hangzhou, ZhejiangAges 18 years+ - NCT07740239Recruiting
Study on frailty in seriously ill adults
This study looks at why some seriously ill adults become frail. It involves imaging and other tests to help doctors better understand and care for patients with serious conditions.
TampereAges Any age - NCT06619002Recruiting
Using video to make uterine cancer surgery safer
This study is collecting videos from a type of minimally invasive surgery called sentinel lymph node dissection for endometrial or cervical cancer. The goal is to use deep learning (a type of artificial intelligence) to help surgeons identify important structures and any spread of cancer during the procedure, making the surgery safer and more effective.
RomaAges 18–99 - NCT07698899RecruitingPhase 1
Study of a new treatment for childhood brain and CNS cancers
This trial tests a radioactive drug (177Lu-DTPA-Omburtamab) given directly into the fluid around the brain for children and teens with certain brain cancers or cancers that have spread to the central nervous system. It aims to see if this treatment is safe and effective for tumors that have come back or not responded to other therapies.
Basking Ridge, New JerseyAges 3–22 - NCT07691255Recruiting
Melanoma Brain Tumors Treated with CyberKnife
This trial tests CyberKnife, a precise radiation treatment, for melanoma that has spread to the brain. It may help you if you haven't had whole-brain radiation or brain surgery before.
Milan, ItalyAges 18 years+ - NCT06646341Recruiting
Can scan findings predict colorectal cancer spread?
This study looks at whether signs of blood vessel involvement (called EMVI) seen on scans can predict if colorectal cancer spreads to other organs. You might join if you already had surgery to remove the cancer from the colon or rectum and any distant tumors, and your before-surgery scans are available for review.
Basingstoke, HampshireAges 16–100 - NCT07660276Enrolling by invitation
AI predicts prostate cancer spread from biopsy
This study uses an artificial intelligence (AI) system to look at prostate biopsy samples and predict if the cancer has spread to the lymph nodes. It may help doctors decide on the best treatment without needing extra surgery or scans.
Changsha, HunanAges 18–90 - NCT05933876Recruiting
Radiation study for limited spread cancer
This trial looks at whether giving radiation treatment to tumors in people with a limited number of metastases can help control the cancer. It is for adults with certain cancer types that have spread to specific organs, and who can manage daily activities with little or no help.
Albacete, AlbaceteAges 18 years+ - NCT06126419Recruiting
High-dose insulin for liver function after surgery
This trial tests if high-dose insulin can help your liver work better and heal faster after a major liver surgery for colorectal cancer that has spread to the liver.
Montreal, QuebecAges 18 years+ - NCT07627282Recruiting
Understanding spine care evolution and patient outcomes
This study follows patients visiting a spine surgery department to better understand how care is provided and how patients do over time. It helps doctors improve treatment for spine problems like degeneration, deformity, injury, infection, or tumors.
BordeauxAges 18 years+ - NCT07623577RecruitingPhase 2
Sac-TMT and Bevacizumab for Triple-Negative Breast Cancer Brain Tumors
This trial tests a combination of two drugs (Sac-TMT and bevacizumab) to treat triple-negative breast cancer that has spread to the brain. Triple-negative means the cancer cells lack three common markers, making it harder to treat with standard therapies.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06538896RecruitingPhase 2
Tislelizumab and nab-paclitaxel for advanced triple-negative breast cancer with bone spread
This trial tests a combination of two drugs, tislelizumab (an immunotherapy) and nab-paclitaxel (a chemotherapy), as the first treatment for advanced triple-negative breast cancer that has spread to the bones. It aims to see if this combination can help shrink or control the cancer.
Hangzhou, ZhejiangAges 18–70 - NCT07602569Recruiting
New PET Scan for Finding Cancers More Accurately
This study tests a new type of PET scan (a special imaging test) called 18F-FGIn to help doctors better detect and evaluate cancers. It may be more accurate than the standard PET scan for certain tumors like brain, liver, stomach, and colon cancers.
GuangzhouAges 18–70 - NCT04798898Recruiting
RFA plus immune stimulation during liver surgery for colon cancer spread
This trial looks at whether using a heat-based treatment (RFA) to trigger the immune system before or during liver surgery can improve outcomes for people with colon cancer that has spread to the liver. It’s aimed at people who plan to have the liver tumors removed because they look treatable.
AarhusAges 18–99 - NCT07584824Recruiting
Cancer Care Laws and Modern Technology Survey
This survey asks cancer patients, their relatives, and healthcare workers in the UK about how well current cancer care laws work with today's technology. Your feedback helps shape future cancer care policies and practices.
TruroAges 18 years+ - NCT06418594RecruitingPhase 2
Drug combo for HER2-negative breast cancer brain metastasis
This trial tests a combination of two drugs (adebrelimab and apatinib) plus chemotherapy for women with HER2-negative breast cancer that has spread to the brain. It aims to see if this treatment can help shrink or control brain tumors.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07562581RecruitingPhase 2
Two Drugs for Advanced Lung Cancer With KRAS Mutation
This trial tests two drugs (luvometinib and anlotinib) together to treat advanced lung cancer that has a KRAS mutation and has grown despite previous treatment. The goal is to see if this combination helps patients live longer and slows cancer growth.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07552233Recruiting
NK Cell Therapy for Recurrent Brain Tumors
This trial tests a new type of immune cell therapy (NK cells) for patients with malignant brain tumors that have come back or worsened despite previous treatment. The goal is to see if these specially prepared immune cells can help fight the cancer.
Beijing, Beijing MunicipalityAges 18–70
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Common questions
- Are there clinical trials for metastasis?
- Yes. Clin2 currently lists 338 recruiting metastasis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metastasis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metastasis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.