Clinical trials
Muscle clinical trials
Below are recruiting muscle clinical trials, each written for real people, not researchers. We’re tracking 1,160 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03800017Recruiting
Muscle strength and exercise function in lung scarring
This study looks at how well skeletal (muscle) function supports exercise in people with interstitial lung diseases (including idiopathic pulmonary fibrosis). It may help better understand fitness and breathing limits, which can guide rehabilitation choices and future care.
Vancouver, British ColumbiaAges 40–80 - NCT03844256RecruitingPhase 1/Phase 2
Bladder-sparing chemo-radiation plus immunotherapy for bladder cancer
This study tests whether adding immunotherapy drugs (nivolumab alone or nivolumab plus ipilimumab) to standard chemo-radiation can control muscle-invasive bladder cancer while helping people keep their bladder. It aims to find a safer, effective curative treatment for people who want to avoid bladder removal (cystectomy).
Amsterdam, North HollandAges 18 years+ - NCT03940911Recruiting
Testing fatigue and muscle effects after starting targeted therapy
This study looks at how starting “targeted” treatment affects fatigue and skeletal muscle function in people with severe axial spondyloarthritis. It may help doctors understand what to expect early after treatment starts and how well it impacts day-to-day energy and muscle performance.
Strasbourg, Bas-RhinAges 18 years+ - NCT07701174Recruiting
Weighted exercise vs muscle stimulation for knee arthritis
This study compares two treatments for knee osteoarthritis: weighted dangling exercises and neuromuscular electrical stimulation of the knee muscle. It aims to see which one reduces pain and improves function better.
Lahore, Punjab ProvinceAges 40–60 - NCT04106115RecruitingPhase 1/Phase 2
Durvalumab vaccine trial for high-risk bladder cancer after BCG
This early-phase trial tests durvalumab given with an experimental bladder cancer vaccine to help stop or slow high-risk bladder cancer that did not respond to or cannot be treated with BCG. It also evaluates safety and how well the treatment works in this setting.
CambridgeAges 18 years+ - NCT04142047Recruiting
Study muscle energy and fatigue in older adults
This study measures how older adults’ muscles use energy and how easily they tire during activity. It includes both people with HIV (with stable treatment and an undetectable viral load) and people without HIV to better understand differences in fatigue.
Baltimore, MarylandAges 60–90 - NCT04234880Recruiting
MRI mapping of creatine in muscle and brain
This study uses a special MRI scan to measure chemicals related to energy (creatine and phosphocreatine) in the muscle and brain. It may help researchers build a detailed “map” of these substances, which could support future research on energy and movement-related conditions.
Baltimore, MarylandAges 18–80 - NCT04273828Recruiting
Study of muscle changes in chronic low back pain surgery
This study looks at how muscle degeneration relates to nerve-related symptoms in people with chronic low back pain. You may be eligible if you’ve tried non-surgical care but still need surgery to relieve nerve pressure.
São Paulo, São PauloAges 18 years+ - NCT04320264Recruiting
Study tests muscle fuel patterns in adults with BMI 25–30
This study looks at how your muscles use fuel during exercise by measuring blood lactate. It may help researchers understand “metabolic inflexibility” and why some people rely more on fast, short-lasting energy during activity.
Greenville, North CarolinaAges 18–50 - NCT04439370Recruiting
Blood pressure control study in women with early menopause
This study looks at how the body automatically regulates blood pressure in women who went through menopause earlier than expected. It may help researchers understand whether early menopause affects blood pressure control and related health risks.
Minneapolis, MinnesotaAges 35–70 - NCT04449198RecruitingEarly Phase 1
Study for mitochondrial and blood-vessel issues in type 1 diabetes
This early study looks at how a new approach may affect energy-making (mitochondria) and blood-vessel signaling in people with insulin-dependent type 1 diabetes. It may help researchers understand whether these pathways can be improved in type 1 diabetes.
Augusta, GeorgiaAges 18 years+ - NCT04460872RecruitingPhase 2
Testosterone plus walking training to support bones and muscles
This Phase 2 study tests whether testosterone therapy combined with walking training can improve bone and muscle health after a spinal cord injury. It aims to help men with low testosterone and walking problems by improving strength, body composition, and related health markers.
Gainesville, FloridaAges 18 years+ - NCT04492345Recruiting
Back muscle training for posture problems in Parkinson’s
This trial tests a special way to strengthen the back muscles to improve posture problems in people with Parkinson’s (or similar conditions). It may help reduce postural deformities and improve movement comfort while your Parkinson’s treatment stays steady.
Le LamentinAges 18–85 - NCT04547816RecruitingPhase 3
Non-surgical treatment for constipation-related prolapse in women
This study tests whether a non-surgical (“conservative”) approach can improve constipation-related bowel problems in women who have a mild-to-moderate rectal bulge from pelvic organ prolapse. It may help by addressing how the rectum and pelvic floor work during bowel movements.
MoscowAges 18–70 - NCT04575844RecruitingPhase 4
Exercise and GLP-1 to improve insulin and muscle blood flow
This study looks at whether doing exercise and a GLP-1 medicine (liraglutide or similar) can improve how your body uses insulin and how blood flows to your muscles. It is aimed at adults with metabolic syndrome who do not already have diabetes.
Charlottesville, VirginiaAges 21–60 - NCT04620343Recruiting
Study of breathing treatment for EILO during exercise
This trial tests a treatment approach for exercise-related breathing difficulty called EILO. It aims to help people whose breathing problems show up during peak exercise and who want ongoing follow-up.
Bergen, VestlandAges 12 years+ - NCT04641702RecruitingPhase 4
Testing new esophagus study tools for achalasia patients
This study tests detailed ways to measure esophagus movement and symptoms in people with achalasia or other esophagus motility disorders. It may help doctors better diagnose these conditions and improve how treatment planning and outcomes are tracked.
Atlanta, GeorgiaAges 18 years+ - NCT04701853Recruiting
Exercise training after permanent stoma surgery
This trial looks at a specific exercise program after planned surgery to create a permanent stoma (an opening for stool). The goal is to see whether the training helps people recover and function better after surgery.
GothenburgAges Any age - NCT04730622Recruiting
Studying muscle and bone changes after a hip fracture
This study looks at how bone health and muscle strength (“osteosarcopenia” — loss of both bone and muscle) change after a hip fracture in older adults. It may help doctors understand who is at higher risk and how to better support recovery after hip surgery.
BolognaAges 65 years+ - NCT04754672Recruiting
Exercise training to improve outcomes in advanced colon cancer
This trial studies whether supervised exercise—either aerobic fitness training or muscle-strength training—can improve outcomes for people with metastatic colorectal cancer. It compares which approach is most helpful and checks whether it’s safe during first-line chemotherapy.
's-HertogenboschAges 18 years+ - NCT04783155Recruiting
Breathing training after lung transplant at Mayo Clinic
This trial studies whether inspiratory muscle training (exercises to strengthen the breathing muscles) improves recovery and other health outcomes after a single- or double-lung transplant. It may help see if adding breathing exercises makes day-to-day function better and supports clinical recovery.
Jacksonville, FloridaAges 18 years+ - NCT04832100Recruiting
Study of a fat marker in fibromyalgia
This study looks at whether a specific fat-related marker (called LPC16:0) is linked to fibromyalgia. Your participation could help researchers understand what role this marker may play in the condition.
Kaohsiung CityAges 18–70 - NCT04849806Recruiting
Testing whether heart nerve signals predict COPD symptoms
This study looks at “sympathetic nerve activity” (signals from the nervous system that affect the heart) in adults with chronic obstructive pulmonary disease (COPD). The goal is to see whether these measurements can help predict what happens to people with COPD.
AachenAges 18 years+ - NCT04882904Recruiting
Tracking movement in people with ALS and healthy volunteers
This study continuously measures activity and movement in people with ALS and in control participants. It aims to better understand how muscle disease changes day-to-day function, which may help improve future monitoring or care.
Liège, LiègeAges 18 years+
Hear when a new Muscle trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for muscle?
- Yes. Clin2 currently lists 1,160 recruiting muscle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.