Clinical trials
Muscle clinical trials
Below are recruiting muscle clinical trials, each written for real people, not researchers. We’re tracking 1,160 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04896047Recruiting
Test whether FGF19 helps non-diabetic kidney disease
This study looks at FGF19 to see if it can improve chronic kidney disease in people who do not have diabetes. Participants may receive FGF19 (and may need extra testing such as muscle biopsies).
Pierre-BéniteAges 18–70 - NCT04899635Recruiting
Study tests heart muscle function during open-heart surgery
This study looks at how strong the heart muscle squeezes (contractility) using heart tissue from people having planned open-heart surgery. It may help researchers better understand “myocardial fatigue” to improve future heart care.
CoventryAges 18–85 - NCT04900558Recruiting
Study outcomes after robotic bladder removal surgery
This trial follows adults who are planning to have a robotic radical cystectomy (surgery to remove the bladder and surrounding tissue) to learn what outcomes to expect. If you choose to join and meet the basics, it may help your team compare results and improve care for future patients.
Florence, TuscanyAges 18 years+ - NCT04911491Recruiting
Breathing muscle training for people with kidney disease
This study tests whether training your breathing muscles can improve health in people with chronic kidney disease (stage 3–4). It may help how your body handles daily activity and circulation-related measurements, compared with usual care.
Aurora, ColoradoAges 50 years+ - NCT07511959Enrolling by invitation
Blood-derived treatment for chronic jaw pain
This trial tests whether a treatment made from your own blood (platelet-rich plasma exosomes) can help relieve long-term jaw joint pain and improve function. If you qualify, you would receive injections directly into your jaw area.
WroclawAges 18 years+ - NCT04936074Recruiting
Fusion vs no fusion after neck cord decompression
This trial compares two surgery approaches for people with a gradually worsening spinal cord problem in the neck: doing fusion (joining bones together) versus not doing fusion after decompression (making more space for the spinal cord). It aims to see which approach works better and is safer for symptoms and recovery.
UppsalaAges 18 years+ - NCT04949451Recruiting
Testing time-restricted eating for muscle and metabolism
This study looks at whether eating only during certain hours can improve muscle and metabolism in adults with higher body weight. You may be asked to follow a specific eating schedule and avoid things that could affect the results.
Fayetteville, ArkansasAges 25–50 - NCT04987814Recruiting
Testing a skin-sensor scan to detect muscle loss
This study uses a high-detail sensor placed on the skin to look for signs of sarcopenia, or age-related muscle loss. The goal is to see whether the scan can help diagnose sarcopenia more accurately.
Ivry-sur-SeineAges 75 years+ - NCT05007340Recruiting
ILD and autoimmune conditions registry and sample storage
This study collects health information and may store blood or other samples to learn more about interstitial lung disease (ILD) and autoimmune-related conditions. Joining could help researchers understand different causes of ILD and improve future care.
Montreal, QuebecAges 18 years+ - NCT05008705Recruiting
Protein and muscle stimulation for hospitalized seniors
This trial tests whether increasing protein intake plus using a gentle electrical muscle stimulation device can help maintain or build muscle mass in older adults while they are hospitalized. It may help prevent muscle loss that can happen after short hospital stays.
São PauloAges 65 years+ - NCT05013255RecruitingPhase 2
Pioglitazone to treat fatigue in hormone-positive breast cancer
This Phase 2 study tests whether pioglitazone can reduce fatigue in people with certain types of breast cancer. You may be eligible if your cancer is estrogen- and progesterone-positive (ER+/PR+) and you plan surgery soon.
Morgantown, West VirginiaAges 18 years+ - NCT05023005Recruiting
Strain-Counterstrain therapy for piriformis muscle pain
This trial tests a hands-on physical therapy technique called “strain-counterstrain” to reduce pain from the piriformis muscle. It may help people whose pain is coming from that specific muscle rather than the low back.
Loma Linda, CaliforniaAges 18–65 - NCT05037279RecruitingPhase 3
Testing BCG treatment for bladder cancer after full tumor removal
This trial studies a BCG-based bladder instillation in people with newly diagnosed, intermediate- or high-risk non-muscle invasive bladder cancer who have had their tumor fully removed. The goal is to see whether this treatment is safer and works better to lower the chance of the cancer coming back.
Vancouver, British ColumbiaAges 18 years+ - NCT05041387Recruiting
Collecting standard care data for nerve and muscle tests
This study collects information from people who may have a nerve or muscle problem or a nerve-degenerating illness, based on the usual care they already receive. It may help researchers understand symptoms and test results in real-world patients.
Bethesda, MarylandAges 18–110 - NCT05072600RecruitingPhase 2
Pembrolizumab after complete bladder cancer treatment response
This trial studies pembrolizumab (an immunotherapy) in people with muscle-invasive bladder cancer who had a combined “trimodality” treatment and then achieved a complete response. The goal is to help control the cancer after the initial treatment is finished.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05094362Recruiting
Training to reduce stiff leg reflexes after spinal cord injury
This study tests a special training approach designed to calm overactive leg reflexes (spasticity) after spinal cord injury. If you qualify, you may do structured walking/reflex training to see whether your leg reflexes and movement improve.
Charleston, South CarolinaAges 18 years+ - NCT05094297Recruiting
Study of muscle contraction training for veteran tiredness and pain
This study tests whether a guided exercise approach using focused muscle contractions can improve pain, fatigue, or low energy in U.S. Veterans. If you’re having trouble doing everyday activities, this program may help you feel better and function more easily.
Chicago, IllinoisAges 18 years+ - NCT05117255Recruiting
Online therapy study for anxiety in residential alcohol treatment
This study tests an internet-based, interactive version of cognitive behavioral therapy (CBT) for anxiety symptoms. It’s designed for people getting mainly alcohol-focused treatment in a residential program, to see if the online approach works and is feasible for you.
Minneapolis, MinnesotaAges 18–65 - NCT05147441Recruiting
Freezing the obturator nerve for tight hip muscles
This trial looks at cryoneurotomy, a procedure that “freezes” a nerve, to reduce spasticity (tight, stiff muscles) in the hip adductors. It may help some people with spasticity who are already receiving this standard nerve-freezing treatment as part of their care.
Victoria, British ColumbiaAges 12 years+ - NCT05166499Recruiting
Amino acids to help rebuild muscle in liver cirrhosis
This trial tests whether a special amino-acid supplement can help reverse muscle loss in people with cirrhosis (scarring of the liver). It may help maintain or improve muscle strength and overall function, but eligibility depends on your liver status and overall health.
Cleveland, OhioAges 21–65 - NCT05194137Recruiting
Training pelvic floor muscle with biofeedback or exam guidance
This study compares two ways to help women learn how to tighten the pelvic floor muscles. It may help women with pelvic floor problems and urinary leaking by improving muscle control using either biofeedback or clinician guidance.
Ribeirão Preto, São PauloAges 18 years+ - NCT05197764Recruiting
Track muscle growth in young children with spastic cerebral palsy
This study looks at how the muscles in the body grow in infants and young children with spastic cerebral palsy (a type of movement difference). It may help doctors better understand normal growth patterns and how care choices affect muscle development.
Leuven, Vlaams-BrabantAges 6 months–9 years - NCT05204108Recruiting
Ultrasound test to check bladder cancer muscle spread
This trial studies a special ultrasound scan with contrast dye to see whether bladder cancer has grown into the muscle layer. It may help doctors plan the best treatment before surgery.
Guangzhou, GuangdongAges 18–75 - NCT05211661Recruiting
Study breathing muscle changes in people on a ventilator
This study looks at how the diaphragm (a key breathing muscle) changes during and after being on a breathing machine in the ICU. It may help researchers understand why breathing can get weaker after ventilation and how to measure it safely (including with MRI).
AachenAges 18–75
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Common questions
- Are there clinical trials for muscle?
- Yes. Clin2 currently lists 1,160 recruiting muscle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.