Clinical trials
Metastasis clinical trials
Below are recruiting metastasis clinical trials, each written for real people, not researchers. We’re tracking 338 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07552233Recruiting
NK Cell Therapy for Recurrent Brain Tumors
This trial tests a new type of immune cell therapy (NK cells) for patients with malignant brain tumors that have come back or worsened despite previous treatment. The goal is to see if these specially prepared immune cells can help fight the cancer.
Beijing, Beijing MunicipalityAges 18–70 - NCT07517419Enrolling by invitationPhase 2
Pressurized chemotherapy for gastric cancer spread in abdomen
This trial tests a specialized chemotherapy delivery method called PIPAC—where chemotherapy is sprayed directly into the abdomen under pressure—for patients with gastric cancer that has spread to the abdominal lining. The goal is to deliver stronger doses of chemotherapy directly to where the cancer is, potentially helping patients who aren't candidates for major surgery.
Hong KongAges 18–80 - NCT06756334RecruitingEarly Phase 1
Comparing Two PET/CT Scans for Prostate Cancer
This study compares two types of PET/CT scans (using different radioactive tracers) to see which one is better at finding prostate cancer, detecting if it has come back, or spotting spread to other parts of the body. You will get both scans so doctors can compare them directly.
Hefei, AnhuiAges 18–90 - NCT07504471RecruitingPhase 2
Bicarbonate plus chemo and immunotherapy for pancreatic cancer liver spread
This trial tests adding sodium bicarbonate to a chemotherapy plus immunotherapy regimen for pancreatic cancer that has spread to the liver. The goal is to see if this combination helps shrink tumors and improves outcomes.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04724928RecruitingPhase 2
PET-CT scan to guide bladder cancer treatment decisions
This Phase 2 study checks whether an FDG PET-CT scan can help doctors better predict bladder cancer risk and adjust treatment. You may still get standard bladder cancer care, but the study uses the scan results to help decide how aggressive treatment should be.
GhentAges 18 years+ - NCT07488507Recruiting
Combined biopsy for lung cancer spread in the chest
This trial tests a new way to take tissue samples from suspicious spots in the chest (mediastinum) in people with lung cancer. It aims to see if combining two biopsy methods is safer and more accurate than one alone.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT07476651Recruiting
Study of a scout dose of resin microspheres for liver cancer
This trial is testing a low 'scout' dose of tiny radioactive beads (resin microspheres) given into the liver to treat liver cancer. The goal is to see if this approach is safe and helps patients with certain types of liver cancer that cannot be surgically removed.
SeoulAges 19 years+ - NCT07478289RecruitingPhase 2
Radiation boost for painful spinal metastases
This trial tests a higher dose of radiation (a boost) to painful spots in the spine where cancer has spread. The goal is to see if it can better relieve pain and improve function.
Toronto, OntarioAges 18 years+ - NCT07477457RecruitingPhase 2
Targeted drugs plus chemo for advanced osteosarcoma
This trial combines four targeted drugs (gefitinib, trametinib, disulfiram, sunitinib) with standard chemotherapy to treat osteosarcoma that has spread or come back. The goal is to see if this drug mix helps shrink tumors or keep them from growing.
Basking Ridge, New JerseyAges 6–49 - NCT06601075Recruiting
FDG and FAPI PET Scans for Advanced Colorectal Cancer
This trial uses two types of PET/CT scans (FDG and FAPI) to better see and track colorectal cancer that has spread to the belly lining (peritoneum). It aims to help doctors choose the best treatment by improving how they detect and monitor the cancer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06793332RecruitingPhase 2
Ivonescimab and Trodelvy for breast cancer with brain metastases
This trial tests two drugs (Ivonescimab and a Trop2 ADC) for people with triple-negative breast cancer that has spread to the brain. It aims to see if this combination can shrink brain tumors and help patients live longer.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07443020RecruitingPhase 1
Fast immune cells for fluid build-up from cancer
This trial tests a treatment using your own immune cells (T cells) to fight cancer that has spread to the lining of the lung and is causing fluid buildup. It may help if other standard treatments have stopped working.
Pittsburgh, PennsylvaniaAges 18–79 - NCT06810349Recruiting
Using AI to find cancer origin from lymph node biopsy
This study uses computer intelligence (deep learning) to analyze cells from a lymph node biopsy to find where in the body a cancer might have started. It looks at past patient data and images to train a program that could help doctors in the future.
Chengdu, SichuanAges Any age - NCT06718933RecruitingPhase 1/Phase 2
Study of a drug combination for breast cancer that spread to the brain
This trial tests whether a combination of three drugs (SHR-A1811, pyrotinib, and bevacizumab) can help people with advanced breast cancer that has spread to the brain. It aims to shrink brain tumors and stop them from growing.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07433660Recruiting
WellSpan Cancer Quality of Life Study
This study looks at quality of life in people recently diagnosed with cancer. It aims to understand how cancer and its treatment affect daily life and well-being.
Chambersburg, PennsylvaniaAges 18 years+ - NCT06023212RecruitingPhase 1/Phase 2
Tranexamic acid to prevent bleeding in spine surgery for lung cancer
This trial tests if a medicine called tranexamic acid can help reduce bleeding during surgery for lung cancer that has spread to the spine. It may be an option if you have a single tumor in your spine and are having separation surgery.
Hangzhou, ZhejiangAges 10–80 - NCT05257967Recruiting
Testing spinal fluid in EGFR-mutant lung cancer with brain covering spread
This trial looks at spinal fluid (also called CSF) in adults with EGFR-mutant lung cancer that has spread to the lining around the brain/spinal cord. The goal is to better understand the disease and what the spinal fluid tests may show to guide care.
Vancouver, British ColumbiaAges 18 years+ - NCT07409805RecruitingPhase 1
Vaccine trial for advanced colorectal cancer with liver spread
This trial tests a new vaccine (YMN-136) for people with colorectal cancer that has spread to the liver and hasn't responded to at least three prior treatments. The goal is to see if the vaccine can help control the cancer.
Chengdu, SichuanAges 18–75 - NCT07398599Recruiting
Double-dose targeted therapy plus chemo for lung cancer spread to brain lining
This trial tests a stronger dose of an EGFR-targeted drug combined with bevacizumab and chemotherapy into the spinal fluid for patients with non-small cell lung cancer that has spread to the lining of the brain and is no longer responding to standard treatment.
Nanchang, JiangxiAges 18–99 - NCT07399236Recruiting
AI prediction of liver spread in colorectal cancer
This study looks at whether an AI tool can predict if colorectal cancer will spread to the liver. The researchers will review past medical records of patients who had surgery to remove their cancer and had no signs of spread at that time.
Wuhan, HubeiAges 18–75 - NCT06225843RecruitingPhase 2
Testing a new drug combo before liver surgery for colorectal cancer
This trial is for people with colorectal cancer that has spread to the liver. It tests whether adding a new drug (sotevtamab) to standard chemotherapy (FOLFOX) before surgery can help shrink tumors and improve outcomes.
Montreal, QuebecAges 18 years+ - NCT07384234RecruitingPhase 2
Testing a new drug plus chemo for stomach cancer with belly spread
This trial tests a new immunotherapy drug (SHR-1701) combined with chemotherapy for people with stomach or gastroesophageal junction cancer that has spread to the lining of the abdomen (peritoneal metastasis) but not to other organs like the liver or lungs. The goal is to see if this combination can help shrink or control the cancer before any surgery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06840418Recruiting
New imaging to find cancer spread in cervical cancer surgery
This study tests a new imaging technique (NIRFI with ICG dye) to help surgeons see if cervical cancer has spread to lymph nodes during your hysterectomy surgery. It may help guide more precise removal of affected nodes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07372261Enrolling by invitation
Predicting breast cancer spread risk
This study tests a method to predict if early-stage breast cancer might spread to other parts of the body. It uses leftover tumor tissue to help doctors plan your treatment.
San Giovanni Rotondo, FGAges 18 years+
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Common questions
- Are there clinical trials for metastasis?
- Yes. Clin2 currently lists 338 recruiting metastasis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metastasis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metastasis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.