Clinical trials
Obesity Type 2 Diabetes Mellitus clinical trials
Below are recruiting obesity type 2 diabetes mellitus clinical trials, each written for real people, not researchers. We’re tracking 165 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03455868Recruiting
Bone health check after bariatric surgery in people with diabetes
This study looks at how bariatric (weight-loss) surgery affects bone health in adults with type 2 diabetes. It may help doctors understand who needs extra bone protection after surgery.
Montreal, QuebecAges 18–60 - NCT06959901Recruiting
Health tracking app study for Hispanic teens
This trial tests a mobile app that helps teens keep track of their health habits, like physical activity and eating. It is designed for Hispanic or Latino teens ages 12-18 who have a BMI in a certain range and own an iPhone.
Houston, TexasAges 12–18 - NCT06957093Recruiting
AI‐assisted diabetes care vs standard management
This study tests whether an AI‐powered digital health platform can help people with type 2 diabetes better manage their blood sugar. If you use a smartphone and have had diabetes for at least a year, this may be a convenient way to receive extra support.
Changchun, JilinAges 18–75 - NCT06937203RecruitingPhase 1/Phase 2
A new obesity drug study for people with or without type 2 diabetes
This early-stage study tests an investigational drug called ARO-ALK7 to see if it helps adults with obesity lose weight. It includes people who have type 2 diabetes as well as those who do not, and requires that you have tried to lose weight with lifestyle changes in the past.
Morayfield, QLCAges 18–65 - NCT06923644Recruiting
Personalized nutrition plan to prevent metabolic disease
This study tests whether a personalized nutrition plan based on your unique metabolism can help prevent chronic metabolic diseases like type 2 diabetes. You will follow a tailored diet and have your health monitored over time.
MaastrichtAges 40–75 - NCT06907862Recruiting
SWITCH trial: swapping processed soy foods in a heart-healthy diet
This study tests whether swapping highly processed soy foods for less processed soy foods, as part of a heart-healthy diet, can improve blood pressure, blood sugar, and weight in adults with obesity and high blood pressure. It may be a good option if you have type 2 diabetes and are already on stable medications.
Toronto, OntarioAges 18 years+ - NCT06886126RecruitingPhase 2
Testing HDM1005 injection for weight loss in adults with obesity
This study tests an experimental injection called HDM1005 for adults with obesity who do not have diabetes. The goal is to see if it helps with weight loss when combined with diet and exercise.
NanjingAges 18–65 - NCT06845345Enrolling by invitationPhase 4
Can a special diet or pills help liver health?
This study compares two treatments for liver scarring in people with overweight or related health issues. One group follows a special diet with restricted eating times, while the other takes a combination of two medications (naltrexone and bupropion). It aims to see which approach better improves liver fibrosis.
RotterdamAges 18–75 - NCT06752772Recruiting
Wearable health coaching for blood pressure and weight
This study tests a digital health coaching program that uses a smartwatch and smartphone to help people manage conditions like high blood pressure, pre-diabetes, or weight. It aims to see if wearable technology can improve your health with personalized coaching.
SingaporeAges 21–75 - NCT06730113Recruiting
Young adults with type 2 diabetes and heart health study
This study looks at how type 2 diabetes starting in youth affects the heart over time. It also includes teens and young adults who are overweight or lean, and their biological parents, to compare heart health across these groups.
Washington D.C., District of ColumbiaAges 12–25 - NCT06169033Recruiting
Can belly fat scans predict weight-loss surgery success?
This study looks at how fat around your belly and inside your abdomen, seen on a CT scan, can predict how well bariatric (weight-loss) surgery will work for people with type 2 diabetes.
BeijingAges 16–70 - NCT06700538RecruitingPhase 1/Phase 2
Study of an experimental drug for obesity with or without type 2 diabetes
This study tests an experimental medication called ARO-INHBE in adults with obesity, including those who also have type 2 diabetes. The goal is to see if it helps with weight loss and is safe.
CamberwellAges 18–65 - NCT06695221Recruiting
Kefir trial for better health in Edmonton adults
This study tests if drinking kefir, a fermented dairy drink, can improve health in adults who are overweight or have high blood sugar or type 2 diabetes. It looks at how kefir might help with weight, blood sugar, and overall wellness.
Edmonton, AlbertaAges 24–70 - NCT06682481Recruiting
Pancreas-Liver Communication in Teens with Obesity
This study looks at how the pancreas and liver talk to each other in teens with obesity. It may help understand why some teens develop diabetes or fatty liver.
Geneva, Canton of GenevaAges 12–16 - NCT05544266Recruiting
Study rare diabetes patterns to better guide diagnosis
This study looks at people who may have a “non-typical” form of diabetes, including rare genetic causes or unusual symptoms. It may help your care team understand what type of diabetes you have and whether specific genetic testing could explain it.
Aurora, ColoradoAges Any age - NCT06600555Recruiting
Metabolic surgery for diabetes control
This trial tests a type of weight-loss surgery (called metabolic surgery) to see if it helps people with type 2 diabetes achieve better blood sugar control. It's for people who have struggled to manage their diabetes with standard treatments and have a BMI between 30 and 35.
VilleurbanneAges 18–65 - NCT06571474Recruiting
Fat Cell Function in Obesity and Metabolism Study
This study looks at how a type of immune cell (macrophage) in fat tissue processes lipids, and how that affects metabolism in people with different body weights. It may help us understand why some people with obesity develop diabetes and fatty liver while others do not.
Columbia, MissouriAges 18–70 - NCT06562907RecruitingPhase 1
Study of an experimental drug for weight and diabetes
This study tests an investigational drug called GS-4571 in healthy people, people with obesity, and people with type 2 diabetes. It aims to see how the drug affects the body and whether it might help with weight and blood sugar control.
Miami, FloridaAges 18–65 - NCT06525259Recruiting
Study on risk factors for type 2 diabetes in youth
This study looks for children and teens who are at high risk of developing type 2 diabetes to understand what factors lead to it. If your child is overweight, has slightly high blood sugar, and is in early to mid-puberty, they may be able to join.
Birmingham, AlabamaAges 8–15 - NCT06497595Recruiting
Lifestyle program to prevent muscle loss in older adults with diabetes on semaglutide
This trial tests whether a lifestyle program (diet and exercise) can help prevent muscle loss in people 65 and older with type 2 diabetes and obesity who are taking semaglutide. It may help you keep your strength and independence while losing weight.
Jerusalem, IsraelAges 65 years+ - NCT04187443RecruitingPhase 1
Drug MS-553 for diabetic eye swelling with reduced vision
This Phase 1 trial tests MS-553 to see how it works and how safely it can be given to people with diabetic retinopathy causing central macular swelling (macular edema). You may be considered if your vision and eye scan results match, and if you can follow frequent study visits.
Changsha, HunanAges 18 years+ - NCT06138821Recruiting
Endoscopic sleeve gastroplasty for obesity and MASH
This study tests if a procedure called endoscopic sleeve gastroplasty helps people with obesity and a liver condition called MASH lose weight and improve their liver health. It might be an option if you have both obesity and MASH and haven't had weight-loss surgery before.
Boston, MassachusettsAges 18 years+ - NCT06118931Recruiting
Time-Restricted Eating for Blood Sugar Control
This study tests whether eating only during a specific daily window helps control blood sugar in people with or at risk for type 2 diabetes. You'll follow a set eating schedule and use a phone app to track your meals.
Toronto, OntarioAges 40 years+ - NCT06043245Enrolling by invitation
Diabetes remission and weight loss surgery
This trial tests whether a specific type of weight loss surgery can help people with type 2 diabetes stop needing diabetes medication. It is for people with a very high body mass index (BMI over 45) who are currently on diabetes pills or insulin.
L'Hospitalet de Llobregat, BarcelonaAges 18–60
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Common questions
- Are there clinical trials for obesity type 2 diabetes mellitus?
- Yes. Clin2 currently lists 165 recruiting obesity type 2 diabetes mellitus studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity type 2 diabetes mellitus trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity type 2 diabetes mellitus trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.